Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Amit K Keshari"'
Autor:
Archana Bharti Sonkar, Abhishek Verma, Sneha Yadav, Rohit Kumar, Jyoti Singh, Amit K. Keshari, Soniya Rani, Anurag Kumar, Dharmendra Kumar, Neeraj Kumar Shrivastava, Shubham Rastogi, Mariam K. Alamoudi, Mohd Nazam Ansari, Abdulaziz S. Saeedan, Gaurav Kaithwas, Sudipta Saha
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Lung cancer (LC) ranks second most prevalent cancer in females after breast cancer and second in males after prostate cancer. Based on the GLOBOCAN 2020 report, India represented 5.9% of LC cases and 8.1% of deaths caused by the disease. Sev
Externí odkaz:
https://doaj.org/article/75ea3dd802f64ea79952ff6c520d7a14
Autor:
Atul Rawat, Durgesh Dubey, Anupam Guleria, Umesh Kumar, Amit K Keshari, Swati Chaturvedi, Anand Prakash, Sudipta Saha, Dinesh Kumar
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 8, Iss 4, Pp 327-334 (2016)
Introduction: Erythromycin (ERY) is known to induce hepatic toxicity which mimics other liver diseases. Thus, ERY is often used to produce experimental models of drug-induced liver-toxicity. The serum metabolic profiles can be used to evaluate the li
Externí odkaz:
https://doaj.org/article/71a0a7f9b242476cada3b658075252db
Autor:
Archana Bharti Sonkar, Pranesh Kumar, Anand Kumar, Anurag Kumar Gautam, Abhishek Verma, Amita Singh, Umesh Kumar, Dinesh Kumar, Tarun Mahata, Bolay Bhattacharya, Amit K. Keshari, Biswanath Maity, Sudipta Saha
Publikováno v:
International Immunopharmacology. 119:110236
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::041bc23c2f10769f9d2a3c931e7f7c8a
https://doi.org/10.1016/j.intimp.2023.110236
https://doi.org/10.1016/j.intimp.2023.110236
Autor:
Swati Chaturvedi, Ashok K. Singh, Amit K. Keshari, Siddhartha Maity, Srimanta Sarkar, Sudipta Saha
Publikováno v:
Scientifica, Vol 2016 (2016)
One of the extreme challenges in biology is to ameliorate the understanding of the mechanisms which emphasize metabolic enzyme deficiency (MED) and how these pretend to have influence on human health. However, it has been manifested that MED could be
Externí odkaz:
https://doaj.org/article/c453ba8a8c7e4d858df7db9f5ff017a5
Autor:
Sudipta Saha, Vinit Raj, Ashok K. Singh, Amit Rai, Amit K Keshari, Mohamed H. Aboumanei, Suraj P. Verma
Publikováno v:
Pharmaceutical Chemistry Journal. 54:12-25
Interleukin-6 (IL-6) is the new molecular target to treat colorectal cancer (CRC) for investigation of potential lead molecules. The main objective of this study was to develop the three-dimensional quantitative structure – activity relationship (3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fe1643959de2fd68f7b56ab3d719403
https://doi.org/10.1007/s11094-020-02149-3
https://doi.org/10.1007/s11094-020-02149-3
Autor:
Anurag Kumar Gautam, Himani Tiwari, Abhishek Verma, Shubham Yadav, Nanda Gopal Sahoo, Amita Singh, Amit K Keshari, Pranesh Kumar, Sudipta Saha, Archana Bharti Sonkar, Biswanath Maity
Publikováno v:
Mini reviews in medicinal chemistry.
PCSK9 is a strongly expressed protein in the liver and brain that binds to the LDLR and regulates cholesterol in the liver effectively. Other receptors with which it interacts include VLDLR, LRP1, ApoER2, and OLR1. PCSK9 gain-of-function results in l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd953687061fa128214039a2b7155060
https://pubmed.ncbi.nlm.nih.gov/34856898
https://pubmed.ncbi.nlm.nih.gov/34856898
Autor:
Amit Rai, Archana S. Bhadauria, Umesh Kumar, Kausar M. Ansari, Pranesh Kumar, Anand Prakash, Vinit Raj, Sudipta Saha, Sneha Nath, Biswanath Maity, Amit K Keshari, Jawahar L. Jat, Dinesh Kumar, Ashok K. Singh
Publikováno v:
Cytokine. 118:144-159
We attempted a preclinical study using DMH-induced CRC rat model to evaluate the antitumor potential of our recently synthesized 1,3,4-thiadiazoles. The molecular insights were confirmed through ELISA, qRT-PCR and western blot analyses. The CRC condi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e654538579bfe43525cb4b4f8f436d6f
https://doi.org/10.1016/j.cyto.2018.03.026
https://doi.org/10.1016/j.cyto.2018.03.026
Publikováno v:
Cogent Chemistry, Vol 3, Iss 1 (2017)
In this study, we designed and synthesized a series of 1,4-benzothiazine and evaluated them for anticancer activity toward HT-29 human colon cancer cells using SRB assay. Before the synthesis, docking studies were performed using various molecular ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e816ed0c74c52cfa1aab8f50b83f538
Autor:
Abdul Hafeez, Khalid Saad Alharbi, Kriti Soni, Md. Habban Akhter, Nisha Sharma, Amit K Keshari, Sarwar Beg, Habibullah Khalilullah, Tanuja Singh, Saad Alghamdi, Waleed H. Almalki, Mahfoozur Rahman
Publikováno v:
Drug discovery today. 26(11)
The development of pharmaceutical drug products is required for the treatment of disease, which has resulted in an increasing number of approvals by regulatory agencies across the globe. To establish a hassle-free manufacturing process, the systemati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6b5518c7c76b8c54defae0f3105e29
https://pubmed.ncbi.nlm.nih.gov/34242795
https://pubmed.ncbi.nlm.nih.gov/34242795
Autor:
Biswanath Maity, Amit Rai, Sudipta Saha, Archana S. Bhadauria, Anand Prakash, Pranesh Kumar, Sneha Nath, Vinit Raj, Dinesh Kumar, Umesh Kumar, Amit K Keshari, Ashok K. Singh
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-2 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-2 (2020)
Inspired by the well-documented tumor protecting ability of paullones, recently, we synthesized novel paullone-like scaffolds, indole-fused benzo-oxazepines (IFBOs), and screened them against hepatocellular carcinoma (HCC) specific Hep-G2 cells. Thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b73d9cbb4c19bdc1cb1eba33543a19
https://doi.org/10.1038/s41598-020-59134-9
https://doi.org/10.1038/s41598-020-59134-9