Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Amit R, Indap"'
Autor:
Chip Stewart, Deniz Kural, Michael P Strömberg, Jerilyn A Walker, Miriam K Konkel, Adrian M Stütz, Alexander E Urban, Fabian Grubert, Hugo Y K Lam, Wan-Ping Lee, Michele Busby, Amit R Indap, Erik Garrison, Chad Huff, Jinchuan Xing, Michael P Snyder, Lynn B Jorde, Mark A Batzer, Jan O Korbel, Gabor T Marth, Genomes Project
Publikováno v:
PLoS Genetics, Vol 7, Iss 8, p e1002236 (2011)
As a consequence of the accumulation of insertion events over evolutionary time, mobile elements now comprise nearly half of the human genome. The Alu, L1, and SVA mobile element families are still duplicating, generating variation between individual
Externí odkaz:
https://doaj.org/article/bb06859b1fcd42df8b29c66de975a2c7
Autor:
Adam R Boyko, Scott H Williamson, Amit R Indap, Jeremiah D Degenhardt, Ryan D Hernandez, Kirk E Lohmueller, Mark D Adams, Steffen Schmidt, John J Sninsky, Shamil R Sunyaev, Thomas J White, Rasmus Nielsen, Andrew G Clark, Carlos D Bustamante
Publikováno v:
PLoS Genetics, Vol 4, Iss 5, p e1000083 (2008)
Quantifying the distribution of fitness effects among newly arising mutations in the human genome is key to resolving important debates in medical and evolutionary genetics. Here, we present a method for inferring this distribution using Single Nucle
Externí odkaz:
https://doaj.org/article/7d2e6d340ec24e4a8b1cfd2d5ef74e32
Autor:
Chip Stewart, Deniz Kural, Michael P Strömberg, Jerilyn A Walker, Miriam K Konkel, Adrian M Stütz, Alexander E Urban, Fabian Grubert, Hugo Y K Lam, Wan-Ping Lee, Michele Busby, Amit R Indap, Erik Garrison, Chad Huff, Jinchuan Xing, Michael P Snyder, Lynn B Jorde, Mark A Batzer, Jan O Korbel, Gabor T Marth, 1000 Genomes Project
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 7, Iss 8, p e1002236 (2011)
PLoS Genetics, Vol 7, Iss 8, p e1002236 (2011)
As a consequence of the accumulation of insertion events over evolutionary time, mobile elements now comprise nearly half of the human genome. The Alu, L1, and SVA mobile element families are still duplicating, generating variation between individual
Autor:
Gabor T, Marth, Fuli, Yu, Amit R, Indap, Kiran, Garimella, Simon, Gravel, Wen Fung, Leong, Chris, Tyler-Smith, Matthew, Bainbridge, Tom, Blackwell, Xiangqun, Zheng-Bradley, Yuan, Chen, Danny, Challis, Laura, Clarke, Edward V, Ball, Kristian, Cibulskis, David N, Cooper, Bob, Fulton, Chris, Hartl, Dan, Koboldt, Donna, Muzny, Richard, Smith, Carrie, Sougnez, Chip, Stewart, Alistair, Ward, Jin, Yu, Yali, Xue, David, Altshuler, Carlos D, Bustamante, Andrew G, Clark, Mark, Daly, Mark, DePristo, Paul, Flicek, Stacey, Gabriel, Elaine, Mardis, Aarno, Palotie, Richard, Gibbs, Reed A, Cartwright
Publikováno v:
Genome Biology
Background Rare coding variants constitute an important class of human genetic variation, but are underrepresented in current databases that are based on small population samples. Recent studies show that variants altering amino acid sequence and pro