Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Amira S. Gouda"'
Autor:
Rania Elkeeb, Anomeh Avartoomian, Amira S. Gouda, Ahmed M. Abdel-Megied, Ola Abdallah, Eman Atef
Publikováno v:
Scientia Pharmaceutica, Vol 91, Iss 3, p 38 (2023)
The aim of the study is to evaluate the effectiveness of the pediatric sofosbuvir weight-based dosing strategy in providing an equitable drug exposure compared to the marketed dose. The physiologically based pharmacokinetic (PBPK) modeling and simula
Externí odkaz:
https://doaj.org/article/0222117e208a4031bdb2e1edcebf0c4a
Publikováno v:
Sustainable Chemistry and Pharmacy. 33:101093
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 223:115165
Baloxavir marboxil (BXM) is a novel orally administrated prodrug for the treatment of acute uncomplicated influenza. In the present study, a bioanalytical LC-MS/MS method was developed and validated for the quantification of baloxavir acid (BXA), the
Publikováno v:
Microchemical Journal
Graphical abstract
Modern pharmaceutical analysis is paying a lot of attention to the stability of novel drug formulations as well as establishment of suitable stability-indicating approaches. In the current work, a comprehensive stability-indic
Modern pharmaceutical analysis is paying a lot of attention to the stability of novel drug formulations as well as establishment of suitable stability-indicating approaches. In the current work, a comprehensive stability-indic
Autor:
Amira S. Gouda, Hoda M. Marzouk, Mamdouh R. Rezk, Ahmed M. Salem, Mosaad I. Morsi, Eman G. Nouman, Youmna M. Abdallah, Ahmed Y. Hassan, Ahmed M. Abdel-Megied
Publikováno v:
Journal of Chromatography B. 1206:123363
A fully validated, simple, rapid and reproducible liquid chromatography-tandem mass spectrometry method was developed to determine NHC (N-hydroxycytidine), the active metabolite of Molnupiravir (MOL) in human plasma; one of the limited treatment opti
Autor:
Mosaad I. Morsy, Mamdouh R. Rezk, Ahmed M. Abdel-Megied, Mourd A. Zainelabdeen, Mohamed M. Darwish, Ahmed Y. Hassan, Amira S. Gouda, Youmna M. Abdallah, Hoda M. Marzouk, Eman G. Nouman
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis
Graphical abstract
A novel, fast and sensitive LC–MS/MS method was developed and validated for the bioanalysis of the antiviral agent favipiravir (FAV); a promising candidate for treatment of SARS-CoV-2 (COVID-19) in human plasma using pyrazin
A novel, fast and sensitive LC–MS/MS method was developed and validated for the bioanalysis of the antiviral agent favipiravir (FAV); a promising candidate for treatment of SARS-CoV-2 (COVID-19) in human plasma using pyrazin
Publikováno v:
Luminescence. 33:1094-1100
A simple, highly sensitive and selective spectrofluorimetric method has been developed and fully validated for the determination of daclatasvir (DAC) and ledipasvir (LED) in tablets and human plasma. The method is based on measurement of the native f
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 143
A highly sensitive and rapid LC-MS/MS method was developed, fully optimized and validated for the simultaneous determination of Ledipasvir (LED) and Sofosbuvir (SOF) in the presence of its major metabolite GS-331007 in human plasma using Daclatasvir
Publikováno v:
Biomedical Chromatography. 32:e4186
A simple and highly sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) bioanalytical method was developed and fully validated for the first time for the simultaneous determination of newly discovered antiviral drugs, namely sofosbuvi