Asymmetric depth‐filtration: A versatile and scalable method for high‐yield isolation of extracellular vesicles with low contamination

Autor: Vasiliy S. Chernyshev, Roman N. Chuprov‐Netochin, Ekaterina Tsydenzhapova, Elena V. Svirshchevskaya, Rimma A. Poltavtseva, Anastasiia Merdalimova, Alexey Yashchenok, Amiran Keshelava, Konstantin Sorokin, Varlam Keshelava, Gennadiy T. Sukhikh, Dmitry Gorin, Sergey Leonov, Mikhail Skliar

Publikováno v: Journal of Extracellular Vesicles, Vol 11, Iss 8, Pp n/a-n/a (2022)

Abstract We developed a novel asymmetric depth filtration (DF) approach to isolate extracellular vesicles (EVs) from biological fluids that outperforms ultracentrifugation and size‐exclusion chromatography in purity and yield of isolated EVs. By th

Externí odkaz: https://doaj.org/article/459249d3d7d043f38926da03a6435d9a

Identification of novel elements of the Drosophila blisterome sheds light on potential pathological mechanisms of several human diseases.

Autor: Oleksii Bilousov, Alexey Koval, Amiran Keshelava, Vladimir L Katanaev

Publikováno v: PLoS ONE, Vol 9, Iss 6, p e101133 (2014)

Main developmental programs are highly conserved among species of the animal kingdom. Improper execution of these programs often leads to progression of various diseases and disorders. Here we focused on Drosophila wing tissue morphogenesis, a fairly

Externí odkaz: https://doaj.org/article/dae44ba8c5274a5889ac89bc74a52e4c

High capacity in G protein-coupled receptor signaling

Autor: Alexey Koval, Sven Bergmann, Amiran Keshelava, Vladimir L. Katanaev, Mikhail Kryuchkov, Gonzalo P. Solis, Micha Hersch

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Nature Communications, Vol. 9, No 1 (2018) P. 876
Nature Communications
Nature communications, vol. 9, no. 1, pp. 876

G protein-coupled receptors (GPCRs) constitute a large family of receptors that activate intracellular signaling pathways upon detecting specific extracellular ligands. While many aspects of GPCR signaling have been uncovered through decades of studi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee81ab46ceaeb5fd3835ad768bf9603
https://doaj.org/article/e2b10c70e16e40f196b3c188a5647db1

Identification of novel elements of the Drosophila blisterome sheds light on potential pathological mechanisms of several human diseases

Autor: Vladimir L. Katanaev, Oleksii Bilousov, Alexey Koval, Amiran Keshelava

Publikováno v: PLoS ONE
Plos One, vol. 9, no. 6, pp. e101133
PLoS ONE, Vol 9, Iss 6, p e101133 (2014)

Main developmental programs are highly conserved among species of the animal kingdom. Improper execution of these programs often leads to progression of various diseases and disorders. Here we focused on Drosophila wing tissue morphogenesis, a fairly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f1cd0ec560453c2842667e61aa5633
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072764/