Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Amol M. Bhandare"'
Autor:
Amol M. Bhandare, Nicholas Dale
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
While central autonomic, cardiac, and/or respiratory dysfunction underlies sudden unexpected death in epilepsy (SUDEP), the specific neural mechanisms that lead to SUDEP remain to be determined. In this study, we took advantage of single-cell neurona
Externí odkaz:
https://doaj.org/article/06d2d4a17a1f4d5ca64639240a505cc4
Autor:
Joseph van de Wiel, Jonathan Cook, Nicholas Dale, Amol M. Bhandare, Robert T. R. Huckstepp, Louise Meigh, Sarbjit Nijjar
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
Breathing is highly sensitive to the PCO2 of arterial blood. Although CO2 is detected via the proxy of pH, CO2 acting directly via Cx26 may also contribute to the regulation of breathing. Here we exploit our knowledge of the structural motif of CO2-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57c79f75e03913a6690adc74d8728aa
http://wrap.warwick.ac.uk/142629/1/WRAP-connexin26-mediates-CO2-dependent-regulation-breathing-glial-cells-medulla-oblongata-Dale-2020.pdf
http://wrap.warwick.ac.uk/142629/1/WRAP-connexin26-mediates-CO2-dependent-regulation-breathing-glial-cells-medulla-oblongata-Dale-2020.pdf
Autor:
Komal Kapoor, Amol M. Bhandare, Melissa M.J. Farnham, Emma L. Braine, Paul M. Pilowsky, Terence J. O'Brien, Pablo M. Casillas-Espinosa, Kim L. Powell
Publikováno v:
Neuroscience. 350:23-38
The incidence of sudden unexpected death in epilepsy (SUDEP) is highest in people with chronic and drug-resistant epilepsy. Chronic spontaneous recurrent seizures cause cardiorespiratory autonomic dysfunctions. Pituitary adenylate cyclase-activating
Autor:
Joseph van de Wiel, Amol M. Bhandare, Nicholas Dale, Robert T. R. Huckstepp, Ingke Braren, Reno Roberts
The regulated excretion of CO2 during breathing is a key life-preserving homeostatic mechanism. In the rostral medulla oblongata, neurons in two nuclei -the retrotrapezoid nucleus (RTN) and the rostral medullary Raphe -have been proposed as central C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6323cc135b7f158935dce7d389b2dff6
https://doi.org/10.1101/492041
https://doi.org/10.1101/492041
Autor:
Melissa M.J. Farnham, Polina E. Nedoboy, Komal Kapoor, Paul M. Pilowsky, Suja Mohammed, Amol M. Bhandare
Publikováno v:
Neuroscience. 329:12-29
Microglia are present throughout the central nervous system (CNS) and express receptors for every known neurotransmitter. During inflammation, microglia change into a state that either promotes removal of debris (M1), or into a state that promotes so
Autor:
Polina E. Nedoboy, Paul M. Pilowsky, Suja Mohammed, Melissa M.J. Farnham, Amol M. Bhandare, K. Kapoor
Publikováno v:
Neuroscience. 317:162-172
Identification of neurons, and their phenotype, that are activated in response to specific stimuli is a critical step in understanding how neural networks integrate inputs to produce specific outputs. Here, we developed novel mouse monoclonal antibod
Publikováno v:
Journal of Ethnopharmacology. 171:121-124
Areca catechu Linn. (Arecaceae) nut is a popular folk remedy for the treatment of migraine in Kerala and Tamil Nadu states of India.This study was designed to investigate the effect of hydroalcoholic extract of A. catechu L. nut (ANE) treatment on mi
Publikováno v:
The Journal of Neuroscience. 35:2191-2199
Seizures are accompanied by cardiovascular changes that are a major cause of sudden unexpected death in epilepsy (SUDEP). Seizures activate inflammatory responses in the cardiovascular nuclei of the medulla oblongata and increase neuronal excitabilit
Autor:
Melissa M.J. Farnham, Paul M. Pilowsky, Polina E. Nedoboy, Suja Mohammed, Komal Kapoor, Amol M. Bhandare
Publikováno v:
The FASEB Journal. 30
Publikováno v:
Autonomic neuroscience : basicclinical. 198
Microglia are ubiquitously distributed throughout the central nervous system (CNS) and play a critical role in the maintenance of neuronal homeostasis. Recent advances have shown that microglia, never resting cells of the CNS, continuously monitor an