The Circulating Micro-RNAs (−122, −34a and −99a) as Predictive Biomarkers for Non-Alcoholic Fatty Liver Diseases

Autor: Somia Mokabel Mohamed, Samia T. Ali, Mahmoud H. Allam, Shimaa Abdelsattar, Mohamed Abdel-Samiee, Hatem Rabie, Amr A. Elshormilisy, Nessren Mohamed Bahaa EL-Deen, Olfat Hendy, Amr El Fouly, Nashwa Abdelmotelb

Publikováno v: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 12:2715-2723

Background It remains essential for patient safety to develop non-invasive diagnostic tools to diagnose non-alcoholic fatty liver rather than invasive techniques. Aim Our case-control study was to address the value of circulating miRNAs as a potentia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ae17ddd038ce5a6a46d1804753a4e56
https://doi.org/10.2147/dmso.s231321

Plasminogen activator inhibitor-1 gene polymorphism as a risk factor for vascular complications in type 2 diabetes mellitus

Autor: Waseem M. Gaber, Amr A. Elshormilisy, Samia T. Ali, Fatma A. Khalaf, Hatem R. Ibrahim, Hanan M Bedair, Maha M Allam

Publikováno v: Egyptian Journal of Medical Human Genetics, Vol 20, Iss 1, Pp 1-13 (2019)

Background Diabetes mellitus (DM) can lead to microvascular and macrovascular damages through hyperglycemia that is the main cause of diabetic complications. Other factors such as hypertension, obesity, and hyperlipidemia may worsen or accelerate the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d14906eac377d88525ad4fc737248b3
http://link.springer.com/article/10.1186/s43042-019-0018-1

Role of resistin, IL-6 and NH2-terminal portion proBNP in the pathogenesis of cardiac disease in type 2 diabetes mellitus

Autor: Mohamed Hamdy Torky, Karema A. Diab, Sania Ali Yehia, Samar Ghanem, Hany A. A. Elbasyouni, Mohamed Abdel-Samiee, Ahmed Gaafar, Somia Mokabel Mohamed, Ghada Mohamed Mohamed Salah Eldin, Dalia M Elsabaawy, Amr A. Elshormilisy, Samah Mohammed Awad

Publikováno v: BMJ Open Diabetes Research & Care

IntroductionEpidemiological and genetic studies have recorded the association between proinflammatory cytokines and the development of insulin resistance, diabetes, and cardiovascular disease. The role of interleukin 6 (IL-6), NH2-terminal portion pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6114c2a188a6d0ad15a9c25ca5100d
http://europepmc.org/articles/PMC7523202

The Role of Resistin, IL-6 and NH2-Terminal Portion ProBNP in Pathogenesis of Cardiac Disease in Type 2 Diabetes Mellitus

Autor: Ghada Mohamed Mohamed Salah Eldin, Karema A. Diab, Samah Mohammed Awad, Sania Ali Yehia, Mohamed Hamdy Torky, Samar Ghanem, Ahmed Gaafar, Dalia M Elsabaawy, Amr A. Elshormilisy, Somia Mokabel Mohamed, Mohamed Abdel-Samiee

Publikováno v: SSRN Electronic Journal.

Background: The role of interleukin-6 (IL-6), Nt-pro BNP and resistin in the pathogenesis of heart disease in type 2 diabetic is still a matter of controversy. The current study aimed to declare the association between circulating levels of resistin,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::28a16f80adfee509685a813c93445103
https://doi.org/10.2139/ssrn.3521418

Metformin suppresses LRG1 and TGFβ1/ALK1-induced angiogenesis and protects against ultrastructural changes in rat diabetic nephropathy.

Autor: Mohammad HMF; Department of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt; Central Lab., Center of Excellence in Molecular and Cellular Medicine (CEMCM), Faculty of Medicine, Suez Canal University, Ismailia, Egypt., Galal Gouda S; Department of Histology and cell Biology, College of Medicine, Suez Canal University, Ismailia 41522, Egypt., Eladl MA; Department of Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah 27272, United Arab Emirates., Elkazaz AY; Biochemistry and Molecular Biology Department, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt; Biochemistry and Molecular Biology Department, Faculty of Medicine, Portsaid University, Portsaid, Egypt., Elbayoumi KS; Department of Human Anatomy and Embryology, Faculty of Medicine, Mansoura University, Mansoura, Egypt; Department of Basic medical Sciences, Ibn Sina University for Medical Sciences, Amman 11104, Jordan., Farag NE; Department of Physiology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt; Department of Physiology, College of Medicine, Taif University, Taif 21974, Saudi Arabia., Elshormilisy A; Internal Medicine Department, Faculty of Medicine, Helwan University, Egypt., Al-Ammash BB; Department of Pharmaceutical Care Services, King Fahad hospital, Ministry of health, Medina, Saudi Arabia., Hegazy A; Department of Clinical Pathology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt., Abdelkhalig SM; Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, Riyadh, Saudi Arabia., Mohamed AS; Faculty of Public Health and Tropical Medicine, Jazan University, Jazan, Saudi Arabia., El-Dosoky M; Department of Neurosciences Technology, College of Applied Medical Sciences in Jubail, Imam Abdulrahman Bin Faisal University, Jubail 34221, Saudi Arabia. Electronic address: mesalama@iau.edu.sa., Zaitone SA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt. Electronic address: Sawsan_zaytoon@pharm.suez.edu.eg.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Feb; Vol. 158, pp. 114128. Date of Electronic Publication: 2022 Dec 14.