Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Amitabha Majumdar"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Huntington’s disease (HD) is a rare neurodegenerative disease caused due to aggregation of Huntingtin (HTT) protein. This study involves the cloning of 40 DnaJ chaperones from Drosophila, and overexpressing them in yeasts and fly models of
Externí odkaz:
https://doaj.org/article/f23e0c0101c14016a2d49203166a839b
Autor:
Meghal Desai, Hemant, Ankita Deo, Jagyanseni Naik, Prathamesh Dhamale, Avinash Kshirsagar, Tania Bose, Amitabha Majumdar
Publikováno v:
PLoS Biology, Vol 22, Iss 4, p e3002585 (2024)
Orb2 the Drosophila homolog of cytoplasmic polyadenylation element binding (CPEB) protein forms prion-like oligomers. These oligomers consist of Orb2A and Orb2B isoforms and their formation is dependent on the oligomerization of the Orb2A isoform. Dr
Externí odkaz:
https://doaj.org/article/0d3b5f18fd5f45b5a9fd5ceaab945a19
Autor:
Tanay Bhatt, Binita Dam, Sneha Uday Khedkar, Sahil Lall, Subhashini Pandey, Sunny Kataria, Johan Ajnabi, Shah-E-Jahan Gulzar, Paul M. Dias, Morris Waskar, Janhavi Raut, Varadharajan Sundaramurthy, Praveen Kumar Vemula, Naresh Ghatlia, Amitabha Majumdar, Colin Jamora
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The continual emergence of SARS-CoV-2 variants threatens to compromise the effectiveness of worldwide vaccination programs, and highlights the need for complementary strategies for a sustainable containment plan. An effective approach is to mobilize
Externí odkaz:
https://doaj.org/article/358aaf12668044f99fbfcc4ce5e175ee
Autor:
Morris Waskar, Xuelan Gu, Tingyan Mi, Meenakshi Swaminathan, Carol Vincent, Rimpa Ghosh, Chandraprabha Doraiswamy, Amitabha Majumdar
Publikováno v:
Antimicrobial Stewardship & Healthcare Epidemiology, Vol 3, Pp s16-s17 (2023)
Objectives: We evaluated the role of 12-hydroxystearic acid (12HSA) in upregulating skin antimicrobial peptides (AMPs) in in vitro and ex vivo assays, and 12HSA provides long-lasting germ protection in vivo through a handwash formulation. Methods: In
Externí odkaz:
https://doaj.org/article/a0d94381212943f19ada03723b0ea2ee
Autor:
Edries Yousaf Hajam, Patricia Panikulam, Chung-Ching Chu, Haarshadri Jayaprakash, Amitabha Majumdar, Colin Jamora
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
As the interface between the body and the environment, the skin functions as the physical barrier against external pathogens and toxic agents. In addition, the skin is an immunologically active organ with a plethora of resident adaptive and innate im
Externí odkaz:
https://doaj.org/article/14fa586013ff47f1b3f34dfe456cb7b9
Autor:
Michaela Zorn-Kruppa, Sabine Vidal-y-Sy, Pia Houdek, Ewa Wladykowski, Stephan Grzybowski, Robert Gruber, Christian Gorzelanny, Jason Harcup, Stefan W. Schneider, Amitabha Majumdar, Johanna M. Brandner
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Abstract Barrier function of hair follicles (HFs) is of great interest because they might be an entry port for allergens/pathogens, but could on the other hand be used for drug delivery or vaccination. Therefore we investigated tight junction (TJ) ba
Externí odkaz:
https://doaj.org/article/bc5fbde3bcd7440382fb6bdc70936aba
Autor:
Tanay Bhatt, Aishwarya Bhosale, Bhavya Bajantri, Mruthyunjaya Swamy Mathapathi, Abrar Rizvi, Giorgio Scita, Amitabha Majumdar, Colin Jamora
Publikováno v:
Cell Reports, Vol 29, Iss 9, Pp 2546-2555.e4 (2019)
Summary: Antimicrobial peptides (AMPs) are the body’s natural innate immune defense against a spectrum of pathogens and can also modulate cell proliferation, chemotaxis, angiogenesis, wound healing, and immune cell activity. Harnessing these divers
Externí odkaz:
https://doaj.org/article/cee25ff0a57f4071bea6cdb17e195343
Autor:
Rubén Hervás, Liying Li, Amitabha Majumdar, María Del Carmen Fernández-Ramírez, Jay R Unruh, Brian D Slaughter, Albert Galera-Prat, Elena Santana, Mari Suzuki, Yoshitaka Nagai, Marta Bruix, Sergio Casas-Tintó, Margarita Menéndez, Douglas V Laurents, Kausik Si, Mariano Carrión-Vázquez
Publikováno v:
PLoS Biology, Vol 14, Iss 1, p e1002361 (2016)
Amyloids are ordered protein aggregates that are typically associated with neurodegenerative diseases and cognitive impairment. By contrast, the amyloid-like state of the neuronal RNA binding protein Orb2 in Drosophila was recently implicated in memo
Externí odkaz:
https://doaj.org/article/77f95cb5f9284cf6befdeef4b438bc58
Autor:
Neha Salgaonkar, Vinitha Kadamkode, Srikala Kumaran, Prathyusha Mallemala, Ernest Christy, Shanthi Appavoo, Amitabha Majumdar, Rupak Mitra, Anindya Dasgupta
Publikováno v:
Experimental Dermatology. 31:1364-1372
Commensal bacteria play a major role in multiple skin functions by providing the first layer of defense against pathogens and maintaining the skin barrier. Staphylococcus epidermidis is one of the most common skin commensals. In this study, we showed