Zobrazeno 1 - 10
of 1 140
pro vyhledávání: '"Ampk mtor"'
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 11, Pp 996-1005 (2024)
Abstract This study investigated the impact of LNP023 on the AMPK/mTOR signaling pathway in lupus nephritis (LN) and its effects on autophagy and oxidative stress. A mouse model of LN was established, and renal injury was confirmed by assessing vario
Externí odkaz:
https://doaj.org/article/111c76b3d8054310a7737b1e75310f58
Publikováno v:
Nutrition & Metabolism, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract Sepsis-induced myopathy (SIM) has been recognized as a critical risk factor for the development of acquired muscle weakness among patients in the intensive care unit. These individuals frequently encounter inadequate dietary intake and malnu
Externí odkaz:
https://doaj.org/article/486bd5f016f0401c8db44038c5af642e
Autor:
Xiaoqing Cheng, Yuqiong Dai, Baoling Shang, Shuting Zhang, Liting Lin, Qingguang Wu, Ruoting Zhan, Shengqing Li, Sijun Liu
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Danggui Shaoyao San (DSS), a frequently prescribed Chinese medicine formula, has demonstrated clinical efficacy in the treatment of Alzheimer’s disease (AD). This study aims to explore the differences in therapeutic effects of D
Externí odkaz:
https://doaj.org/article/ecfd09dee7dd46dfacb8d1e3a883a6ab
Autor:
Linquan Zhou, Chengcheng Zhang, Tengbin Shi, Dingwei Wu, Huina Chen, Jiaxin Han, Dehui Chen, Jinxin Lin, Wenge Liu
Publikováno v:
Materials Today Bio, Vol 29, Iss , Pp 101261- (2024)
The migration and differentiation of bone marrow mesenchymal stem cells (BMSCs) play crucial roles in bone repair processes. However, conventional scaffolds often lack of effectively inducing and recruiting BMSCs. In our study, we present a novel app
Externí odkaz:
https://doaj.org/article/d77a887077f74a80ab5f15195578d7dc
Autor:
Mengdi Chen, Congcong Zhang, Zewen Wu, Siwei Guo, Wenfa Lv, Jixuan Song, Beibei Hao, Jinhui Bai, Xinxin Zhang, Hongyan Xu, Guangjun Xia
Publikováno v:
Animal Bioscience, Vol 37, Iss 7, Pp 1156-1167 (2024)
Objective MicroRNAs (miRNAs) are endogenous non-coding RNAs that can play a role in the post-transcriptional regulation of mammalian preadipocyte differentiation. However, the precise functional mechanism of its regulation of fat metabolism is not fu
Externí odkaz:
https://doaj.org/article/56c9ddb6904649da8ca5d1b84a0f4085
Publikováno v:
Open Medicine, Vol 19, Iss 1, Pp 1376-414 (2024)
The malfunction of endothelial progenitor cells (EPCs) due to ox-LDL is a risk contributor for arteriosclerotic disease. Meanwhile, lycopene possesses anti-inflammatory and antioxidative qualities. This investigation aimed to determine if lycopene ca
Externí odkaz:
https://doaj.org/article/c3407c5ab5b94d93972a95be8c0fc007
Publikováno v:
Journal of Orthopaedic Translation, Vol 46, Iss , Pp 129-142 (2024)
Background: Age-related mandibular osteoporosis frequently causes loose teeth, difficulty eating, and disfiguration in elders. Bmi1−/− mice displaying accelerated skeletal aging represent a useful model for testing interventions against premature
Externí odkaz:
https://doaj.org/article/9884dc32d41f4ff8bd257cf7a23aa4bc
Publikováno v:
In Neuroscience 26 January 2025 565:91-98
Publikováno v:
European Journal of Histochemistry, Vol 68, Iss 4 (2024)
Restenosis is a pivotal factor that restricts the efficacy of coronary artery bypass grafting. Inhibition of vascular smooth muscle cells (VSMCs) proliferation can improve intimal hyperplasia and lumen stenosis. Irisin, a polypeptide secreted by musc
Externí odkaz:
https://doaj.org/article/7249dc26665e44fda35afbdd4726f1ab
Autor:
Xiaoping Ma, Aining Yang, Xiaoben Fan, Hong Liu, Yu Gu, Zhisheng Wang, Hongrui Guo, Jing Fang, Hengmin Cui, Liping Gou, Junliang Deng, Dongjie Cai, Zhicai Zuo
Publikováno v:
Heliyon, Vol 10, Iss 19, Pp e38026- (2024)
Objective: Resistin (RETN) is an adipocyte-specific hormone that participates in metabolism and modulates cellular inflammation. Our study aimed to assess the effects of RETN treatment on autophagy and the underlying molecular and biological mechanis
Externí odkaz:
https://doaj.org/article/c0d7ff242b5b4aabacbc0ac74e8e1551