Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Amira Bekdash"'
Autor:
Hana A. Itani, Miran A. Jaffa, Joseph Elias, Mohammad Sabra, Patrick Zakka, Jad Ballout, Amira Bekdash, Rand Ibrahim, Moustafa Al Hariri, Mirna Ghemrawi, Bernard Abi-Saleh, Maurice Khoury, Samir Alam, Rami Mahfouz, Ayad A. Jaffa, Sami T. Azar, Marwan M. Refaat
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Atrial fibrillation (AF) and cardiometabolic syndrome (CMS) have been linked to inflammation and fibrosis. However, it is still unknown which inflammatory cytokines contribute to the pathogenesis of AF. Furthermore, cardiometabolic syndrome (CMS) ris
Externí odkaz:
https://doaj.org/article/71e0044102ba460995f171cd80b17266
Autor:
Amira Bekdash, Manal Darwish, Zahra Timsah, Elias Kassab, Hadi Ghanem, Vicky Najjar, Marwan Ghosn, Selim Nasser, Hiba El-Hajj, Ali Bazerbachi, Shihui Liu, Stephen H. Leppla, