Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Amr A.A. Mahmoud"'
Autor:
Mona F. Mahmoud, Hoda M.S. Ahmed, Samar G. Mohamed, Islam A.A.E.-H. Ibrahim, Amr A.A. Mahmoud, Wael S. Ibrahim, Asmaa M. Rezk
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 100:68-77
We aimed to investigate the acute and chronic effects of carvedilol on insulin resistance in high-fructose, high-fat diet (HFrHFD) – fed mice and the implication of the β-arrestin2 pathway. The acute effect of carvedilol (10 mg/kg, i.p.) on glucos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044333218e1783b25152a3a747eab5fd
https://doi.org/10.1139/cjpp-2021-0299
https://doi.org/10.1139/cjpp-2021-0299
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics. 25:354-363
Background:Insulin resistance (IR) is a well-known risk factor for cardiovascular complications. This study aimed to investigate the effect of a dietary model of IR in mice on cardiac remodeling, cardiac β-arrestin2 signaling, and the protective eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::053bd80767c657a6f79be4dc0666ba5e
https://doi.org/10.1177/1074248420905683
https://doi.org/10.1177/1074248420905683
Publikováno v:
Pharmacology. 106(7-8)
Introduction: Pioglitazone is a thiazolidinedione oral antidiabetic agent. This study aimed to investigate the effects of pioglitazone as insulin sensitizer on β-arrestin2 signaling in classical insulin target tissues. Methods: Experiments involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08632f728e6a8ff95f48f04e23bd6cb6
https://pubmed.ncbi.nlm.nih.gov/34082428
https://pubmed.ncbi.nlm.nih.gov/34082428
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 394(5)
Aluminum is well recognized as a nephrotoxic agent. Its hazardous effects arise from the high risk of daily exposure. The consumption of fructose also represents a critical health issue that might negatively impact different organs, including the kid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6a61b52f6849f51c90ffeb35b7b45a
https://pubmed.ncbi.nlm.nih.gov/33165681
https://pubmed.ncbi.nlm.nih.gov/33165681
Publikováno v:
European journal of pharmacology. 879
Metabolic Syndrome (MetS) increases the risk of developing type 2 diabetes mellitus and cardiovascular complications. The crosstalk between the hypothalamus and periphery is vital for regulating food intake and energy homeostasis. However, it is impa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3cd0db219a9fc8b43b70a70f0ccf84
https://pubmed.ncbi.nlm.nih.gov/32360834
https://pubmed.ncbi.nlm.nih.gov/32360834
Publikováno v:
Diabetesmetabolic syndrome. 14(5)
Background and aims Diabetes Mellitus (DM) and depression occur comorbidly and share some pathophysiological mechanisms. The course of depression in patients with the two conditions is severe. Treatment of depression in diabetic patients requires spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36aaaaba01e8f92a2ca635763a167a01
https://pubmed.ncbi.nlm.nih.gov/32673838
https://pubmed.ncbi.nlm.nih.gov/32673838
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 393(10)
Insulin resistance is a worldwide health problem. This study investigated the acute effects of eicosapentanoic acid (EPA) on glucose homeostasis focusing on the role of free fatty acid receptor 1 (FFAR1) and the chronic effects of fish oil omega-3 fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb179b847dbe3fe87abe3ac56b400e02
https://pubmed.ncbi.nlm.nih.gov/32388601
https://pubmed.ncbi.nlm.nih.gov/32388601
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 96:569-576
Therapeutic interventions for liver fibrosis are still limited due to the complicated molecular pathogenesis. Renin–angiotensin system (RAS) seems to contribute to the development of hepatic fibrosis. Therefore, we aimed to examine the effect of RA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1e9eaaa5715168e7471a310209cf44e
https://doi.org/10.1139/cjpp-2017-0728
https://doi.org/10.1139/cjpp-2017-0728
Publikováno v:
Life Sciences. 286:120055
Aims β-Arrestin2 signaling has emerged as a promising therapeutic target for the management of insulin resistance and related complications. Moreover, recent studies have shown that certain G protein-coupled receptor (GPCR) ligands can modulate β-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4fa86cb8db05021f6b1a0243668289
https://doi.org/10.1016/j.lfs.2021.120055
https://doi.org/10.1016/j.lfs.2021.120055
Publikováno v:
Zagazig Journal of Pharmaceutical Sciences. 26:55-66
Cancer is a broad term used to describe a large number of diseases characterized by uncontrolled cell proliferation that leads to tumor production. Cancer is associated with mutations in genes controlling proliferation, oxidative stress and other mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f0a805d0ea4d3b9b06c40934ee337aa
https://doi.org/10.21608/zjps.2017.38141
https://doi.org/10.21608/zjps.2017.38141