Zobrazeno 1 - 10
of 77 980
pro vyhledávání: '"Amit Roy '
Autor:
Samira Merali, David H. Salinger, Maria Palmisano, Amy J. Sehnert, Neelima Thanneer, Hyunmoon Back, Julie D. Seroogy, Daniel D. Gretler, Amit Roy, Vidya Perera
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 9, Pp 1448-1461 (2024)
Abstract Mavacamten is the first cardiac myosin inhibitor approved by the US Food and Drug Administration for the treatment of adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM). The phase III EXPLORER‐HCM (NCT03470545) study use
Externí odkaz:
https://doaj.org/article/2d97afb3b2c44e46bccc7c6593bb0036
Autor:
Peter Chang, Vidya Perera, David H. Salinger, Samira Merali, Neelima Thanneer, Hyunmoon Back, Julie D. Seroogy, Daniel D. Gretler, Amy J. Sehnert, Maria Palmisano, Amit Roy
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 9, Pp 1462-1475 (2024)
Abstract Mavacamten is a selective, allosteric, reversible cardiac myosin inhibitor that has been developed for the treatment of adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM). A population pharmacokinetic (PopPK) model was dev
Externí odkaz:
https://doaj.org/article/eaceb752f6ca46f980e5f1d94592e26c
Publikováno v:
Frontiers in Forests and Global Change, Vol 7 (2024)
Forests are potential habitats for immense terrestrial ecosystems and aquatic biodiversity, performing an essential role in ecological preservation and regulation of climate. The anthropogenic pressures on the forests lead to forest loss, fragmentati
Externí odkaz:
https://doaj.org/article/6315401db47c4ca39c0a8530070f77a8
Autor:
Vivek Vikram Singh, Aisha Naseer, Gothandapani Sellamuthu, Kanakachari Mogilicherla, Roman Gebauer, Amit Roy, Rastislav Jakuš
Publikováno v:
Frontiers in Forests and Global Change, Vol 7 (2024)
Accurate gene expression analysis in Norway spruce (Picea abies) under diverse stress conditions requires the identification of stable reference genes for normalization. Notably, the literature lacks reports on suitable reference genes in Norway spru
Externí odkaz:
https://doaj.org/article/046fe3d75d2d47b9b64953b6f10736b9
Autor:
Samanta, Parthasarathi a, Kundu, Surajit a, Gupta, Abhisek b, Rana, Masud c, Mondal, Nitesh a, ⁎, Chowdhury, Amit Roy b
Publikováno v:
In Results in Surfaces and Interfaces January 2025 18
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
BackgroundClimate change has recently boosted the severity and frequency of pine bark beetle attacks. The bacterial community associated with these beetles acts as “hidden players,” enhancing their ability to infest and thrive on defense-rich pin
Externí odkaz:
https://doaj.org/article/cb25766f877e4ac19af4cacfe0351fc5
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
Anthropogenic activities and subsequent global climate change instigate drastic crop productivity and yield changes. These changes comprise a rise in the number and severity of plant stress factors, which can arise simultaneously or sequentially. Whe
Externí odkaz:
https://doaj.org/article/a1aef8c74aeb46889183a83ad7de0633
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 3, Pp 476-493 (2024)
Abstract Body size has historically been considered the primary source of difference in the pharmacokinetics (PKs) of monoclonal antibodies (mAbs) between children aged greater than or equal to 2 years and adults. The contribution of age‐associated
Externí odkaz:
https://doaj.org/article/0d040e2f25cd49b382cd455e1f251094
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 1, Pp 168-179 (2024)
Abstract An exposure–response (E–R) safety analysis was conducted across adult and pediatric (
Externí odkaz:
https://doaj.org/article/0ca9ac2efb12446eaaede1a000f49f26