Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ammar M. Almaaytah"'
Publikováno v:
Pharmacia, Vol 70, Iss 2, Pp 337-349 (2023)
Epigenetic changes have a major effect in both normal and disease cases of organism. Multiple types of epigenetic changes as acetylation, methylation on either DNA or histone proteins, phosphorylation, or ubiquitination. Epigenetic changes are associ
Externí odkaz:
https://doaj.org/article/aced6f2086294bf8965dbcca1da14cea
Autor:
Mohamed J. Saadh, Samer A. Tanash, Ammar M. Almaaytah, Issam J. Sa'adeh, Saed M. Aldalaen, Khawla D. Al-Hamaideh
Publikováno v:
Veterinary World, Vol 14, Iss 8, Pp 2097-2101 (2021)
Background and Aim: Diagnosis of fascioliasis depends on clinical symptoms and routine laboratory tests. Recently, antibodies and circulating antigens of Fasciola were used for detecting active infections. Therefore, this study aimed to identify Fasc
Externí odkaz:
https://doaj.org/article/f0867e18fc7440529f93d95940776724
Autor:
Mohd Alaraj, Tolgahan Acar, Irena Kosinska, Bahaa Al-Trad, Ammar M. Almaaytah, Mohamed J. Saadh, Mohammed A. Qumani, Shahid M. Syed, Khalil I. Altaif, Hossain Ashfaque
Publikováno v:
Veterinary World, Vol 14, Iss 3, Pp 589-594 (2021)
Background and Aim: Paracetamol (PCM) ingestion is one of the most frequent global causes of toxicity. Salvadora persica L. is a plant that among many other effects exhibits potent antioxidant, anti-inflammatory, antimicrobial, and anticancer effects
Externí odkaz:
https://doaj.org/article/3eee23673239434982a3a7f7433fac7c
Publikováno v:
Veterinary World, Vol 13, Iss 8, Pp 1517-1523 (2020)
Background and Aim: The beta toxin is causing the most severe Clostridium perfringens-related diseases. This work was dedicated to developing a vaccine against beta toxin using C. perfringens type C (NCTC 3180). Materials and Methods: The crude to
Externí odkaz:
https://doaj.org/article/16c3198eaaf545959e920dee6c7856ae
Autor:
Qosay A. Al-Balas, Mousa L. Al-Smadi, Mohammad A. Hassan, Ghazi A. Al Jabal, Ammar M. Almaaytah, Karem H. Alzoubi
Publikováno v:
Molecules, Vol 24, Iss 18, p 3210 (2019)
Glyoxalase-I (Glo-I) enzyme was established to be a valid target for anticancer drug design. It performs the essential detoxification step of harmful byproducts, especially methylglyoxal. A robust computer-aided drug design approach was used to desig
Externí odkaz:
https://doaj.org/article/2d74d921deac41158120fd47edf65daf
Autor:
Nizar M. Mhaidat, Ammar M. Almaaytah, Mohammad A. Hassan, Amjad M. Qandil, Haneen A. Amawi, Qosay A. Al-Balas
Publikováno v:
Pharmaceuticals, Vol 6, Iss 6, Pp 700-715 (2013)
Farnesyltransferase enzyme (FTase) is considered an essential enzyme in the Ras signaling pathway associated with cancer. Thus, designing inhibitors for this enzyme might lead to the discovery of compounds with effective anticancer activity. In an at
Externí odkaz:
https://doaj.org/article/14a0197bf3b74e04bfa6a5c33953df3b
Autor:
Qosay A, Al-Balas, Mohammad A, Hassan, Nizar A, Al-Shar'i, Nizar M, Mhaidat, Ammar M, Almaaytah, Fatima M, Al-Mahasneh, Israa H, Isawi
Publikováno v:
Drug Design, Development and Therapy
Background The glyoxalase system including two thiol-dependent enzymes, glyoxalase I (Glo-I) and glyoxalase II, plays an important role in a ubiquitous metabolic pathway involved in cellular detoxification of cytotoxic 2-oxoaldehydes. Tumor cells hav