Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Amna, Ghith"'
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 9, p 328 (2024)
Background: Lactation is associated with long-term reduced risk of breast cancer. However, there is a transient increased risk of breast cancer in the 5 to 10 years postpartum and this is associated with a high incidence of metastasis and mortality.
Externí odkaz:
https://doaj.org/article/17323047e4b54a62a7753eeb018f210d
Autor:
Amna Ghith, Daniel Z. Doherty, John B. Bruning, Robert A. Russell, James J. De Voss, Stephen G. Bell
Publikováno v:
ACS Infectious Diseases. 8:1606-1617
The oxidation of cholesterol derivatives by the CYP124 and CYP142 enzymes from Mycobacterium marinum
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 231:106317
Publikováno v:
Archives of Biochemistry and Biophysics. 737:109554
Publikováno v:
Bioorganic Chemistry. 83:111-128
Different series of novel thieno [2,3-d]pyrimidine derivative (9a-d,10a-f,l,m and 15a-m) were designed, synthesized and evaluated for their ability to in vitro inhibit VEGFR-2 enzyme. Also, the cytotoxicity of the final compounds was tested against a
Publikováno v:
Journal of Inorganic Biochemistry. 209:111116
The steroid lipid binding cytochrome P450 (CYP) enzymes of Mycobacterium tuberculosis are essential for organism survival through metabolism of cholesterol and its derivatives. The counterparts to these enzymes from Mycobacterium marinum were studied
Publikováno v:
Archiv der Pharmazie. 350(11)
Thienopyrimidines (TP), comprising a thiophene ring fused with pyrimidine, are famous bioisosteres to purines, an essential part of the human metabolome. This scaffold has become an interesting structural element in the development of pharmaceutical
Publikováno v:
Archiv der Pharmazie. 350:1700242
Thienopyrimidines (TP), comprising a thiophene ring fused with pyrimidine, are famous bioisosteres to purines, an essential part of the human metabolome. This scaffold has become an interesting structural element in the development of pharmaceutical