Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Amna, Abderrazak"'
1
Akademický článek
Major areas of interest of artificial intelligence research applied to health care administrative data: a scoping review
Autor: Olga Bukhtiyarova, Amna Abderrazak, Yohann Chiu, Stephanie Sparano, Marc Simard, Caroline Sirois
Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)
Introduction: The ongoing collection of large medical data has created conditions for application of artificial intelligence (AI) in research. This scoping review aimed to identify major areas of interest of AI applied to health care administrative d
Externí odkaz: https://doaj.org/article/412e381a265d49bf91d516974bea8e16
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2
Akademický článek
Alpha2beta1 Integrin (VLA-2) Protects Activated Human Effector T Cells From Methotrexate-Induced Apoptosis
Autor: Amna Abderrazak, Mohammed-Amine El Azreq, Dalila Naci, Paul R. Fortin, Fawzi Aoudjit
Publikováno v: Frontiers in Immunology, Vol 9 (2018)
β1 integrins are critical for T cell migration, survival and costimulation. The integrin α2β1, which is a receptor for collagen, also named VLA-2, is a major costimulatory pathway of effector T cells and has been implicated in arthritis pathogenes
Externí odkaz: https://doaj.org/article/fcda1369c94e4c948977b3b1ae4b1959
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3
Akademický článek
NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases
Autor: Amna Abderrazak, Tatiana Syrovets, Dominique Couchie, Khadija El Hadri, Bertrand Friguet, Thomas Simmet, Mustapha Rouis
Publikováno v: Redox Biology, Vol 4, Iss C, Pp 296-307 (2015)
IL-1β production is critically regulated by cytosolic molecular complexes, termed inflammasomes. Different inflammasome complexes have been described to date. While all inflammasomes recognize certain pathogens, it is the distinctive feature of NLRP
Externí odkaz: https://doaj.org/article/27a8a3be4b564a5bb6566f626d1de3de
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4
The Purinergic Receptor P2X4 Promotes Th17 Activation and the Development of Arthritis
Autor: Chakib Hamoudi, Chenqi Zhao, Amna Abderrazak, Mabrouka Salem, Paul R. Fortin, Jean Sévigny, Fawzi Aoudjit
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 208(5)
Purinergic signaling plays a major role in T cell activation leading to IL-2 production and proliferation. However, it is unclear whether purinergic signaling contributes to the differentiation and activation of effector T cells. In this study, we fo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b197092e5a974e9207dcd63e5a86c06
https://pubmed.ncbi.nlm.nih.gov/35165166
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5
Human Plasma Thioredoxin-80 Increases With Age and in ApoE −/− Mice Induces Inflammation, Angiogenesis, and Atherosclerosis
Autor: Tamas Fulop, Dler Faieeq Darweesh Mahmood, Magda M. Hamza, Fanny Canesi, Amna Abderrazak, Dominique Couchie, Boris L. Vaisman, Mustapha Rouis, Alan T. Remaley, Vimala Diderot, Khadija El Hadri, Aurélie Le Page, Anne Nègre-Salvayre
Publikováno v: Circulation
Circulation, American Heart Association, 2017, 136 (5), pp.464-475. ⟨10.1161/CIRCULATIONAHA.117.027612⟩
Circulation, 2017, 136 (5), pp.464-475. ⟨10.1161/CIRCULATIONAHA.117.027612⟩
Background: Thioredoxin (TRX)-1, a ubiquitous 12-kDa protein, exerts antioxidant and anti-inflammatory effects. In contrast, the truncated form, called TRX80, produced by macrophages induces upregulation of proinflammatory cytokines. TRX80 also promo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21e58df74e21e81435a05c7381fd14a
https://hal.archives-ouvertes.fr/hal-02349881
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6
Truncated thioredoxin (Trx-80) promotes pro-inflammatory macrophages of the M1 phenotype and enhances atherosclerosis
Autor: Mohamed-Naceur Slimane, Fabien Gosselet, Dler Faieeq Darweesh Mahmood, Thomas Simmet, Mustapha Rouis, Oleg Lunov, Dominique Couchie, Khadija El Hadri, Vimala Diderot, Amna Abderrazak, Tatiana Syrovets
Publikováno v: Journal of Cellular Physiology
Journal of Cellular Physiology, 2013, 228 (7), pp.1577-1583. ⟨10.1002/jcp.24319⟩
Journal of Cellular Physiology, Wiley, 2013, 228 (7), pp.1577-1583. ⟨10.1002/jcp.24319⟩
