Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Amit Ketkar"'
Autor:
Amit Ketkar, Reham S. Sewilam, Mason J. McCrury, Jaycelyn S. Hall, Ashtyn Bell, Bethany C. Paxton, Shreyam Tripathi, Julie E.C. Gunderson, Robert L. Eoff
Publikováno v:
RSC Chemical Biology.
The G-quadruplex (G4) selective properties of the Rev1 DNA polymerase differ across species.
Autor:
Philip J. Kingsley, Carmelo J. Rizzo, Plamen P. Christov, Kwangho Kim, Anoop Vemulapalli, Robert L. Eoff, Carol A. Rouzer, Amit Ketkar, Lawrence J. Marnett, Gary A. Sulikowski, Robyn Richie-Jannetta
Publikováno v:
Chemical Research in Toxicology. 34:2567-2578
The lipid peroxidation product malondialdehyde and the DNA peroxidation product base-propenal react with dG to generate the exocyclic adduct, M1dG. This mutagenic lesion has been found in human genomic and mitochondrial DNA. M1dG in genomic DNA is en
Autor:
Justin W.C. Leung, Jessica H. Hartman, Makayla Berry, Robert L. Eoff, Lane Smith, Alyssa Richey, Julie Gunderson, Leena Maddukuri, Callie Johnson, Megan R. Reed, Amit Ketkar
Publikováno v:
Nucleic Acids Research
We previously reported that human Rev1 (hRev1) bound to a parallel-stranded G-quadruplex (G4) from the c-MYC promoter with high affinity. We have extended those results to include other G4 motifs, finding that hRev1 exhibited stronger affinity for pa
Autor:
Plamen P, Christov, Robyn, Richie-Jannetta, Philip J, Kingsley, Anoop, Vemulapalli, Kwangho, Kim, Gary A, Sulikowski, Carmelo J, Rizzo, Amit, Ketkar, Robert L, Eoff, Carol A, Rouzer, Lawrence J, Marnett
Publikováno v:
Chemical research in toxicology. 34(12)
The lipid peroxidation product malondialdehyde and the DNA peroxidation product base-propenal react with dG to generate the exocyclic adduct, M
Autor:
Xian Zhang, Weina Zhang, Amit Ketkar, Chuan Xu, Zhong-Zhu Chen, Emily Lin, Guoxiang Jin, Hong-yu Li, Che-Chia Hsu, Zhen Cai, Zhi-Gang Xu, Haiwei Gu, Tingjin Chen, Bo-Syong Pan, Hui Kuan Lin, Yan Jin, Robert L. Eoff, Xiangshang Xu, Guihua Wang, Rajesh Kumar Manne, Wei Yan, Jing-Wei Shao
Publikováno v:
Mol Cell
Mitochondrial dynamics regulated by mitochondrial fusion and fission maintain mitochondrial functions, whose alterations underline various human diseases. Here, we show that inositol is a critical metabolite directly restricting AMPK-dependent mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855ebc5de6492ed6dca554257701c386
https://europepmc.org/articles/PMC8462099/
https://europepmc.org/articles/PMC8462099/
Autor:
Robert L. Eoff, Justin W.C. Leung, Maroof K. Zafar, Amit Ketkar, Analiz Rodriguez, Megan R. Reed, Leena Maddukuri
Publikováno v:
The FASEB Journal. 35
Publikováno v:
The FASEB Journal. 35
Autor:
Jessica Hartman, Amit Ketkar, Alyssa Richey, Megan Reed, Lane Smith, Julie Gunderson, Leena Maddukuri, Robert L. Eoff, Makayla Berry, Justin W.C. Leung, Callie Johnson
Publikováno v:
The FASEB Journal. 35
Autor:
Narsimha Reddy Penthala, Amit Ketkar, Peter A. Crooks, Maroof K. Zafar, Leena Maddukuri, Robert L. Eoff, Megan R. Reed
Publikováno v:
ACS Chem Biol
Overexpression of human DNA polymerase kappa (hpol κ) in glioblastoma is associated with shorter survival time and resistance to the alkylating agent temozolomide (TMZ), making it an attractive target for the development of small-molecule inhibitors
Autor:
Maroof K. Zafar, Leena Maddukuri, Robert L. Eoff, Amit Ketkar, Stephanie D. Byrum, Alan J. Tackett, April C.L. Bostian, Megan R. Reed
Publikováno v:
Nar Cancer
Expression of tryptophan 2,3-dioxygenase (TDO) is a determinant of malignancy in gliomas through kynurenine (KYN) signaling. We report that inhibition of TDO activity attenuated recovery from replication stress and increased the genotoxic effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b6a536ca8038d6c8cc55a6c11f9dbc
https://doi.org/10.1101/2020.05.28.110874
https://doi.org/10.1101/2020.05.28.110874