Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Amrisha Verma"'
Autor:
Amrisha Verma, Kang Xu, Tao Du, Ping Zhu, Zhibing Liang, Shengquan Liao, Juantao Zhang, Mohan K. Raizada, Maria B. Grant, Qiuhong Li
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 400- (2020)
Externí odkaz:
https://doaj.org/article/f1ce63a8b936467eb4dc244437b3e137
Autor:
Tuhina Prasad, Ping Zhu, Amrisha Verma, Paramita Chakrabarty, Awilda M. Rosario, Todd E. Golde, Qiuhong Li
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Age-related macular degeneration (AMD) is a progressive retinal neurodegenerative disorder characterized by extracellular deposits known as drusen. A major constituent of drusen deposits are Alzheimer disease-associated amyloid β (Aβ) pept
Externí odkaz:
https://doaj.org/article/0589970a57f643f6bdb56b0f1698983f
Autor:
Wendy W Batenburg, Amrisha Verma, Yunyang Wang, Ping Zhu, Mieke van den Heuvel, Richard van Veghel, A H Jan Danser, Qiuhong Li
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100954 (2014)
Dysfunction of renin-angiotensin system (RAS) contributes to the pathogenesis of diabetic retinopathy (DR). Prorenin, the precursor of renin is highly elevated in ocular fluid of diabetic patients with proliferative retinopathy. Prorenin may exert lo
Externí odkaz:
https://doaj.org/article/220ef079f3f54dc782a3ab68afdc36e3
Autor:
Liliana C. Baptista, Emily L. Zumbro, Zachary A. Graham, Abbi R. Hernandez, Taylor Buchanan, Yi Sun, YouFeng Yang, Anisha Banerjee, Amrisha Verma, Qiuhong Li, Christy S. Carter, Thomas W. Buford
Publikováno v:
Journal of Applied Physiology. 134:1135-1153
This manuscript uses a multiomics approach (i.e., microbiome, metabolomics, and transcriptomics) to explore the underlying mechanisms driven by a genetically modified probiotic (GMP) designed to express angiotensin (1–7) combined with moderate exer
Autor:
C. Aaron Smith, Haddon Smith, Lisa Roberts, Lori Coward, Gregory Gorman, Amrisha Verma, Qiuhong Li, Thomas W. Buford, Christy S. Carter, Patricia Jumbo-Lucioni
Publikováno v:
J Alzheimers Dis
Background: While extensive research on the brain has failed to identify effective therapies, using probiotics to target the gut microbiome has shown therapeutic potential in Alzheimer’s disease (AD). Genetically modified probiotics (GMP) are a pro
Autor:
Qiuhong Li, Thomas W. Buford, Anthony Knighton, Gonzalo E. Torres, Drake Morgan, Yi Sun, Christy S. Carter, Amrisha Verma, Lisa M. Roberts, Anisha Banerjee, Sujitha Peramsetty
Publikováno v:
GeroScience
To (1) investigate the efficacy of multiple doses of an orally delivered probiotic bacteria Lactobacillus paracasei (LP) modified to express angiotensin (1–7) (LP-A) in altering physiologic parameters relevant to the gut-brain axis in older rats an
Autor:
Abbi Hernandez, Yi Sun, Anisha Banerjee, YouFeng Yang, Amrisha Verma, Qiuhong Li, Liliana Baptista, Thomas W Buford, Christy S Carter
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences.
Age-related declines in physical and cognitive function can have tremendous, negative impacts on health span and quality of life. Therefore, we investigated the potential of utilizing a probiotic treatment to target the renin–angiotensin system (RA
Autor:
Thomas W. Buford, Christy S. Carter, Elaine Sumners, Amrisha Verma, Drake Morgan, Gilberto O Lobaton, Victor Aquino, Mohan K. Raizada, Qiuhong Li
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
In recent years a number of beneficial health effects have been ascribed to the renin-angiotensin system (RAS) that extend beyond lowering blood pressure, primarily mediated via the angiotensin-converting enzyme-2 (ACE2)/angiotensin (1–7) or Ang(1
Autor:
Amrisha Verma, Ping Zhu, Zhibing Liang, Shengquan Liao, Kang Xu, Tao Du, Qiuhong Li, Mohan K. Raizada
Publikováno v:
Translational Vision Science & Technology
Purpose A multitude of animal studies substantiates the beneficial effects of Ang-(1-7), a peptide hormone in the protective axis of the renin angiotensin system, in diabetes and its associated complications including diabetic retinopathy (DR). Howev
Autor:
Jing Li, Iñaki Robles-Vera, Elaine M. Richards, Victor Aquino, Andrew Bryant, Ravindra K. Sharma, Qiuhong Li, Eric G. Krause, Amrisha Verma, Tao Yang, Annette D. de Kloet, Gilberto O Lobaton, Aline C. Oliveira, Mohan K. Raizada, Marianthi M. Karas
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 76(1)
Therapeutic advances for pulmonary hypertension (PH) have been incremental because of the focus on the pulmonary vasculature in PH pathology. Here, we evaluate the concept that PH is, rather, a systemic disorder involving interplay among multiorgan s