Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ammon Crapo"'
Publikováno v:
Molecular Biology of the Cell
Kinesin-8 motor proteins destabilize microtubules. Their absence during cell division is associated with disorganized mitotic chromosome movements and chromosome loss. Despite recent work studying effects of kinesin 8s on microtubule dynamics, it rem
Autor:
Eileen T. O'Toole, Adam Lamson, Christopher Edelmaier, Loren E. Hough, Ammon Crapo, Oliver Sweezy-Schindler, Zachary R. Gergely, J. Richard McIntosh, Matthew A. Glaser, Robert Blackwell, Meredith D. Betterton
Publikováno v:
Science Advances
A physical model that exhibits de novo bipolar spindle assembly is used to study the mechanisms of spindle bipolarity.
Mitotic spindles use an elegant bipolar architecture to segregate duplicated chromosomes with high fidelity. Bipolar spindles
Mitotic spindles use an elegant bipolar architecture to segregate duplicated chromosomes with high fidelity. Bipolar spindles
Autor:
Ammon Crapo, Christopher Edelmaier, Alireza Doostan, Meredith D. Betterton, Patrick J. Flynn, Matthew A. Glaser, Zachary R. Gergely, Robert Blackwell, J. Richard McIntosh, Oliver Sweezy-Schindler, Salvador Montes
Publikováno v:
Biophysical journal. 112(3)
Microtubule dynamic instability allows search and capture of kinetochores during spindle formation, an important process for accurate chromosome segregation during cell division. Recent work has found that microtubule rotational diffusion about minus
Autor:
Robert Blackwell, Christopher Edelmaier, Oliver Sweezy-Schindler, Adam Lamson, Zachary Gergely, Eileen O'Toole, Ammon Crapo, Loren Hough, Richard McIntosh, Matthew Glaser, Meredith Betterton
Publikováno v:
Biophysical Journal. 112:432a
Publikováno v:
Biophysical Journal. (2):327a
The fission yeast proteins Klp5p and Klp6p are plus-end directed motors of the kinesin-8 family known to promote microtubule depolymerization. During mitosis these motors localize to the mitotic spindle. Although the kinesin 8s are not essential for