Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Amour, Venter"'
Autor:
Lauren Philips, Madeleine Lourens, Lize van der Merwe, Amour Venter, Andreas H. Diacon, Sven O. Friedrich, Neil A. Martinson, Carmen C. Kleinhans
Publikováno v:
Tuberculosis. 116:17-21
Mycobacterial sputum culture is a key diagnostic and research tool.To compare mycobacterial culture outcomes of three sputum collection methods.We compared culture results within sets of three sputum samples collected from 18 HIV-infected adult tuber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ac26703a65df27cb60dd0145ab025a
https://doi.org/10.1016/j.tube.2019.03.008
https://doi.org/10.1016/j.tube.2019.03.008
Autor:
Robert S Wallis, Rodney Dawson, Sven O Friedrich, Amour Venter, Darcy Paige, Tong Zhu, Annette Silvia, Jason Gobey, Craig Ellery, Yao Zhang, Kathleen Eisenach, Paul Miller, Andreas H Diacon
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94462 (2014)
Sutezolid (PNU-100480) is a linezolid analog with superior bactericidal activity against Mycobacterium tuberculosis in the hollow fiber, whole blood and mouse models. Like linezolid, it is unaffected by mutations conferring resistance to standard TB
Externí odkaz:
https://doaj.org/article/1d2f4c6c83044d40877fbbf4225b55e9
Autor:
Devinder Kaur, Daniela Maria Cirillo, Amour Venter, Nacer Lounis, Beverly Metchock, Koné Kaniga, Sven Hoffner, Nazir Ahmed Ismail, Gaby E. Pfyffer
Publikováno v:
Journal of Clinical Microbiology. 54:2956-2962
The aim of this study was to establish standardized drug susceptibility testing (DST) methodologies and reference MIC quality control (QC) ranges for bedaquiline, a diarylquinoline antimycobacterial, used in the treatment of adults with multidrug-res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db7044b9457818df67b277e5fec7598
https://doi.org/10.1128/jcm.01123-16
https://doi.org/10.1128/jcm.01123-16
Autor:
Jane Hutchings, Christo van Niekerk, Florian von Groote-Bidlingmaier, Gregory Symons, Andreas H. Diacon, Robert Schall, Daniel Everitt, Amour Venter, Mendel Carl M, Peter R. Donald, Divan Aristo Burger, Rodney Dawson
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 191:943-953
New regimens to shorten tuberculosis treatment and manage patients with drug-resistant tuberculosis who are infected with HIV are urgently needed. Experimental and clinical evidence suggests that the new drugs bedaquiline (B) and pretomanid (Pa), com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c08c5116991ab88803767f8a0bfba38
https://doi.org/10.1164/rccm.201410-1801oc
https://doi.org/10.1164/rccm.201410-1801oc
Autor:
Norbert, Heinrich, Rodney, Dawson, Jeannine, du Bois, Kim, Narunsky, Gary, Horwith, Andrew J, Phipps, Carol A, Nacy, Rob E, Aarnoutse, Martin J, Boeree, Stephen H, Gillespie, Amour, Venter, Sonja, Henne, Andrea, Rachow, Patrick P J, Phillips, Michael, Hoelscher, Andreas H, Diacon, Alphonse, Okwera
Publikováno v:
Journal of Antimicrobial Chemotherapy, 70, 5, pp. 1558-66
Journal of Antimicrobial Chemotherapy, 70, 1558-66
Journal of Antimicrobial Chemotherapy, 70, 1558-66
Objectives SQ109, an asymmetrical diamine, is a novel anti-TB drug candidate. This first study in patients was done to determine safety, tolerability, pharmacokinetics and bacteriological effect of different doses of SQ109 alone and in combination wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c2bca9dfa86332c36c960317059ca2
https://doi.org/10.1093/jac/dku553
https://doi.org/10.1093/jac/dku553
Autor:
Florian von Groote-Bidlingmaier, Anne-Marie Demers, Amour Venter, Peter R. Donald, Lize van der Merwe, Andreas H. Diacon
Publikováno v:
Tuberculosis. 94:690-694
Summary Time to culture positivity (TTP) in liquid medium is now widely available as a measure of viable mycobacterial sputum load. TTP correlates well with and could replace colony-forming unit (CFU) counting in studies of antituberculosis drug effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef65130652a1b8121041774d99c7fb6e
https://doi.org/10.1016/j.tube.2014.08.015
https://doi.org/10.1016/j.tube.2014.08.015
Autor:
W. Henry Boom, Sara A. Debanne, Phalkun Chheng, Charles A. Peloquin, Amour Venter, Bonnie Thiel, Jeannine Du Bois, Elana van Brakel, Jennifer Furin, Abdullah Alsultan, John L. Johnson, Andreas H. Diacon
AZD-5847 is a new oxazolidinone derivative under development for the treatment of tuberculosis (TB). Here we describe the population pharmacokinetics (PK) of AZD-5847 in patients with tuberculosis based on a recently completed phase II study. The stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8500bf92c4c0b1515ffdac793481b9ae
https://europepmc.org/articles/PMC5610519/
https://europepmc.org/articles/PMC5610519/
Autor:
Florian von Groote-Bidlingmaier, Andreas H. Diacon, Anne-Marie Demers, Peter R. Donald, Amour Venter, Lize van der Merwe
Publikováno v:
Tuberculosis. 94:148-151
Time to liquid culture positivity (TTP) is a technically accessible and widely available measure of viable mycobacterial load in sputum samples. We describe the ability of TTP to predict colony forming unit counts of Mycobacterium tuberculosis from s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ad2f8159b2d7e6a79d68b6c30677bb
https://doi.org/10.1016/j.tube.2013.12.002
https://doi.org/10.1016/j.tube.2013.12.002
Autor:
Florian von Groote-Bidlingmaier, Ann M. Ginsberg, Piet J. Becker, Amour Venter, Erica Egizi, Andreas H. Diacon, Mendel Carl M, Rodney Dawson, Peter R. Donald, Gregory Symons, Almari Conradie, Helen Winter, Ngozi Erondu
Publikováno v:
Antimicrobial Agents and Chemotherapy. 57:2199-2203
Bedaquiline is a new antituberculosis agent targeting ATP synthase. This randomized, double-blinded study enrolling 68 sputum smear-positive pulmonary tuberculosis patients evaluated the 14-day early bactericidal activity of daily doses of 100 mg, 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff907d8ea7df3ece9dcbc6de50afd85
https://doi.org/10.1128/aac.02243-12
https://doi.org/10.1128/aac.02243-12
Autor:
Amour Venter, Norbert Heinrich, Rodney Dawson, Catharina Boehme, Alimuddin Zumla, Andreas H. Diacon, Martin J. Boeree, Patrick P. J. Phillips, Andrea Rachow, Chacha Mangu, Anna Bateson, Timothy D. McHugh, Sven O. Friedrich, Kasha P. Singh, Stephen H. Gillespie, Robert D Hunt, Elmar Saathoff, Michael Hoelscher
Publikováno v:
Lancet Respiratory Medicine, 1, 6, pp. 462-70
Lancet Respiratory Medicine, 1, 462-70
Lancet Respiratory Medicine, 1, 462-70
SummaryBackgroundAn accurate biomarker is urgently needed to monitor the response to treatment in patients with pulmonary tuberculosis. The Xpert MTB/RIF assay is a commercially available real-time PCR that can be used to detect Mycobacterium-tubercu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c75671d3bf5e6aab4d8dfcc8f6abc395
https://hdl.handle.net/2066/125255
https://hdl.handle.net/2066/125255