Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Amoscanate"'
Autor:
Meshari Alazmi
Publikováno v:
Current Computer-Aided Drug Design. 16:772-785
Background: Schistosomiasis (snail fever/bilharzia), a disease caused by parasitic flatworms (schistosomes), infects millions of people worldwide. Aquaporins from these organisms were found to be a potent drug target. Introduction: We investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e872d37805bf0d3a9ec7586e8f1f5747
https://doi.org/10.2174/1573409915666191003124947
https://doi.org/10.2174/1573409915666191003124947
Intestinal trematodes, in spite of complex life cycles, retain a simplicity in transmission to man. They often exploit a niche in the food chain which is deeply embedded in cultural traditions; thus, interruption by simple avoidance becomes a practic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f3f1bc39663c9bda91acfb9fc72eb59
https://doi.org/10.1201/9781003068273-24
https://doi.org/10.1201/9781003068273-24
Publikováno v:
Archives of Toxicology. 67:120-125
Amoscanate, a substance which damages photoreceptors, was administered orally to Wistar rats in doses of 10, 40, and 125 mg/kg body weight once daily for 3 or 10 days. At both times electroretinographic, ophthalmological, and histopathological examin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd72b2d47ec3ae4a6cde65bacc58cec7
https://doi.org/10.1007/bf01973682
https://doi.org/10.1007/bf01973682
Autor:
Horst Zahner, Gereon Schares
Publikováno v:
Acta Tropica. 52:221-266
Eleven types/classes of compound with antifilarial activity were comparatively evaluated in Mastomys coucha infected with Litomosoides carinii, Acanthocheilonema viteae, Brugia malayi or B. pahangi. The paper deals with the efficacy of (i) predominan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce73fbca8e4e0b48edd2f3ae39569ff
https://doi.org/10.1016/0001-706x(93)90010-9
https://doi.org/10.1016/0001-706x(93)90010-9
A comprehensive 60-year review of antischistosomal drug discovery and development research in the People's Republic of China (P.R. China) is presented. In the 1950s, three antimonials were developed, which, compared to potassium antimony tartrate-the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e67bfc0fd561c77bdc19006374fea8c
https://doi.org/10.1016/s0065-308x(10)73009-8
https://doi.org/10.1016/s0065-308x(10)73009-8
Publikováno v:
Mutation research. 518(2)
The mutagenic activity of sulfoscanate (SSC) (4-isothiocyanate-4'-nitrodiphenyl sulphide) has been compared with that of the following reported drugs: (a) nitroscanate (NSC) (4-isothiocyanate-4'-nitrodiphenyl ether) which is a veterinary anthelmintic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb00654e8e30bcacba115f67982e4f49
https://pubmed.ncbi.nlm.nih.gov/12113767
https://pubmed.ncbi.nlm.nih.gov/12113767
Autor:
Sène, Mariama
La chimiothérapie est la méthode de lutte contre la schistosomose privilégiée par la plupart des programmes nationaux depuis une trentaine d'années. Les différentes molécules existantes sont décrites brièvement avec leurs avantages et leurs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______932::f75ee3998b3fcfea279cac4bf467957c
http://www.documentation.ird.fr/hor/fdi:010024018
http://www.documentation.ird.fr/hor/fdi:010024018
Publikováno v:
Acta tropica. 53(1)
Three recently introduced anthelmintic agents, the macrocyclic lactone, ivermectin, the amoscanate derivative CGP 6140 and the benzothiazole compound CGP 20376, were investigated for their in vitro modulatory effects on eosinophilic effector cells. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b09497cb692b3a2bccac4b6cb2bd7b0
https://pubmed.ncbi.nlm.nih.gov/8096107
https://pubmed.ncbi.nlm.nih.gov/8096107
Publikováno v:
Acta tropica. 51(3-4)
A variety of recently developed drugs, designed to be used in antifilarial chemotherapy, contain a thiocarbonylamide group as a common structural element. One group of these compounds is based on a 2-tert-butylbenzothiazole ring in which the carbonyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9424592bead6601e710e6755ec01c6
https://pubmed.ncbi.nlm.nih.gov/1359747
https://pubmed.ncbi.nlm.nih.gov/1359747
Publikováno v:
Parasitology research. 76(5)
Alterations in the fine structures of femaleBrugia spp. andLitomosoides carinii were investigated after in vivo treatment with curative doses of 4 compounds: CGP 20376 [2-tert-butyl-benzothiazole-5-methoxy-6-dithiocarbamic-S-(2-carboxyethyl)-ester],
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dbf6b1e352ef19ec84967a00da1c2fd
https://pubmed.ncbi.nlm.nih.gov/2352916
https://pubmed.ncbi.nlm.nih.gov/2352916