Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Amita M Paranjape"'
Autor:
Amita M Paranjape, Sagar S Desai, Mayilaadumveettil Nishana, Urbi Roy, Namrata M Nilavar, Amrita Mondal, Rupa Kumari, Gudapureddy Radha, Vijeth Kumar Katapadi, Bibha Choudhary, Sathees C Raghavan
Publikováno v:
PLoS Genetics, Vol 18, Iss 10, p e1010421 (2022)
Chromosomal translocations are considered as one of the major causes of lymphoid cancers. RAG complex, which is responsible for V(D)J recombination, can also cleave non-B DNA structures and cryptic RSSs in the genome leading to chromosomal translocat
Externí odkaz:
https://doaj.org/article/54f57c96c51f4ad5b0b272d0cb05032a
Autor:
Bibha Choudhary, Rupa Kumari, Amita M Paranjape, Raghunandan Mahadeva, Sathees C. Raghavan, Namrata M Nilavar, Mayilaadumveettil Nishana
Publikováno v:
Biochemical Journal. 477:3567-3582
Recombination activating genes (RAGs), consisting of RAG1 and RAG2 have ability to perform spatially and temporally regulated DNA recombination in a sequence specific manner. Besides, RAGs also cleave at non-B DNA structures and are thought to contri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec02df052b27d1c09c5583e4e09407c5
https://doi.org/10.1042/bcj20200361
https://doi.org/10.1042/bcj20200361
Publikováno v:
Cell Death Discovery, Vol 6, Iss 1, Pp 1-8 (2020)
Cell Death Discovery
Cell Death Discovery
HIV is a retrovirus that infects CD4+ T lymphocytes in human beings and causes immunodeficiency. In the recent years, various therapies have been developed against HIV, including targeting the HIV specific protein, integrase, responsible for integrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8509549cce1bf6943215f3c7b2cc22
http://link.springer.com/article/10.1038/s41420-020-0281-4
http://link.springer.com/article/10.1038/s41420-020-0281-4
Publikováno v:
DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes
Accumulating evidence suggests that human genome can fold into non-B DNA structures, when appropriate sequence and favourable conditions are present. Among these, G-quadruplexes (G4-DNA) are associated with gene regulation, chromosome fragility and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71079b13494faa0a3b902899c885c313
https://doi.org/10.1093/dnares/dsaa024
https://doi.org/10.1093/dnares/dsaa024
Autor:
Urbi Roy, Mridula Nambiar, Annemarie van Nieuwenhuijze, Mrinal Srivastava, Pushpinder Singh Bawa, Adrian Liston, Bibha Choudhary, Sathees C. Raghavan, Sagar S. Desai, Amita M Paranjape, Rupa Kumari, Gudapureddy Radha, Namrata M Nilavar, Kithiganahalli Narayanaswamy Balaji
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109390-(2021)
Recombination activating genes (RAGs), consisting of RAG1 and RAG2, are stringently regulated lymphoid-specific genes, which initiate V(D)J recombination in developing lymphocytes. We report the regulation of RAG1 through a microRNA (miRNA), miR-29c,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08078d665743ec6f0ea3f1aa9274ab56
https://doi.org/10.1016/j.celrep.2021.109390
https://doi.org/10.1016/j.celrep.2021.109390