Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Amit Fulzele"'
Autor:
Rutuja Kuhikar, Nikhat Khan, Satyajeet P. Khare, Amit Fulzele, Sameer Melinkeri, Vaijayanti Kale, Lalita Limaye
Publikováno v:
Stem Cell Research, Vol 50, Iss , Pp 102150- (2021)
Neutrophils release neutrophil extracellular traps (NET) comprising of decondensed chromatin that immobilizes and kills pathogens. In vitro generation of neutrophils on a large scale from hematopoietic stem cells (HSCs) may be a useful strategy for t
Externí odkaz:
https://doaj.org/article/a9d866b56277400282479a6fcba4b135
Autor:
Niladri K Sinha, Alban Ordureau, Katharina Best, James A Saba, Boris Zinshteyn, Elayanambi Sundaramoorthy, Amit Fulzele, Danielle M Garshott, Timo Denk, Matthias Thoms, Joao A Paulo, J Wade Harper, Eric J Bennett, Roland Beckmann, Rachel Green
Publikováno v:
eLife, Vol 9 (2020)
Translation of aberrant mRNAs induces ribosomal collisions, thereby triggering pathways for mRNA and nascent peptide degradation and ribosomal rescue. Here we use sucrose gradient fractionation combined with quantitative proteomics to systematically
Externí odkaz:
https://doaj.org/article/900a514023304981b6374d2c536978ff
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Toll mediates a robust and effective innate immune response across vertebrates and invertebrates. In Drosophila melanogaster, activation of Toll by systemic infection drives the accumulation of a rich repertoire of immune effectors in hemolymph, incl
Externí odkaz:
https://doaj.org/article/d671fe81218a4beba847cde5412c6796
Autor:
Shaunak Deota, Tandrika Chattopadhyay, Deepti Ramachandran, Eric Armstrong, Beatriz Camacho, Babukrishna Maniyadath, Amit Fulzele, Anne Gonzalez-de-Peredo, John M. Denu, Ullas Kolthur-Seetharam
Publikováno v:
Cell Reports, Vol 18, Iss 13, Pp 3069-3077 (2017)
The conserved NAD+-dependent deacylase SIRT1 plays pivotal, sometimes contrasting, roles in diverse physiological and pathophysiological conditions. In this study, we uncover a tissue-restricted isoform of SIRT1 (SIRT1-ΔE2) that lacks exon 2 (E2). C
Externí odkaz:
https://doaj.org/article/d70d0f1bf76d456f9a04c4942aa3c53d
Autor:
Sebastian Markmiller, Amit Fulzele, Reneé Higgins, Marilyn Leonard, Gene W. Yeo, Eric J. Bennett
Publikováno v:
Cell Reports, Vol 27, Iss 5, Pp 1356-1363.e3 (2019)
Summary: Stress granule (SG) formation is frequently accompanied by ubiquitin proteasome system (UPS) impairment and ubiquitylated protein accumulation. SGs, ubiquitin, and UPS components co-localize, but the relationship between the ubiquitin pathwa
Externí odkaz:
https://doaj.org/article/feb76962d473497d98635e99f998b361
Autor:
Satarupa Bhaduri, Analine Aguayo, Yusuke Ohno, Marco Proietto, Jasmine Jung, Isabel Wang, Rachel Kandel, Narinderbir Singh, Ikran Ibrahim, Amit Fulzele, Eric Bennett, Akio Kihara, Sonya E. Neal
Publikováno v:
The EMBO Journal. 42
SUMMARYNearly one-third of nascent proteins are initially targeted to the endoplasmic reticulum (ER) where they are correctly folded and assembled before being delivered to their final cellular destinations. To prevent the accumulation of misfolded m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29a8b25c1df6cac5029d8b582bc027c
https://doi.org/10.15252/embj.2022112275
https://doi.org/10.15252/embj.2022112275
Autor:
Tim Nicholson-Shaw, Yasmeen Ajaj, Mark Perelis, Amit Fulzele, Gene W. Yeo, Eric J. Bennett, Jens Lykke-Andersen
SummaryThe Ribosome-associated Quality Control (RQC) pathway serves to resolve ribosomes stalled during the translation process and degrade the associated mRNA and nascent polypeptide. Here we identify the 2’,3’ cyclic phosphatase Angel1 as a rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84f16ae857698221e79ee0563105aca4
https://doi.org/10.1101/2022.04.28.489582
https://doi.org/10.1101/2022.04.28.489582
Autor:
Qiong Nan, Hong Liang, Janette Mendoza, Le Liu, Amit Fulzele, Amanda Wright, Eric J Bennett, Carolyn G Rasmussen, Michelle R Facette
Asymmetric divisions produce cells with different fates and are critical for development. Here we show that a maize myosin XI protein, OPAQUE1 (O1), is necessary for asymmetric divisions during maize stomatal development. We analyzed stomatal precurs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b8083bbac6c23bbed96a1a5cb9cc60
https://doi.org/10.1101/2021.08.29.458084
https://doi.org/10.1101/2021.08.29.458084
Autor:
Karl L, Banta, Xiaozheng, Xu, Avantika S, Chitre, Amelia, Au-Yeung, Chikara, Takahashi, William E, O'Gorman, Thomas D, Wu, Stephanie, Mittman, Rafael, Cubas, Laetitia, Comps-Agrar, Amit, Fulzele, Eric J, Bennett, Jane L, Grogan, Enfu, Hui, Eugene Y, Chiang, Ira, Mellman
Publikováno v:
Immunity. 55(3)
Dual blockade of the PD-1 and TIGIT coinhibitory receptors on T cells shows promising early results in cancer patients. Here, we studied the mechanisms whereby PD-1 and/or TIGIT blockade modulate anti-tumor CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d237098913f41245956df8c61565e97
https://pubmed.ncbi.nlm.nih.gov/35263569
https://pubmed.ncbi.nlm.nih.gov/35263569
Autor:
Karl L. Banta, Xiaozheng Xu, Avantika S. Chitre, Amelia Au-Yeung, Chikara Takahashi, William E. O’Gorman, Thomas D. Wu, Stephanie Mittman, Rafael Cubas, Laetitia Comps-Agrar, Amit Fulzele, Eric J. Bennett, Jane L. Grogan, Enfu Hui, Eugene Y. Chiang, Ira Mellman
Publikováno v:
Immunity. 55:512-526.e9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3942a7e957a961c22110f86bd394d059
https://doi.org/10.1016/j.immuni.2022.02.005
https://doi.org/10.1016/j.immuni.2022.02.005