Vascular cells are particularly susceptible to oxidative stress that is believed to play a key role in the pathogenesis of cardiovascular disorders. Thioredoxin-1 (Trx-1) is an oxidative stress-limiting protein with anti-inflammatory and anti-apoptot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b5ea89e5bd4c67bfb6e3ec4c7e0bdf
https://doi.org/10.1002/jcp.24319
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7
Human Plasma Thioredoxin-80 Increases With Age and in ApoE
Autor: Dominique, Couchie, Boris, Vaisman, Amna, Abderrazak, Dler Faieeq Darweesh, Mahmood, Magda M, Hamza, Fanny, Canesi, Vimala, Diderot, Khadija, El Hadri, Anne, Nègre-Salvayre, Aurélie, Le Page, Tamas, Fulop, Alan T, Remaley, Mustapha, Rouis
Publikováno v: Circulation
Thioredoxin (TRX)-1, a ubiquitous 12-kDa protein, exerts antioxidant and anti-inflammatory effects. In contrast, the truncated form, called TRX80, produced by macrophages induces upregulation of proinflammatory cytokines. TRX80 also promotes the diff
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d3ed52e8c8275248efa75628d0fa4f04
https://pubmed.ncbi.nlm.nih.gov/28473446
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8
Inhibition of the Inflammasome NLRP3 by Arglabin Attenuates Inflammation, Protects Pancreatic beta-Cells from Apoptosis, and Prevents Type 2 Diabetes Mellitus Development in ApoE(2)Ki Mice on a Chronic High-Fat Diet
Autor: Mohamed-Naceur Slimane, Dominique Couchie, Berthold Büchele, Thomas Simmet, Mustapha Rouis, Bertrand Blondeau, Amna Abderrazak, Elodie Bosc, Khadija El Hadri
Publikováno v: Journal of Pharmacology and Experimental Therapeutics
Journal of Pharmacology and Experimental Therapeutics, American Society for Pharmacology and Experimental Therapeutics, 2016, 357 (3), pp.487-494. ⟨10.1124/jpet.116.232934⟩
Journal of Pharmacology and Experimental Therapeutics, 2016, 357 (3), pp.487-494. ⟨10.1124/jpet.116.232934⟩
International audience; Intraperitoneal injection of arglabin (2.5 ng/g of body weight, twice daily, 13 weeks) into female human apolipoprotein E-2 gene knock-in (ApoE(2)Ki) mice fed a high-fat Western-type diet (HFD) reduced plasma levels of glucose
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5ddb72d1fc8f650203bfe9a91422b5
https://hal.archives-ouvertes.fr/hal-01544052
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9
Response to Letter Regarding Article, 'Anti-inflammatory and Antiatherogenic Effects of the Inflammasome NLRP3 Inhibitor Arglabin in ApoE2.Ki Mice Fed a High-Fat Diet'
Autor: Tamas Fulop, Thomas Simmet, Rima Elhage, Amna Abderrazak, Mustapha Rouis, Dominique Couchie, Menna El Gaafary, Bertrand Friguet, Khadija El Hadri, Cécile Vindis, Tatiana Syrovets, Monica Rubio Ayala, Dler Faieeq Darweesh Mahmood, Muriel Laffargue, Berthold Büchele, Mohamed-Naceur Slimane, Véronique Mateo
Publikováno v: Circulation
Circulation, American Heart Association, 2015, 132 (21), pp.e250-e251. ⟨10.1161/CIRCULATIONAHA.115.017739⟩
Circulation, 2015, 132 (21), pp.e250-e251. ⟨10.1161/CIRCULATIONAHA.115.017739⟩
In response to the letter of Drs Takahashi and Karasawa, we thought it might be of interest to open the debate about the mechanism by which arglabin, a natural compound isolated from Artemisia glabella , inhibits cholesterol crystal–induced activat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd32c140c736d23bf80e70b9f90954f
https://hal.archives-ouvertes.fr/hal-01544055
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10
Anti-Inflammatory and Antiatherogenic Effects of the NLRP3 Inflammasome Inhibitor Arglabin in ApoE(2).Ki Mice Fed a High-Fat Diet
Autor: Tatiana Syrovets, Mohamed-Naceur Slimane, Dominique Couchie, Monica Rubio Ayala, Rima Elhage, Amna Abderrazak, Tamas Fulop, Muriel Laffargue, Véronique Mateo, Bertrand Friguet, Thomas Simmet, Cécile Vindis, Berthold Büchele, Mustapha Rouis, Dler Faieeq Darweesh Mahmood, Menna El Gaafary, Khadija El Hadri
Publikováno v: Circulation
Circulation, American Heart Association, 2015, 131 (12), pp.1061-1070. ⟨10.1161/CIRCULATIONAHA.114.013730⟩
Circulation, 2015, 131 (12), pp.1061-1070. ⟨10.1161/CIRCULATIONAHA.114.013730⟩
Background— This study was designed to evaluate the effect of arglabin on the NLRP3 inflammasome inhibition and atherosclerotic lesion in ApoE 2 Ki mice fed a high-fat Western-type diet. Methods and Results— Arglabin was purified, and its chemica
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9471c05603fcf16138fe0c84c3949e1b
https://hal.archives-ouvertes.fr/hal-01543968
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