Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Amit Kumar Halder"'
Autor:
Ismail Mondal, Amit Kumar Halder, Nirupam Pattanayak, Sudip Kumar Mandal, Maria Natalia D. S. Cordeiro
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 263 (2024)
Recent research has uncovered a promising approach to addressing the growing global health concern of obesity and related disorders. The inhibition of inositol hexakisphosphate kinase 1 (IP6K1) has emerged as a potential therapeutic strategy. This st
Externí odkaz:
https://doaj.org/article/cf3427b782b64a4fa1fa3e68fcbe0b38
Autor:
Shuvam Sar, Soumya Mitra, Parthasarathi Panda, Subhash C. Mandal, Nilanjan Ghosh, Amit Kumar Halder, Maria Natalia D. S. Cordeiro
Publikováno v:
Molecules, Vol 28, Iss 17, p 6379 (2023)
Human soluble epoxide hydrolase (sEH), a dual-functioning homodimeric enzyme with hydrolase and phosphatase activities, is known for its pivotal role in the hydrolysis of epoxyeicosatrienoic acids. Inhibitors targeting sEH have shown promising potent
Externí odkaz:
https://doaj.org/article/6fdc234186bb460092e9e2f7aaddae48
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
RNA-dependent RNA polymerase (RdRp) is a potential therapeutic target for the discovery of novel antiviral agents for the treatment of life-threatening infections caused by newly emerged strains of the influenza virus. Being one of the most conserved
Externí odkaz:
https://doaj.org/article/8ebb285f153049468fa907519386a132
Autor:
Shivani Gupta, Yadu Nandan Dey, Pushpendra Kannojia, Amit Kumar Halder, Deepti Sharma, Manish M. Wanjari, Shridhar Chougule, Sharad Pawar, Atul Kaushik, Sudesh N. Gaidhani, Shailendra Gurav
Publikováno v:
Phytomedicine Plus, Vol 2, Iss 3, Pp 100281- (2022)
ABSTRACT: Background: Trayodashang guggulu (TG) is a compound Ayurvedic formulation used in Indian traditional system of medicine for the treatment of various inflammatory conditions like arthritis and associated pain.Purpose:To study the analgesic a
Externí odkaz:
https://doaj.org/article/badc255b2dd84d699bbb8752b1efd21d
Autor:
Siddhartha Das Pramanik, Amit Kumar Halder, Ushmita Mukherjee, Dharmendra Kumar, Yadu Nandan Dey, Mogana R
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Histone deacetylases (HDACs) are enzymes that play a role in chromatin remodeling and epigenetics. They belong to a specific category of enzymes that eliminate the acetyl part of the histones’ -N-acetyl lysine, causing the histones to be wrapped co
Externí odkaz:
https://doaj.org/article/7dc6748efdb74530ab50380125a34c94
Publikováno v:
Journal of Cheminformatics, Vol 13, Iss 1, Pp 1-18 (2021)
Abstract Quantitative structure activity relationships (QSAR) modelling is a well-known computational tool, often used in a wide variety of applications. Yet one of the major drawbacks of conventional QSAR modelling is that models are set up based on
Externí odkaz:
https://doaj.org/article/2136dd185ea0417095c4d26545148378
Autor:
Amit Kumar Halder, Reza Haghbakhsh, Iuliia V. Voroshylova, Ana Rita C. Duarte, Maria Natalia D. S. Cordeiro
Publikováno v:
Molecules, Vol 27, Iss 15, p 4896 (2022)
Deep eutectic solvents (DES) are an important class of green solvents that have been developed as an alternative to toxic solvents. However, the large-scale industrial application of DESs requires fine-tuning their physicochemical properties. Among o
Externí odkaz:
https://doaj.org/article/d60809444ed94ea3bc9273df45e1a9bf
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4937 (2022)
Conventional in silico modeling is often viewed as ‘one-target’ or ‘single-task’ computer-aided modeling since it mainly relies on forecasting an endpoint of interest from similar input data. Multitasking or multitarget in silico modeling, in
Externí odkaz:
https://doaj.org/article/5f2daffb772f4a6a8667784ba94a71f1
Publikováno v:
Biomolecules, Vol 11, Iss 11, p 1670 (2021)
The inhibitors of two isoforms of mitogen-activated protein kinase-interacting kinases (i.e., MNK-1 and MNK-2) are implicated in the treatment of a number of diseases including cancer. This work reports, for the first time, a multi-target (or multi-t
Externí odkaz:
https://doaj.org/article/4f3b2261f80d47d98c9b3ee756e03750
Autor:
Amit Kumar Halder, Reza Haghbakhsh, Iuliia V. Voroshylova, Ana Rita C. Duarte, M. Natalia D. S. Cordeiro
Publikováno v:
Molecules, Vol 26, Iss 19, p 5779 (2021)
Deep eutectic solvents (DES) are often regarded as greener sustainable alternative solvents and are currently employed in many industrial applications on a large scale. Bearing in mind the industrial importance of DES—and because the vast majority
Externí odkaz:
https://doaj.org/article/bfe20a4cf8f84f87952bb02f3b833f34