Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Amit Koul"'
Publikováno v:
AIMS Mathematics, Vol 6, Iss 6, Pp 5924-5941 (2021)
The activation of 2'-5'-oligoadenylate synthetase (OAS) enzymes by direct interaction with viral double-stranded RNA (dsRNA) is a key part of the innate immune response to viral infection. A downstream effect of the OAS-dsRNA interaction is to degrad
Externí odkaz:
https://doaj.org/article/5f3765fce04c4fca89c3112669a1e913
Publikováno v:
Brazilian Journal of Forensic Sciences, Medical Law and Bioethics, Vol 10, Iss 4 (2021)
Letters, figures or words are sometimes fraudulently added to a contract or other legal documents after it has been signed or produced. This can drastically change the intent of the document. It is more difficult to detect additions that are skillful
Externí odkaz:
https://doaj.org/article/dc00af05fe1b447bb8623de268bb2ea0
Publikováno v:
Molecular Cancer, Vol 16, Iss 1, Pp 1-15 (2017)
Abstract Background BC200 is a long non-coding RNA expressed at high levels in the brain and elevated in a variety of tumour types. BC200 has a hypothesized role in translational regulation; however, to date the functional role of BC200 in both norma
Externí odkaz:
https://doaj.org/article/7a7cbcd039994e14ab8c40714a9daae5
Publikováno v:
AIMS Mathematics, Vol 6, Iss 6, Pp 5924-5941 (2021)
The activation of 2'-5'-oligoadenylate synthetase (OAS) enzymes by direct interaction with viral double-stranded RNA (dsRNA) is a key part of the innate immune response to viral infection. A downstream effect of the OAS-dsRNA interaction is to degrad
Publikováno v:
Biochemistry and Cell Biology. 98:70-82
Human 2′–5′ oligoadenylate synthetases (OAS) are a family of interferon-inducible proteins that, upon activation by double-stranded RNA, polymerize ATP into 2′–5′ linked oligoadenylates. In this study, we probed the RNA cofactor specifici
Autor:
Jörg Stetefeld, Trushar R. Patel, Sean A. McKenna, Markus Meier, Natalie Krahn, Evan P. Booy, Darren L. Gemmill, Amit Koul, Nikhat Lubna
Publikováno v:
Biophysical Journal
Oligoadenylate synthetases (OASs) are a family of interferon-inducible enzymes that require double-stranded RNA (dsRNA) as a cofactor. Upon binding dsRNA, OAS undergoes a conformational change and is activated to polymerize ATP into 2′-5′-oligoad
Publikováno v:
Methods.
The diverse functional cellular roles played by ribonucleic acids (RNA) have emphasized the need to develop rapid and accurate methodologies to elucidate the relationship between the structure and function of RNA. Structural biology tools such as X-r
Autor:
Trushar R. Patel, Edis Dzananovic, Amit Koul, Sean A. McKenna, Kevin McEleney, Janusz M. Bujnicki, Grzegorz Chojnowski, Soumya Deo
Publikováno v:
Journal of structural biology. 190(2)
2′ 5′-Oligoadenylate synthetases (OAS) are interferon-stimulated proteins that act in the innate immune response to viral infection. Upon binding viral double-stranded RNA, OAS enzymes produce 2′-5′-linked oligoadenylates that stimulate RNase