Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Amitesh Anand"'
Autor:
Nikita Goel, Stuti Srivastav, Arjun Patel, Akshay Shirsath, Tushar Ranjan Panda, Malay Patra, Adam M. Feist, Amitesh Anand
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT The bacterial lifestyle is plastic, requiring transcriptional, translational, and metabolic tailoring for survival. These dynamic cellular processes are energy intensive; therefore, flexible energetics is requisite for adaptive plasticity. A
Externí odkaz:
https://doaj.org/article/20ac74f2c8a543d1b456e7d91a8877cf
Autor:
Kevin Rychel, Justin Tan, Arjun Patel, Cameron Lamoureux, Ying Hefner, Richard Szubin, Josefin Johnsen, Elsayed Tharwat Tolba Mohamed, Patrick V. Phaneuf, Amitesh Anand, Connor A. Olson, Joon Ho Park, Anand V. Sastry, Laurence Yang, Adam M. Feist, Bernhard O. Palsson
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113105- (2023)
Summary: Relationships between the genome, transcriptome, and metabolome underlie all evolved phenotypes. However, it has proved difficult to elucidate these relationships because of the high number of variables measured. A recently developed data an
Externí odkaz:
https://doaj.org/article/3fa5f4f1b24a41dda13d125aac6d22b6
Autor:
Amitesh Anand, Arjun Patel, Ke Chen, Connor A. Olson, Patrick V. Phaneuf, Cameron Lamoureux, Ying Hefner, Richard Szubin, Adam M. Feist, Bernhard O. Palsson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
The bacterial respiratory electron transport system (ETS) is branched to allow condition-specific modulation of energy metabolism. Here the authors examine the systems level properties of aerobic electron transport system using adaptive laboratory ev
Externí odkaz:
https://doaj.org/article/2a048520a218438793dbdfbe86ca7d20
Autor:
Henrique Machado, Yara Seif, George Sakoulas, Connor A. Olson, Ying Hefner, Amitesh Anand, Ying Z. Jones, Richard Szubin, Bernhard O. Palsson, Victor Nizet, Adam M. Feist
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Henrique Machado et al. describe mutational mechanisms associated with MRSA vancomycin resistance in Staphylococcus aureus using adaptive laboratory evolution experiments focused on tolerance. Their results reveal environment-dependent mutational str
Externí odkaz:
https://doaj.org/article/c389d118dc5044379b2f7e0d3dda2b45
Autor:
Anand V. Sastry, Nicholas Dillon, Amitesh Anand, Saugat Poudel, Ying Hefner, Sibei Xu, Richard Szubin, Adam M. Feist, Victor Nizet, Bernhard Palsson
Publikováno v:
mSphere, Vol 6, Iss 4 (2021)
Antibiotic resistance is an imminent threat to global health. Patient treatment regimens are often selected based on results from standardized antibiotic susceptibility testing (AST) in the clinical microbiology lab, but these in vitro
Externí odkaz:
https://doaj.org/article/220d392333e94177905596f8b6ded2e1
Autor:
Amitesh Anand, Connor A. Olson, Anand V. Sastry, Arjun Patel, Richard Szubin, Laurence Yang, Adam M. Feist, Bernhard O. Palsson
Publikováno v:
Cell Reports, Vol 35, Iss 1, Pp 108961- (2021)
Summary: Pyruvate dehydrogenase complex (PDC) functions as the main determinant of the respiro-fermentative balance because it converts pyruvate to acetyl-coenzyme A (CoA), which then enters the TCA (tricarboxylic acid cycle). PDC is repressed by the
Externí odkaz:
https://doaj.org/article/bef38c16a54044e29340bad0620d687d
Autor:
Ke Chen, Amitesh Anand, Connor Olson, Troy E Sandberg, Ye Gao, Nathan Mih, Bernhard O Palsson
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 1, p e1008596 (2021)
The fitness landscape is a concept commonly used to describe evolution towards optimal phenotypes. It can be reduced to mechanistic detail using genome-scale models (GEMs) from systems biology. We use recently developed GEMs of Metabolism and protein
Externí odkaz:
https://doaj.org/article/9067672e738c4062a54ed4a386837593
Autor:
Erol S. Kavvas, Edward Catoiu, Nathan Mih, James T. Yurkovich, Yara Seif, Nicholas Dillon, David Heckmann, Amitesh Anand, Laurence Yang, Victor Nizet, Jonathan M. Monk, Bernhard O. Palsson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Mycobacterium tuberculosis exhibits complex evolution of antimicrobial resistance (AMR). Here, the authors perform machine learning and structural analysis to identify signatures of AMR evolution to 13 antibiotics.
Externí odkaz:
https://doaj.org/article/43c5a44a956f4bc3a0b1035a0afc669c
Autor:
Samal, Chirag, Jakimowicz, Kasia, Dasgupta, Krishnendu, Vashishtha, Aniket, O., Francisco, Natarajan, Arunakiry, Nazir, Haris, Varma, Alluri Siddhartha, Dahake, Tejal, Pandey, Amitesh Anand, Singh, Ishaan, Kim, John Sangyeob, Gill, Mehrab Singh, Srivastava, Saurish, Mukhopadhyay, Orna, Patwa, Parth, Mirza, Qamil, Irshad, Sualeha, Shankar, Sheshank, Iyer, Rohan, Sukumaran, Rohan, Mehra, Ashley, Sharma, Anshuman, Singh, Abhishek, Arseni, Maurizio, T V, Sethuraman, Agrawal, Saras, Sharma, Vivek, Raskar, Ramesh
The Coronavirus 2019 (Covid-19) pandemic caused by the SARS-CoV-2 virus represents an unprecedented crisis for our planet. It is a bane of the \"uber connected world that we live in that this virus has affected almost all countries and caused mortali
Externí odkaz:
http://arxiv.org/abs/2107.14139
Autor:
Kevin Rychel, Justin Tan, Arjun Patel, Cameron Lamoureux, Ying Hefner, Richard Szubin, Josefin Johnsen, Elsayed Tharwat Tolba Mohamed, Patrick V. Phaneuf, Amitesh Anand, Connor A. Olson, Joon Ho Park, Anand V. Sastry, Laurence Yang, Adam M. Feist, Bernhard O. Palsson
SummaryRelationships between the genome, transcriptome, and metabolome underlie all evolved phenotypes. However, it has proved difficult to elucidate these relationships because of the high number of variables measured. A recently developed data anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5606d7d30bdd12286b00ca1584020b1b
https://doi.org/10.1101/2022.12.20.521246
https://doi.org/10.1101/2022.12.20.521246