Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Amr El-Karef"'
Publikováno v:
Mansoura Medical Journal. 50:163-172
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a2c07ff9517930b98a58b0879e4c2e4
https://doi.org/10.21608/mjmu.2021.105430.1051
https://doi.org/10.21608/mjmu.2021.105430.1051
Publikováno v:
Life sciences. 277
Aims The current study aims to investigate the role of the key effector cytokines produced by CD4+T cells in the pathogenesis of Con A-induced liver injury in mice and testing whether etanercept can be repurposed to differentially regulate these cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d554397431943932d1357b4fffbfc4
https://pubmed.ncbi.nlm.nih.gov/34004252
https://pubmed.ncbi.nlm.nih.gov/34004252
Autor:
Amr El-Karef, Nashwa M Abu-Elsaad
Publikováno v:
Inflammation. 41:221-231
Luteolin is a major component of many medicinal plants and traditional medicines. The current study aims at testing its protective effect against high-carbohydrate/high-fat (HCHF) diet-induced cardiac dysfunction in rats. Male Wistar rats were divide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2c34cfbf35a2e3ceef1f0bb89747ac
https://doi.org/10.1007/s10753-017-0680-8
https://doi.org/10.1007/s10753-017-0680-8
Autor:
Hany I. Kenawy, Randa A. Zaghloul, Amr El-Karef, Nehal M. Elsherbiny, Laila A. Eissa, Mamdouh M. El-Shishtawy
Publikováno v:
Life Sciences. 185:114-125
Aims Wnt3a and Wnt5a are ligands orchestrating the canonical and non-canonical pathways, respectively, with involvement in hepatocellular carcinoma (HCC). Hesperidin (HP) is a natural product found in citrus fruits and reputed for its antitumor activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb1f6e2794fec6cf6444a08e71eb2d2f
https://doi.org/10.1016/j.lfs.2017.07.026
https://doi.org/10.1016/j.lfs.2017.07.026
Publikováno v:
International immunopharmacology. 75
AIMS Immune mediated liver injury includes activation of different immune pathways that requires various modalities to control their consequences. The current study involves evaluation of retinoic acid (RA) modulatory effects on immune responses indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa2d78d3b3510e5c5f70cac41ee9b3d
https://pubmed.ncbi.nlm.nih.gov/31419710
https://pubmed.ncbi.nlm.nih.gov/31419710
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 129
Treatment of many inflammatory diseases involves a chronic use of NSAIDs in large doses increasing acute kidney injury risk. This study was designed to evaluate a potential renoprotective effect of Gum Acacia (GA) on diclofenac (DICF) induced nephrot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870d6705db92c6f1281b7582978bf5b4
https://pubmed.ncbi.nlm.nih.gov/31042592
https://pubmed.ncbi.nlm.nih.gov/31042592
Publikováno v:
European Journal of Pharmacology. 789:362-369
Vitamin D was found to be involved in liver fibrosis modulation through binding to its receptor (VDR) halting many fibrotic pathways. Targeting vitamin D-VDR axis using vitamin D analogs may represent an efficient strategy for liver fibrosis treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba201e9267d931d5f128e22d3ef3e97e
https://doi.org/10.1016/j.ejphar.2016.07.052
https://doi.org/10.1016/j.ejphar.2016.07.052
The heat shock protein 90 inhibitor, 17-AAG, attenuates thioacetamide induced liver fibrosis in mice
Publikováno v:
Pharmacological Reports. 68:275-282
Heat shock protein 90 (Hsp90) is proposed to be involved in liver disorders. This study was conducted to test effect of 17-N-allylamino-17-demethoxygeldanamycin (17-AAG), an inhibitor of Hsp90, on attenuating thioacetamide induced liver fibrosis in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede96c4032ee2c87a39e6c7382eee86b
https://doi.org/10.1016/j.pharep.2015.08.015
https://doi.org/10.1016/j.pharep.2015.08.015
Autor:
Amr El-Karef, Nashwa M Abu-Elsaad
Publikováno v:
Pharmacological reports : PR. 71(4)
The management of nonalcoholic steatohepatitis (NASH) is still a crosstalk so the current study was designed to evaluate the effect of different luteolin doses on an experimental model of NASH and to elucidate novel anti-inflammatory pathways underly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e84d2af2b332bd84f66eda3b651e4928
https://pubmed.ncbi.nlm.nih.gov/31207429
https://pubmed.ncbi.nlm.nih.gov/31207429
Publikováno v:
Journal of Medicinal Food. 18:950-959
Probiotics and antioxidants have a definite improving effect in cardiovascular diseases. This study aims at mitigating doxorubicin toxicity on cardiac function through consuming a functional food. Five groups of adult male Sprague-Dawley rats were us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f0ec774302ec301477a05db5ee520e
https://doi.org/10.1089/jmf.2014.0104
https://doi.org/10.1089/jmf.2014.0104