Dapsone- and nitroso dapsone-specific activation of T cells from hypersensitive patients expressing the risk allele HLA-B*13:01.

Autor: Zhao Q; MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, The University of Liverpool, Liverpool, UK.; Department of Dermatology, Shandong Provincial Hospital for Skin Disease, Shandong University, Jinan, China.; Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan, China., Alhilali K; MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, The University of Liverpool, Liverpool, UK., Alzahrani A; MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, The University of Liverpool, Liverpool, UK.; Al Baha University, Prince Mohammad Bin Saud, Al Bahah, Saudi Arabia.; Pharmacology Department, College of Clinical Pharmacy, AlBaha University, Al Baha, Saudi Arabia., Almutairi M; MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, The University of Liverpool, Liverpool, UK., Amjad J; MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, The University of Liverpool, Liverpool, UK., Liu H; Department of Dermatology, Shandong Provincial Hospital for Skin Disease, Shandong University, Jinan, China.; Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan, China., Sun Y; Department of Dermatology, Shandong Provincial Hospital for Skin Disease, Shandong University, Jinan, China.; Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan, China., Sun L; Department of Dermatology, Shandong Provincial Hospital for Skin Disease, Shandong University, Jinan, China.; Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan, China., Zhang H; Department of Dermatology, Shandong Provincial Hospital for Skin Disease, Shandong University, Jinan, China.; Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan, China., Meng X; MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, The University of Liverpool, Liverpool, UK., Gibson A; MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, The University of Liverpool, Liverpool, UK., Ogese MO; MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, The University of Liverpool, Liverpool, UK.; Pathological Sciences, drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Cambridge, UK., Kevin Park B; MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, The University of Liverpool, Liverpool, UK., Liu J; Human Genetics, Genome Institute of Singapore, A*STAR, Singapore, Singapore., Ostrov DA; Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, Florida., Zhang F; Department of Dermatology, Shandong Provincial Hospital for Skin Disease, Shandong University, Jinan, China.; Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan, China., Naisbitt DJ; MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, The University of Liverpool, Liverpool, UK.

Publikováno v: Allergy [Allergy] 2019 Aug; Vol. 74 (8), pp. 1533-1548. Date of Electronic Publication: 2019 Apr 15.