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Expression of a Novel Chimeric-Truncated tPA in Pichia pastoris with Improved Biochemical Properties
Autor:
Mohammadreza Kazemali, Fatemeh Davami, Farzaneh Barkhordari, Ahmad Adeli, Najmeh Zarei, Soroush Sardari, Fereidoun Mahboudi, Amirhossein Saadatirad
Publikováno v:
Molecular Biotechnology. 56:1143-1150
Thrombolytic therapy by plasminogen activators (PAs) has been a main goal in the treatment of acute myocardial infarction. Despite improved outcomes of currently available thrombolytic therapies, all these agents have different drawbacks that may res