Výsledky vyhledávání - "Amos Nyathirombo"

Akademický článek

Onchocerca volvulus microfilariae in the anterior chambers of the eye and ocular adverse events after a single dose of 8 mg moxidectin or 150 µg/kg ivermectin: results of a randomized double-blind Phase 3 trial in the Democratic Republic of the Congo, Ghana and Liberia

Publikováno v: Parasites & Vectors, Vol 17, Iss 1, Pp 1-23 (2024)

Abstract Background After ivermectin became available, diethylcarbamazine (DEC) use was discontinued because of severe adverse reactions, including ocular reactions, in individuals with high Onchocerca volvulus microfilaridermia (microfilariae/mg ski

Externí odkaz: https://doaj.org/article/4ceb592513504c51851aa39437b4b9bd

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Akademický článek

Effect of a single dose of 8 mg moxidectin or 150 μg/kg ivermectin on O. volvulus skin microfilariae in a randomized trial: Differences between areas in the Democratic Republic of the Congo, Liberia and Ghana and impact of intensity of infection.

Autor: Didier Bakajika, Eric M Kanza, Nicholas O Opoku, Hayford M Howard, Germain L Mambandu, Amos Nyathirombo, Maurice M Nigo, Kambale Kasonia Kennedy, Safari L Masembe, Mupenzi Mumbere, Kambale Kataliko, Kpehe M Bolay, Simon K Attah, George Olipoh, Sampson Asare, Michel Vaillant, Christine M Halleux, Annette C Kuesel

Publikováno v: PLoS Neglected Tropical Diseases, Vol 16, Iss 4, p e0010079 (2022)

BackgroundOur study in CDTI-naïve areas in Nord Kivu and Ituri (Democratic Republic of the Congo, DRC), Lofa County (Liberia) and Nkwanta district (Ghana) showed that a single 8 mg moxidectin dose reduced skin microfilariae density (microfilariae/mg

Externí odkaz: https://doaj.org/article/1704f5ebb75340f7b6f1def82df12178

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O. volvulus microfilariae in the anterior chambers of the eye and ocular adverse events after a single dose of 8 mg moxidectin or 150 µg/kg ivermectin: Results of a randomized double-blind Phase 3 trial in the Democratic Republic of the Congo, Ghana and Liberia

Background After ivermectin became available, diethylcarbamazine (DEC) use was discontinued because of severe adverse reactions, including ocular reactions, in individuals with high O. volvulus microfilaridermia. Assuming long-term ivermectin use led

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2824fd9dce053cdb382d33d2235471e5
https://doi.org/10.21203/rs.3.rs-2879768/v1

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Single dose moxidectin versus ivermectin for Onchocerca volvulus infection in Ghana, Liberia, and the Democratic Republic of the Congo: a randomised, controlled, double-blind phase 3 trial

Publikováno v: Lancet (London, England)

Summary Background The morbidity and socioeconomic effects of onchocerciasis, a parasitic disease that is primarily endemic in sub-Saharan Africa, have motivated large morbidity and transmission control programmes. Annual community-directed ivermecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd77bf5e614d4080c469291a1e0a417
https://pubmed.ncbi.nlm.nih.gov/30319110

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