Impact of TNF-α Gene Polymorphisms on Pancreatic and Non-Small Cell Lung Cancer-Induced Cachexia in Adult Egyptian Patients: A Focus on Pathogenic Trajectories

Autor: Rana Yehia, Mona Schaalan, Dalaal M. Abdallah, Amr S. Saad, Neven Sarhan, Samira Saleh

Publikováno v: Frontiers in Oncology, Vol 11 (2021)

BackgroundCachexia is a frequent syndrome in pancreatic and non-small cell lung (NSCL) cancer patients. The storm of cancer-induced inflammatory cytokines, in particular TNF-α, is a crucial pathogenic mechanism. Among the molecular alterations accus

Externí odkaz: https://doaj.org/article/7ed54086acbd41d3b31cb39c272256d0

Prognostic utility of lncRNAs (LINC00565 and LINC00641) as molecular markers in glioblastoma multiforme (GBM)

Autor: Rehab G Amer, Lobna Ezz El Arab, Dalia Abd El Ghany, Amr S Saad, Nermean Bahie-Eldin, Menha Swellam

Publikováno v: Journal of Neuro-Oncology. 158:435-444

Background and aim Glioblastoma multiforme (GBM) is primary brain tumor grade IV characterized by fast cell proliferation, high mortality and morbidity and most lethal gliomas. Molecular approaches underlying its pathogenesis and progression with dia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4474dc899e4e43f736c9a4121a731612
https://doi.org/10.1007/s11060-022-04030-7

Resource Oriented Decision Making for Treatment of Metastatic Colorectal Cancer (mCRC) in a Lower-Middle Income Country: Egyptian Foundation of Medical Sciences (EFMS) Consensus Recommendations 2020

Autor: Noha Rashad, Mohamed Abdulla, Mohamed Farouk, Yasser Elkerm, Salem Eid Salem, Maha Yehia, Amr S Saad, Ahmed Hassan Abdel Aziz, Ghada Refaat, Ibrahim Awad, Maha ElNaggar, Khaled Kamal, Basel Refky, Mohamed Abdelkhalek, Ahmed Touny, Loay Kassem, Emad Shash, Abdelhay A Abdelhay, Bahaa Eldin Mahmoud, Karima Oualla, Nesrine Chraiet, Hussein AwadElkarim H Maki, Yasser A Kader

Publikováno v: Cancer management and research. 14

Noha Rashad,1 Mohamed Abdulla,2 Mohamed Farouk,3 Yasser Elkerm,4 Salem Eid Salem,5 Maha Yahia,5 Amr S Saad,6 Ahmed Hassan Abdel Aziz,6 Ghada Refaat,6 Ibrahim Awad,7 Maha ElNaggar,8 Khaled Kamal,6 Basel Refky,9 Mohamed Abdelkhalek,9 Ahmed Touny,10 Loa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3edf3786c534e8519cbf22fcacf2db38
https://pubmed.ncbi.nlm.nih.gov/35250310

Ongoing Mutations in Polytreated Metastatic Cancer Patients May Create a New Chance of Treatment with Unexpected Drugs

Autor: Mahmoud Salah Abdelsalam, Amr S Saad, Amr Elsebaei, Mahmoud Ellithy

Publikováno v: Journal of Cancer Therapy. :839-849

Objectives: In this study molecular/genomic characteristics were done on new tissue biopsies taken from Egyptian patients with refractory metastatic solid tumors aiming for two end points: To figure out a personalized treatment and to find the percen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ac1629e123d2042152034b56a97206c
https://doi.org/10.4236/jct.2018.911069

Doxorubicin-loaded nanoparticles for patients with advanced hepatocellular carcinoma after sorafenib treatment failure (RELIVE): a phase 3 randomised controlled trial

Autor: Inmaculada Ales, Hakan Harputluoglu, Marc Peeters, Jean-Marc Phelip, G. Pelletier, Zsuzsanna Kahan, Alice Gangloff, Fadi Farhat, Imam Waked, Luc Lasser, René Gerolami, Giovanni Luca, Thomas Berg, Julie Le Boulicaut, Jean-Pierre Zarski, Ivan Borbath, Wolfgang Sieghart, Ozlem Ata, Howard Ozer, Julie Vincent, Thierry Fontanges, Bartomeu Massuti, Christos Galanopoulos, Mohammed El Kassas, Audrey Molé, Imam Wakid, Philippe Merle, Nasr El Lahlouby, Andreas Maieron, Marilyne Debette-Gratien, Antonio Cubillo, György Bodoky, Sylvain Manfredi, Faiza Khemissa-Akouz, Jawad Makarem, Jean-Frédéric Blanc, Ahmet Coker, Carmen Guillén, Massimo Colombo, Michael Schultheiß, Joerg Trojan, Yann Touchefeu, Isabelle Ollivier-Hourmand, François Habersetzer, Vlad Ratziu, Amr Abdel, Amr S Saad, Miguel Marín, Magdolna Dank, Mohamed Bouattour, Hélène Regnault, Jean-Didier Grangé, Pierluigi Toniutto, Hanaa Kohail, Sameh Shamaa, Carine Richou, Erdem Goker, Eric Nguyen-Khac, Oscar Alabiso, G.-P. Pageaux, Andrea Casadei-Gardini, Moses Raj, Alexander Zipprich, Henning Wege, Ilkay Tugba, Aurore Baron, Victor Navarro, Domenico Amoroso, Issam Chehade, Nashat Gabrail, Pierre Attali, Barbara Dauvois, Stefano Tamberi, Driffa Moussata, Angela Buonadonna, Emiliano Tamburini, Muhammet Ali, Armand Abergel, Albert Tran, Suayib Yalcin, Ursula Ehmer, Hermini Manzano, Jean Delwaide, Andrés Muñoz, Carlos López, Jean-Pierre Bronowicki, Zsolt Horváth, Alper Sevinc, Gloria Sánchez, Ralph Hauke, Gabriele Luppi, Bérangère Vasseur, Nelson S. Yee

Publikováno v: The Lancet Gastroenterology & Hepatology
The Lancet Gastroenterology & Hepatology, 2019, 4 (6), pp.454-465. ⟨10.1016/S2468-1253(19)30040-8⟩
The Lancet Gastroenterology and Hepatology
The Lancet Gastroenterology and Hepatology, Elsevier, 2019, 4 (6), pp.454-465. ⟨10.1016/S2468-1253(19)30040-8⟩
The lancet. Gastroenterology & hepatology, Vol. 4, no.6, p. 454-465 (2019)

Summary Background Cytotoxic chemotherapy is generally ineffective in patients with hepatocellular carcinoma. We assessed the intravenous perfusion of doxorubicin-loaded nanoparticles in patients with hepatocellular carcinoma in whom previous sorafen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc13cf233d3e2a20a7e1e6a49e380d68
https://hal-amu.archives-ouvertes.fr/hal-02262527