Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Amit D. Amin"'
Autor:
Jonathan H. Schatz, Eli Chapman, Abimael D. Rodríguez, Graham Packham, Cyril H. Benes, Francisco Vega, Patricia Greninger, Gillian Paine-Murrieta, Andrew J. Ambrose, Christopher J. Zerio, Praechompoo Pongtornpipat, Amit D. Amin, Lingxiao Li, Luis A. Amador, Carlos Jiménez-Romero, Elizabeth Lemm, Sarah Wilmore, Alison M. Yeomans, Joseph Tillotson, Tara L. Peters
Figure S1. Elatol was submitted to a 96-member kinome screen to evaluate specificity. Figure S2. A) Michaelis-Menten curves of eIF4A1 wild type (blue), K82R (red), and K238E (green). Michaelis- Menten constants for eIF4A1 wild type and mutants in tab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b0c08aa1ad75e37b8b895a22244a71
https://doi.org/10.1158/1078-0432.22469778.v1
https://doi.org/10.1158/1078-0432.22469778.v1
Autor:
Jonathan H. Schatz, Eli Chapman, Abimael D. Rodríguez, Graham Packham, Cyril H. Benes, Francisco Vega, Patricia Greninger, Gillian Paine-Murrieta, Andrew J. Ambrose, Christopher J. Zerio, Praechompoo Pongtornpipat, Amit D. Amin, Lingxiao Li, Luis A. Amador, Carlos Jiménez-Romero, Elizabeth Lemm, Sarah Wilmore, Alison M. Yeomans, Joseph Tillotson, Tara L. Peters
Purpose: The DEAD-box RNA helicase eIF4A1 carries out the key enzymatic step of cap-dependent translation initiation and is a well-established target for cancer therapy, but no drug against it has entered evaluation in patients. We identified and cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0a4100a7388fdcb4d088138f676666
https://doi.org/10.1158/1078-0432.c.6527340
https://doi.org/10.1158/1078-0432.c.6527340