Factors affecting the electrocardiographic QT interval in malaria: A systematic review and meta-analysis of individual patient data.

Autor: Xin Hui S Chan, Yan Naung Win, Ilsa L Haeusler, Jireh Y Tan, Shanghavie Loganathan, Sompob Saralamba, Shu Kiat S Chan, Elizabeth A Ashley, Karen I Barnes, Rita Baiden, Peter U Bassi, Abdoulaye Djimde, Grant Dorsey, Stephan Duparc, Borimas Hanboonkunupakarn, Feiko O Ter Kuile, Marcus V G Lacerda, Amit Nasa, François H Nosten, Cyprian O Onyeji, Sasithon Pukrittayakamee, André M Siqueira, Joel Tarning, Walter R J Taylor, Giovanni Valentini, Michèle van Vugt, David Wesche, Nicholas P J Day, Christopher L-H Huang, Josep Brugada, Ric N Price, Nicholas J White

Publikováno v: PLoS Medicine, Vol 17, Iss 3, p e1003040 (2020)

BackgroundElectrocardiographic QT interval prolongation is the most widely used risk marker for ventricular arrhythmia potential and thus an important component of drug cardiotoxicity assessments. Several antimalarial medicines are associated with QT

Externí odkaz: https://doaj.org/article/8ea6d1a043354012a21da11481816ea6

Efficacy and safety of fixed dose combination of arterolane maleate and piperaquine phosphate in comparison with chloroquine phosphate in children with acute uncomplicated

Autor: Neena, Valecha, Vimal Kant, Goyal, Deo Nidhi, Mishra, Rashmi Ranjan, Das, Neeraj, Jauhri, Alok Chandra, Bhardwaj, Omesh, Khurana, Reena, Choudhury, Madhukar, Pandey, Bantwal Shantharam, Baliga, Susanta Kumar, Ghosh, Bina, Srivastava, Santhosh T, Soans, Raj Kamal, Bahl, Ajay, Punj, Arjun, Roy, Sanjay K, Sharma, Amit, Nasa, Rajinder K, Jalali, Anupkumar R, Anvikar

Publikováno v: Journal of vector borne diseases. 57(3)

In India, the burden of Plasmodium vivax malaria has been projected to be highest in some areas. This study investigated the efficacy and safety of fixed dose combination (FDC) of arterolane maleate (AM) 37.5 mg and piperaquine phosphate 187.5 mg (PQ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4ecdf92a9cff161cac5c7316e4832822
https://pubmed.ncbi.nlm.nih.gov/34472504

Assessment of Efficacy and Safety of Arterolane Maleate-Piperaquine Phosphate Dispersible Tablets in Comparison With Artemether-Lumefantrine Dispersible Tablets in Pediatric Patients With Acute Uncomplicated Plasmodium falciparum Malaria: A Phase 3, Randomized, Multicenter Trial in India and Africa

Autor: Offianan Andre, Toure, Victor, Mwapasa, Issaka, Sagara, Oumar, Gaye, Ricardo, Thompson, Aishwarya V, Maheshwar, Pitabas, Mishra, Narendra, Behra, Antoinette K, Tshefu, Rashmi R, Das, Anupkumar R, Anvikar, Pradeep, Sharma, Arjun, Roy, Sanjay K, Sharma, Amit, Nasa, Rajinder K, Jalali, Neena, Valecha, Goutam, Patel

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 65(10)

Administration of artemisinin-based combination therapy (ACT) to infant and young children can be challenging. A formulation with accurate dose and ease of administration will improve adherence and compliance in children. The fixed-dose combination d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::05e30f49e858e8e6741616a5add52b37
https://pubmed.ncbi.nlm.nih.gov/29020247

Factors affecting the electrocardiographic QT interval in malaria: A systematic review and meta-analysis of individual patient data.

Autor: Chan, Xin Hui S.^1,2 (AUTHOR) xinhui@tropmedres.ac, Win, Yan Naung^1,3 (AUTHOR), Haeusler, Ilsa L.^4,5 (AUTHOR), Tan, Jireh Y.¹ (AUTHOR), Loganathan, Shanghavie^1,6 (AUTHOR), Saralamba, Sompob¹ (AUTHOR), Chan, Shu Kiat S.^1,7 (AUTHOR), Ashley, Elizabeth A.^2,8 (AUTHOR), Barnes, Karen I.^9,10 (AUTHOR), Baiden, Rita¹¹ (AUTHOR), Bassi, Peter U.¹² (AUTHOR), Djimde, Abdoulaye¹³ (AUTHOR), Dorsey, Grant¹⁴ (AUTHOR), Duparc, Stephan¹⁵ (AUTHOR), Hanboonkunupakarn, Borimas^1,16 (AUTHOR), ter Kuile, Feiko O.¹⁷ (AUTHOR), Lacerda, Marcus V. G.^18,19 (AUTHOR), Nasa, Amit²⁰ (AUTHOR), Nosten, François H.^2,21 (AUTHOR), Onyeji, Cyprian O.²² (AUTHOR)

Publikováno v: PLoS Medicine. 3/5/2020, Vol. 17 Issue 3, p1-20. 20p. 1 Diagram, 3 Charts, 3 Graphs.

Assessment of Efficacy and Safety of Arterolane Maleate-Piperaquine Phosphate Dispersible Tablets in Comparison With Artemether-Lumefantrine Dispersible Tablets in Pediatric Patients With Acute Uncomplicated Plasmodium falciparum Malaria: A Phase 3, Randomized, Multicenter Trial in India and Africa

Autor: Toure, Offianan Andre, Mwapasa, Victor, Sagara, Issaka, Gaye, Oumar, Thompson, Ricardo, Maheshwar, Aishwarya V., Mishra, Pitabas, Behra, Narendra, Tshefu, Antoinette K., Das, Rashmi R., Anvikar, Anupkumar R., Sharma, Pradeep, Roy, Arjun, Sharma, Sanjay K., Nasa, Amit, Jalali, Rajinder K., Valecha, Neena

Publikováno v: Clinical Infectious Diseases; 11/15/2017, Vol. 65 Issue 10, p1711-1720, 10p