Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Amram Samuni"'
Publikováno v:
Antioxidants, Vol 11, Iss 1, p 40 (2021)
There is a considerable need for methods that allow quantitative determination in vitro and in vivo of transient oxidative species such as peroxynitrite (ONOOH/ONOO−) and superoxide (HO2•/O2•−). Cyclic hydroxylamines, which upon oxidation yie
Externí odkaz:
https://doaj.org/article/5b54eaf15cc14fd3baf2310c3c4213b6
Publikováno v:
Antioxidants, Vol 11, Iss 40, p 40 (2022)
Antioxidants
Antioxidants; Volume 11; Issue 1; Pages: 40
Antioxidants
Antioxidants; Volume 11; Issue 1; Pages: 40
There is a considerable need for methods that allow quantitative determination in vitro and in vivo of transient oxidative species such as peroxynitrite (ONOOH/ONOO−) and superoxide (HO2•/O2•−). Cyclic hydroxylamines, which upon oxidation yie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a758582b10adb834af34b741b5b92979
https://www.mdpi.com/2076-3921/11/1/40
https://www.mdpi.com/2076-3921/11/1/40
Autor:
Sara Goldstein, Amram Samuni
Publikováno v:
Free Radical Biology and Medicine. 160:837-844
In vivo, nitroxide antioxidants distribute within minutes throughout all tissues, but are reduced to their respective hydroxylamines due to the cellular reducing environment, which apparently limits their application. To distinguish their antioxidati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1c7ebedb54676b7ae9bd2e97cfa675
https://doi.org/10.1016/j.freeradbiomed.2020.08.022
https://doi.org/10.1016/j.freeradbiomed.2020.08.022
Publikováno v:
Free radical biologymedicine. 177
Asthma is characterized by airway inflammation, hyper-responsiveness, symptoms of dyspnea, wheezing and coughing. In most patients, asthma is well controlled using inhaled corticosteroids and bronchodilators. A minority of patients with asthma develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5814af75e45b0d4d38001eebcef7c116
https://pubmed.ncbi.nlm.nih.gov/34678420
https://pubmed.ncbi.nlm.nih.gov/34678420
Publikováno v:
Free radical biologymedicine. 171
Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease with a poor prognosis and limited treatment options. Oxidative and nitrosative stress is implicated as one of the main pathogenic pathways in IPF. The rationale for the use of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8c21e1e272db03a166416fd5b561e3
https://pubmed.ncbi.nlm.nih.gov/33989760
https://pubmed.ncbi.nlm.nih.gov/33989760
Publikováno v:
The Journal of Physical Chemistry A. 122:3747-3753
Hydroxamic acids (RC(O)NHOH) form a class of compounds that display interesting chemical and biological properties The chemistry of RC(O)NHOH) is associated with one- and two-electron oxidations forming the respective nitroxide radical (RC(O)NHO•)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897d435e0b6fcbd24ebbc6752198ebf4
https://doi.org/10.1021/acs.jpca.8b02300
https://doi.org/10.1021/acs.jpca.8b02300
Publikováno v:
Free Radical Biology and Medicine. 108:832-839
The peroxidative activity of horseradish peroxidase (HRP) undergoes progressive inactivation while catalyzing the oxidation of nitrite by H2O2. The extent of inactivation increases as the pH increases, [nitrite] decreases or [H2O2] increases, and is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f473359c9914439466c2d238142047fe
https://doi.org/10.1016/j.freeradbiomed.2017.05.010
https://doi.org/10.1016/j.freeradbiomed.2017.05.010
Publikováno v:
Free Radical Biology and Medicine. 101:491-499
Stable nitroxide radicals have multiple biological effects, although the mechanisms underlying them are not fully understood. Their protective effect against oxidative damage has been mainly attributed to scavenging deleterious radicals, oxidizing re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::490867e3e4e7005e7d060fc895b9cace
https://doi.org/10.1016/j.freeradbiomed.2016.10.534
https://doi.org/10.1016/j.freeradbiomed.2016.10.534
Publikováno v:
Biochimica et biophysica acta. General subjects. 1863(11)
Background Nitroxide antioxidants (RNO•) protect from injuries associated with oxidative stress. Tyrosine residues in proteins are major targets for oxidizing species giving rise to irreversible cross-linking and protein nitration, but the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d99bc423882a6954d99280297b726396
https://pubmed.ncbi.nlm.nih.gov/31356821
https://pubmed.ncbi.nlm.nih.gov/31356821
Publikováno v:
A108. PATHOPHYSIOLOGY IN DIFFUSE PARENCHYMAL LUNG DISEASES.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be07ed066f2768159a86b2f500a7d232
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2581
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2581