Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Amna Asif-Laidin"'
Autor:
Amna Asif-Laidin, Karine Casier, Zoheir Ziriat, Antoine Boivin, Elise Viodé, Valérie Delmarre, Stéphane Ronsseray, Clément Carré, Laure Teysset
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background A fraction of all genomes is composed of transposable elements (TEs) whose mobility needs to be carefully controlled. In gonads, TE activity is repressed by PIWI-interacting RNAs (piRNAs), a class of small RNAs synthesized by hete
Externí odkaz:
https://doaj.org/article/3327625793124bc1af5e9afd6c06390c
Autor:
Phong Quoc Nguyen, Sonia Huecas, Amna Asif-Laidin, Adrián Plaza-Pegueroles, Beatrice Capuzzi, Noé Palmic, Christine Conesa, Joël Acker, Juan Reguera, Pascale Lesage, Carlos Fernández-Tornero
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Cryo-EM structures of Ty1 integrase-Pol III complexes reveal determinants of Ty1 targeting upstream of Pol III-transcribed genes, and a functional impact of the integrase on Pol III activity that may increase the probability of Ty1 integration.
Externí odkaz:
https://doaj.org/article/ae5e1040373b42eb93f7571525af5479
Autor:
Anastasia Barkova, Indranil Adhya, Christine Conesa, Amna Asif-Laidin, Amandine Bonnet, Elise Rabut, Carine Chagneau, Pascale Lesage, Joël Acker
Publikováno v:
Mobile DNA, Vol 13, Iss 1, Pp 1-19 (2022)
Abstract Background Transposable elements are ubiquitous and play a fundamental role in shaping genomes during evolution. Since excessive transposition can be mutagenic, mechanisms exist in the cells to keep these mobile elements under control. Altho
Externí odkaz:
https://doaj.org/article/53111f1a5c5f48a194b3d5c26d9dc0a2
Autor:
Phong Quoc Nguyen, Sonia Huecas, Amna Asif-Laidin, Adrián Plaza-Pegueroles, Noé Palmic, Joël Acker, Juan Reguera, Pascale Lesage, Carlos Fernández-Tornero
SummaryThe yeast Ty1 retrotransposon integrates upstream of genes transcribed by RNA polymerase III (Pol III). Specificity of integration is mediated by an interaction between the Ty1 integrase (IN1) and Pol III, currently uncharacterized at the atom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7497fda6a62427370447da274cd2e646
https://doi.org/10.1101/2022.03.07.483246
https://doi.org/10.1101/2022.03.07.483246
Autor:
Noé Palmic, Joël Acker, Pascale Lesage, Christine Conesa, Rachid Menouni, Amandine Bonnet, Hélène Fayol, Camille Grison, Amna Asif-Laidin, Indranil Adhya
SUMMARYIntegration of transposable elements into the genome is mutagenic. Mechanisms that target integration into relatively safe locations and minimize deleterious consequences for cell fitness have emerged during evolution. In budding yeast, the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a84d2596ca0c3f9c58894f500e0368c6
https://doi.org/10.1101/2019.12.18.879569
https://doi.org/10.1101/2019.12.18.879569
Autor:
Valérie Delmarre, Wolfgang J. Miller, Stéphane Ronsseray, Jeanne Laurentie, Laure Teysset, Amna Asif-Laidin
Publikováno v:
DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes
DNA Research
DNA Research, 2017, 24 (5), pp.459-472. ⟨10.1093/dnares/dsx017⟩
DNA Research, Oxford University Press (OUP), 2017, 24 (5), pp.459-472. ⟨10.1093/dnares/dsx017⟩
DNA Research
DNA Research, 2017, 24 (5), pp.459-472. ⟨10.1093/dnares/dsx017⟩
DNA Research, Oxford University Press (OUP), 2017, 24 (5), pp.459-472. ⟨10.1093/dnares/dsx017⟩
International audience; Two Telomeric Associated Sequences, TAS-R and TAS-L, form the principal subtelomeric repeat families identified in Drosophila melanogaster. They are PIWI-interacting RNA (piRNA) clusters involved in repression of Transposable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80cba34bae9b32c8af655780b9366806
https://doi.org/10.1093/dnares/dsx017
https://doi.org/10.1093/dnares/dsx017
Publikováno v:
METHODS IN ENZYMOLOGY : High-Density Sequencing Applications in Microbial Molecular Genetics
METHODS IN ENZYMOLOGY : High-Density Sequencing Applications in Microbial Molecular Genetics, Elsevier, 2018, ⟨10.1016/bs.mie.2018.08.002⟩
METHODS IN ENZYMOLOGY : High-Density Sequencing Applications in Microbial Molecular Genetics, Elsevier, 2018, ⟨10.1016/bs.mie.2018.08.002⟩
Transposable elements (TEs) are present in virtually all organisms. TE integration into genomes contributes to their structure and evolution, but can also be harmful in some cases. Deciphering where and how TE integration is targeted is fundamental t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d238d17f79aa0ff50ad54fd1fc0f276
https://hal.archives-ouvertes.fr/hal-02416741/document
https://hal.archives-ouvertes.fr/hal-02416741/document
Autor:
Amna Asif-Laidin, Christophe Antoniewski, Valérie Delmarre, Marius van den Beek, Stéphane Ronsseray, Catherine Hermant, Antoine Boivin, Laure Teysset
Publikováno v:
Genetics
Genetics, Genetics Society of America, 2015, 201 (4), pp.1381+. ⟨10.1534/genetics.115.180307⟩
Genetics, 2015, 201 (4), pp.1381+. ⟨10.1534/genetics.115.180307⟩
Genetics, Genetics Society of America, 2015, 201 (4), pp.1381+. ⟨10.1534/genetics.115.180307⟩
Genetics, 2015, 201 (4), pp.1381+. ⟨10.1534/genetics.115.180307⟩
Transposable element activity is repressed in the germline in animals by PIWI-interacting RNAs (piRNAs), a class of small RNAs produced by genomic loci mostly composed of TE sequences. The mechanism of induction of piRNA production by these loci is s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a966bc1d3d3c043b0873fe39a4c3af3d
https://europepmc.org/articles/PMC4676525/
https://europepmc.org/articles/PMC4676525/