Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Amit Deorukhkar"'
Autor:
Carolina J. Garcia Garcia, Yanqing Huang, Natividad R. Fuentes, Madeleine C. Turner, Maria E. Monberg, Daniel Lin, Nicholas D. Nguyen, Tara N. Fujimoto, Jun Zhao, Jaewon J. Lee, Vincent Bernard, Meifang Yu, Abagail M. Delahoussaye, Iancarlos Jimenez Sacarello, Emily G. Caggiano, Jae L. Phan, Amit Deorukhkar, Jessica M. Molkentine, Dieter Saur, Anirban Maitra, Cullen M. Taniguchi
Publikováno v:
Gastroenterology. 162:2018-2031
Pancreatic ductal adenocarcinoma (PDAC) has a hypoxic, immunosuppressive stroma that contributes to its resistance to immune checkpoint blockade therapies. The hypoxia-inducible factors (HIFs) mediate the cellular response to hypoxia, but their role
Autor:
Sushovan Guha, Christopher R. Ireson, Enrique Rozengurt, Bharat B. Aggarwal, Sunil Krishnan, Juri Gelovani, James Sinnett-Smith, Yoichi Matsuo, Parmeswaran Diagaradjane, Dipen Maru, Muddasar Farooq, Alexandra Boakes, Caroline Foxton, Azadeh Bagherzadeh, Mark Charles, Tony Raynham, Rachel Sutherland, Stephen Jamieson, Lloyd Kelland, Bokyung Sung, Amit Deorukhkar, Zhimin Tong, Nobuo Ochi, Ajaikumar B. Kunnumakkara, Kuzhuvelil B. Harikumar
Protein kinase D (PKD) family members are increasingly implicated in multiple normal and abnormal biological functions, including signaling pathways that promote mitogenesis in pancreatic cancer. However, nothing is known about the effects of targeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab32f00e1cc289882edd000632bf0373
https://doi.org/10.1158/1535-7163.c.6531675.v1
https://doi.org/10.1158/1535-7163.c.6531675.v1
Autor:
Bharat B. Aggarwal, Sushovan Guha, Sunil Krishnan, Veerabhadran Baladandayuthapani, Caimiao Wei, Parmeswaran Diagaradjane, Amit Deorukhkar, Ramaswamy Kannappan, Simone Reuter, Bokyung Sung, Vivek R. Yadav, Sahdeo Prasad
Purpose: Development of chemoresistance, poor prognosis, and metastasis often renders the current treatments for colorectal cancer (CRC) ineffective. Whether ursolic acid, a component of numerous medicinal plants, either alone or in combination with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa8b427f30e8633d926900cb2af68c6
https://doi.org/10.1158/1078-0432.c.6519765.v1
https://doi.org/10.1158/1078-0432.c.6519765.v1
Autor:
Cullen M. Taniguchi, Anirban Maitra, Helen Piwnica-Worms, Eugene J. Koay, Gabriel O. Sawakuchi, Ramesh C. Tailor, Charles V. Kingsley, Peter K. Cabeceiras, Sonal Gupta, Daniel Lin, Meifang Yu, Marimar de la Cruz Bonilla, Laura Baseler, Amit Deorukhkar, Jessica M. Molkentine, Yanqing Huang, Lauren E. Colbert, Tara N. Fujimoto
When pancreatic cancer cannot be removed surgically, patients frequently experience morbidity and death from progression of their primary tumor. Radiation therapy (RT) cannot yet substitute for an operation because radiation causes fatal bleeding and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e9e981d1e0bbb09e43758dbdf49b9f0
https://doi.org/10.1158/0008-5472.c.6511569.v1
https://doi.org/10.1158/0008-5472.c.6511569.v1
Autor:
Cullen M. Taniguchi, Anirban Maitra, Helen Piwnica-Worms, Eugene J. Koay, Gabriel O. Sawakuchi, Ramesh C. Tailor, Charles V. Kingsley, Peter K. Cabeceiras, Sonal Gupta, Daniel Lin, Meifang Yu, Marimar de la Cruz Bonilla, Laura Baseler, Amit Deorukhkar, Jessica M. Molkentine, Yanqing Huang, Lauren E. Colbert, Tara N. Fujimoto
