Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Amit Awasthi"'
Autor:
Tannu Priya Gosain, Saurabh Chugh, Zaigham Abbas Rizvi, Neeraj Kumar Chauhan, Saqib Kidwai, Krishan Gopal Thakur, Amit Awasthi, Ramandeep Singh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The genome of Mycobacterium tuberculosis encodes for a large repertoire of toxin-antitoxin systems. In the present study, MenT3 and MenT4 toxins belonging to MenAT subfamily of TA systems have been functionally characterized. We demonstrate
Externí odkaz:
https://doaj.org/article/1cfe23946fcc4272ad091ea4e17742c3
Autor:
Akshay Binayke, Aymaan Zaheer, Siddhesh Vishwakarma, Savita Singh, Priyanka Sharma, Rucha Chandwaskar, Mudita Gosain, Sreevatsan Raghavan, Deepika Rathna Murugesan, Pallavi Kshetrapal, Ramachandran Thiruvengadam, Shinjini Bhatnagar, Anil Kumar Pandey, Pramod Kumar Garg, Amit Awasthi
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Measuring SARS-CoV-2-specific T cell responses is crucial to understanding an individual’s immunity to COVID-19. However, high inter- and intra-assay variability make it difficult to define T cells as a correlate of protection against COVI
Externí odkaz:
https://doaj.org/article/5a6d005e8b2742bfa6b784ecc60e6d74
VapC12 ribonuclease toxin modulates host immune response during Mycobacterium tuberculosis infection
Autor:
Shaifali Tyagi, Srikanth Sadhu, Taruna Sharma, Abhijit Paul, Manitosh Pandey, Vaibhav Kumar Nain, Deepak Kumar Rathore, Samrat Chatterjee, Amit Awasthi, Amit Kumar Pandey
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Mechanistic understanding of antibiotic persistence is a prerequisite in controlling the emergence of MDR cases in Tuberculosis (TB). We have reported that the cholesterol-induced activation of VapC12 ribonuclease is critical for disease persistence
Externí odkaz:
https://doaj.org/article/f16038945c2344a38c75ef56c196a00b
Autor:
Ramachandran Thiruvengadam, Zaigham Abbas Rizvi, Sreevatsan Raghavan, Deepika Rathna Murugesan, Mudita Gosain, Jyotsna Dandotiya, Ayushi, Sweety Samal, Anil K. Pandey, Nitya Wadhwa, Shinjini Bhatnagar, Amit Awasthi, Pramod Kumar Garg
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-8 (2023)
Abstract Objectives To study clinical disease outcomes in both human and animal models to understand the pathogenicity of omicron compared to the delta variant. Methods In this cross-sectional observational study, clinical outcomes of adults who test
Externí odkaz:
https://doaj.org/article/add37760135443dfa55c27b3634eb0b6
Autor:
Zaigham Abbas Rizvi, Jyotsna Dandotiya, Srikanth Sadhu, Ritika Khatri, Janmejay Singh, Virendra Singh, Neeta Adhikari, Kritika Sharma, Vinayake Das, Amit Kumar Pandey, Bhabatosh Das, Guruprasad Medigeshi, Shalendra Mani, Shinjini Bhatnagar, Sweety Samal, Anil Kumar Pandey, Pramod Kumar Garg, Amit Awasthi
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract A recently emerged sub-lineage of Omicron, BA.5, together with BA.4, caused a fifth wave of coronavirus disease (COVID-19) in South Africa and subsequently emerged as a predominant strain globally due to its high transmissibility. The lethal
Externí odkaz:
https://doaj.org/article/fa2213b252c144c39434f971c7aca2bd
Autor:
Srikanth Sadhu, Rajdeep Dalal, Jyotsna Dandotiya, Akshay Binayke, Virendra Singh, Manas Ranjan Tripathy, Vinayaka Das, Sandeep Goswami, Shakti Kumar, Zaigham Abbas Rizvi, Amit Awasthi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract SARS-CoV-2 infection is known for causing broncho-alveolar inflammation. Interleukin 9 (IL-9) induces airway inflammation and bronchial hyper responsiveness in respiratory viral illnesses and allergic inflammation, however, IL-9 has not been
Externí odkaz:
https://doaj.org/article/04743ba11185487a96108ea58019d13c
Publikováno v:
Frontiers in Environmental Science, Vol 11 (2023)
Introduction: The significant impact of climate change on temperature is an important topic of discussion as it rises globally. Hence, the present study is designed to investigate the profound influence of climate change on temperature by considering
Externí odkaz:
https://doaj.org/article/db82412387a34b77ba71e5229e02452f
Autor:
Shuvra Shekhar Roy, Shalu Sharma, Zaigham Abbas Rizvi, Dipanjali Sinha, Divya Gupta, Mercy Rophina, Paras Sehgal, Srikanth Sadhu, Manas Ranjan Tripathy, Sweety Samal, Souvik Maiti, Vinod Scaria, Sridhar Sivasubbu, Amit Awasthi, Krishnan H. Harshan, Sanjeev Jain, Shantanu Chowdhury
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
The COVID-19 pandemic caused by SARS-CoV-2 has caused millions of infections and deaths worldwide. Limited treatment options and the threat from emerging variants underline the need for novel and widely accessible therapeutics. G-quadruplexes (G4s) a
Externí odkaz:
https://doaj.org/article/be185dc57a37426ca40b3079c5373adf
Autor:
Zaigham Abbas Rizvi, Prabhakar Babele, Upasna Madan, Srikanth Sadhu, Manas Ranjan Tripathy, Sandeep Goswami, Shailendra Mani, Madhu Dikshit, Amit Awasthi
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cytokine release syndrome (CRS) due to severe acute respiratory coronavirus-2 (SARS-CoV-2) infection leads to life-threatening pneumonia which has been associated with coronavirus disease (COVID-19) pathologies. Centuries-old Asian traditional medici
Externí odkaz:
https://doaj.org/article/98d95fd42fa24d40b82561b1cd7ed89a
Autor:
Zaigham Abbas Rizvi, Upasna Madan, Manas Ranjan Tripathy, Sandeep Goswami, Shailendra Mani, Amit Awasthi, Madhu Dikshit
Publikováno v:
Pharmaceuticals, Vol 16, Iss 9, p 1333 (2023)
In the current study, we evaluated the efficacy of Ayush-64 (A64), a polyherbal formulation containing Alstonia scholaris (L.) R. Br. (A. scholaris), Caesalpinia crista L. (C. crista), Picrorhiza kurroa Royle ex Benth (P. kurroa), and Swertia chirata
Externí odkaz:
https://doaj.org/article/cdd23c41038b4f1fa955a9a3789deb29