Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Amogh Kambalyal"'
Autor:
Amogh Kambalyal, John Edward Rouck, Aditi Das, Marjan De Mey, Parayil Kumaran Ajikumar, Bradley W. Biggs, William R. Arnold
Publikováno v:
Protein Expression and Purification. 132:60-67
Taxadiene-5α-Hydroxylase (CYP725A4) is a membrane-bound plant cytochrome P450 that catalyzes the oxidation of taxadiene to taxadiene-5α-ol. This oxidation is a key step in the production of the valuable cancer therapeutic and natural plant product,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a7469fdd6e3ffb37399be719835ae1
https://doi.org/10.1016/j.pep.2017.01.008
https://doi.org/10.1016/j.pep.2017.01.008
Publikováno v:
Biophysical Chemistry. :34-40
Thromboxane synthase (CYP5A1) is a non-classical cytochrome P450 (CYP) expressed in human platelets that mediates vascular homeostasis by producing thromboxane A2 (TXA2) through the isomerization of prostaglandin H2 (PGH2). A homology alignment of CY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32130ba270a76f1c0706b3b2742775dc
https://doi.org/10.1016/j.bpc.2015.03.002
https://doi.org/10.1016/j.bpc.2015.03.002
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 351:616-627
The endocannabinoids, anandamide (AEA) and 2-arachidonoylglycerol (2-AG), are arachidonic acid (AA) derivatives that are known to regulate human cardiovascular functions. CYP2J2 is the primary cytochrome P450 in the human heart and is most well known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7493c84a67a6f46e7efdf6a594e44f15
https://doi.org/10.1124/jpet.114.216598
https://doi.org/10.1124/jpet.114.216598
Autor:
Bradley W. Biggs, Mark O’Neil-Johnson, Parayil Kumaran Ajikumar, Amogh Kambalyal, Chin Giaw Lim, Aditi Das, Courtney M. Starks, William A. Arnold, John Edward Rouck, Marjan De Mey
Publikováno v:
ACS chemical biology. 11(5)
Natural product metabolic engineering potentially offers sustainable and affordable access to numerous valuable molecules. However, challenges in characterizing and assembling complex biosynthetic pathways have prevented more rapid progress in this f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f050f8c7ce4abb4a7d64adf97d7fe4c
https://pubmed.ncbi.nlm.nih.gov/26930136
https://pubmed.ncbi.nlm.nih.gov/26930136
Autor:
Javier L. Baylon, Emad Tajkhorshid, Aditi Das, Yelena V. Grinkova, Jared A. Hammernik, Daryl D. Meling, Daniel R. McDougle, Amogh Kambalyal
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (10):2460-2470
CYP2J2 epoxygenase is an extrahepatic, membrane bound cytochrome P450 (CYP) that is primarily found in the heart and mediates endogenous fatty acid metabolism. CYP2J2 interacts with membranes through an N-terminal anchor and various non-contiguous hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c728f4945af213046c659b6c27c6bb24