Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Amritendu Koley"'
Autor:
Manjula Karpurapu, Kavita Kumari Kakarala, Sangwoon Chung, Yunjuan Nie, Amritendu Koley, Patrick Dougherty, John W Christman
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301904 (2024)
Our previous research demonstrated that PU.1 regulates expression of the genes involved in inflammation in macrophages. Selective knockdown of PU.1 in macrophages ameliorated LPS-induced acute lung injury (ALI) in bone marrow chimera mice. Inhibitors
Externí odkaz:
https://doaj.org/article/80cab4e703204059aed37f81a8620f5c
Publikováno v:
PNAS Nexus. 2
Ehrlichia chaffeensis is an obligatory intracellular bacterium that infects monocytes and macrophages, and causes human monocytic ehrlichiosis, an emerging life-threatening infectious disease. Ehrlichia translocated factor-1 (Etf-1), a type IV secret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec7355a4966aab12f6b3dd01b54dad84
https://doi.org/10.1093/pnasnexus/pgad017
https://doi.org/10.1093/pnasnexus/pgad017
Autor:
Amanda B. Hummon, Dehua Pei, Amritendu Koley, Jessica K Lukowski, Estelle Cormet-Boyaka, Jack Wellmerling, Patrick G Dougherty
Publikováno v:
J Med Chem
Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, encoding for a chloride ion channel. Membrane expression of CFTR is negatively regulated by CFTR-associated ligand (CAL). We previousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c9736ca5455a241d397e6d370d5c9b
https://doi.org/10.1021/acs.jmedchem.0c01528
https://doi.org/10.1021/acs.jmedchem.0c01528
Autor:
Manjula Karpurapu, Jessica K Lukowski, Amritendu Koley, John W. Christman, Sangwoon Chung, Patrick G Dougherty, Dehua Pei, Ziqing Qian, Amanda B. Hummon, Hao W Li, Teja Srinivas Nirujogi, Luiza Rusu
Publikováno v:
J Med Chem
Acute respiratory distress syndrome (ARDS) is an inflammatory lung disease with a high morbidity and mortality rate, for which no pharmacologic treatment is currently available. Our previous studies discovered that a pivotal step in the disease proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771fd508385612589b19f0ff97624616
https://doi.org/10.1021/acs.jmedchem.0c01236
https://doi.org/10.1021/acs.jmedchem.0c01236
Autor:
Ashweta Sahni, George Appiah Kubi, Ziqing Qian, Jian-Guo Ren, Amritendu Koley, Patrick G Dougherty, Jin Wen, Ruchira Basu, Xiaoyan Pan, Dehua Pei, Heba Salim
Publikováno v:
J Med Chem
Stapled peptides recapitulate the binding affinity and specificity of α-helices in proteins, resist proteolytic degradation, and may provide a novel modality against challenging drug targets such as protein-protein interactions. However, most of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8209ea802cefe2b26a8c964426c9034b
https://doi.org/10.1021/acs.jmedchem.9b00456
https://doi.org/10.1021/acs.jmedchem.9b00456