Zobrazeno 1 - 10
of 962
pro vyhledávání: '"Ampk signaling"'
Autor:
Sagar R Barge, Anupam Bhattacharya, Arun Kumar, Sushmita Das, Tulsi Joishy, Ashis K Mukherjee, Maloyjo Joyraj Bhattacharjee, Mojibur R Khan
Publikováno v:
Food Frontiers, Vol 5, Iss 4, Pp 1642-1657 (2024)
Abstract Functional foods, such as fermented bamboo shoots, have a long history of consumption among the ethnic communities in northeast India. These locally fermented bamboo shoots contain a wealth of beneficial microbes and metabolites that can hel
Externí odkaz:
https://doaj.org/article/8fdc03ac44e54a589845ddeda4fe0389
Publikováno v:
Poultry Science, Vol 103, Iss 12, Pp 104268- (2024)
ABSTRACT: Mule ducks accumulate a large amount of fat in their livers when fed high-energy feed, which is predominantly used for producing fatty livers. Nevertheless, there is limited research on the molecular mechanisms underlying the formation of f
Externí odkaz:
https://doaj.org/article/ce4099cb919d434e80021d4bebe05ad0
Publikováno v:
Renal Failure, Vol 46, Iss 1 (2024)
Objective Liraglutide, a glucagon-like peptide-1 receptor agonist, has been shown to regulate blood sugar and control body weight, but its ability to treat obesity-related nephropathy has been poorly studied. Therefore, this study was designed to obs
Externí odkaz:
https://doaj.org/article/ce39ac4468a24c868423c11c1d2c3624
Autor:
Kui Chen, Hao-jie Jin, Zi-heng Wu, Bao-fu Zhang, Jun Wu, Zi-yi Huang, Ying-peng Huang, Xin-wu Lu, Xiang-tao Zheng
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-13 (2024)
Abstract Background Vascular calcification (VC) is a complication in diabetes mellitus (DM) patients. Osteogenic phenotype switching of vascular smooth muscle cells (VSMCs) plays a critical role in diabetes-related VC. Mitophagy can inhibit phenotype
Externí odkaz:
https://doaj.org/article/671dcee356c64e7a96f827e21f67e967
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e34717- (2024)
Objective: To explore the pharmacological mechanism of the effect of fraxetin in treating acute myeloid leukemia (AML) by the network pharmacology method combined with experimental validation. Methods: The targets of fraxetin were identified through
Externí odkaz:
https://doaj.org/article/b2b1059f51ef4bc7b35d4e24e320452d
Publikováno v:
Poultry Science, Vol 103, Iss 7, Pp 103818- (2024)
ABSTRACT: Mule ducks tend to accumulate abundant fat in their livers via feeding, which leads to the formation of a fatty liver that is several times larger than a normal liver. However, the mechanism underlying fatty liver formation has not yet been
Externí odkaz:
https://doaj.org/article/e5b7ffcf87f44a868b6f0d56f511eb58
Publikováno v:
Thoracic Cancer, Vol 15, Iss 4, Pp 286-298 (2024)
Abstract Background GTPase immunity‐associated protein 7 (GIMAP7) has been previously recognized as a prognostic marker in pan‐cancer. Our objective was to explore the function of GIMAP7 in the progression of lung adenocarcinoma (LUAD). Methods G
Externí odkaz:
https://doaj.org/article/859d0d5b32a34823953b8a2559e0bf9b
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract AXIN1, has been initially identified as a prominent antagonist within the WNT/β-catenin signaling pathway, and subsequently unveiled its integral involvement across a diverse spectrum of signaling cascades. These encompass the WNT/β-cateni
Externí odkaz:
https://doaj.org/article/04b0a10597f34fe59c66d9de2fd66b0c
Publikováno v:
Bangladesh Journal of Pharmacology, Vol 19, Iss 2 (2024)
Gemcitabine is a common first-line chemotherapy agent, but gemcitabine resistance is a clinical challenge for pancreatic ductal adenocarcinoma patients. Solute carrier 39A1 (SLCA39A1) as a zinc regulator presents a crucial function in the modulation
Externí odkaz:
https://doaj.org/article/a2afec6b680a49ca90735d859b415c31
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background and purposeAs a traditional Chinese medicine formula, Yangyinghuoxue Decoction (YYHXD) is used clinically for therapy of hepatic fibrosis. The pharmacological profile of YYHXD comprises multiple components acting on many targets and pathwa
Externí odkaz:
https://doaj.org/article/defdc1fa369d4689a4d48ce823d75ab7