Figure S4. Metabolic cage analysis of mice treated with a clinically relevant course of dose-escalated RT to a limited upper abdominal field. (A) Water consumed during fractionated radiation treatments with area under the curve quantification in (B)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5137355a6eccc76ce882479686962559
https://doi.org/10.1158/0008-5472.22423731.v1
https://doi.org/10.1158/0008-5472.22423731.v1
Autor:
Bharat B. Aggarwal, Sushovan Guha, Sunil Krishnan, Veerabhadran Baladandayuthapani, Caimiao Wei, Parmeswaran Diagaradjane, Amit Deorukhkar, Ramaswamy Kannappan, Simone Reuter, Bokyung Sung, Vivek R. Yadav, Sahdeo Prasad
PDF file, 52K, Assessment of synergistic drug combination treatments between ursolic acid and capecitabine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0188a416a1160c8235ddbe8d0124fb4a
https://doi.org/10.1158/1078-0432.22443306
https://doi.org/10.1158/1078-0432.22443306
Autor:
Sunil Krishnan, Juri G. Gelovani, David L. Schwartz, Norihito Kuno, Shujun Shentu, Amit Deorukhkar, Norman E. Colón-Casasnovas, Jacobo M. Orenstein-Cardona, Parmeswaran Diagaradjane
Supplementary Figures S1-S3 from Imaging Epidermal Growth Factor Receptor Expression In vivo: Pharmacokinetic and Biodistribution Characterization of a Bioconjugated Quantum Dot Nanoprobe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::730097b7160dcb0b986a51c2b0b554fc
https://doi.org/10.1158/1078-0432.22441128.v1
https://doi.org/10.1158/1078-0432.22441128.v1
Autor:
Cullen M. Taniguchi, Anirban Maitra, Helen Piwnica-Worms, Eugene J. Koay, Gabriel O. Sawakuchi, Ramesh C. Tailor, Charles V. Kingsley, Peter K. Cabeceiras, Sonal Gupta, Daniel Lin, Meifang Yu, Marimar de la Cruz Bonilla, Laura Baseler, Amit Deorukhkar, Jessica M. Molkentine, Yanqing Huang, Lauren E. Colbert, Tara N. Fujimoto
Table S1. Distribution of Tumor and Treatment Characteristics for All Enrolled Animals by Treatment Group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a959e797fdadd0effe244130546069
https://doi.org/10.1158/0008-5472.22423725.v1
https://doi.org/10.1158/0008-5472.22423725.v1
Autor:
Sushovan Guha, Christopher R. Ireson, Enrique Rozengurt, Bharat B. Aggarwal, Sunil Krishnan, Juri Gelovani, James Sinnett-Smith, Yoichi Matsuo, Parmeswaran Diagaradjane, Dipen Maru, Muddasar Farooq, Alexandra Boakes, Caroline Foxton, Azadeh Bagherzadeh, Mark Charles, Tony Raynham, Rachel Sutherland, Stephen Jamieson, Lloyd Kelland, Bokyung Sung, Amit Deorukhkar, Zhimin Tong, Nobuo Ochi, Ajaikumar B. Kunnumakkara, Kuzhuvelil B. Harikumar
Supplementary Data from A Novel Small-Molecule Inhibitor of Protein Kinase D Blocks Pancreatic Cancer Growth In vitro and In vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146fb75ff91e4ab866310a4198e944e7
https://doi.org/10.1158/1535-7163.22484955
https://doi.org/10.1158/1535-7163.22484955
Autor:
Sunil Krishnan, Juri G. Gelovani, David L. Schwartz, Norihito Kuno, Shujun Shentu, Amit Deorukhkar, Norman E. Colón-Casasnovas, Jacobo M. Orenstein-Cardona, Parmeswaran Diagaradjane
Purpose: To develop and validate an optical imaging nanoprobe for the discrimination of epidermal growth factor (EGF) receptor (EGFR)–overexpressing tumors from surrounding normal tissues that also expresses EGFR.Experimental Design: Near-infrared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2622902aa3a5025595ee571323821456
https://doi.org/10.1158/1078-0432.c.6518280
https://doi.org/10.1158/1078-0432.c.6518280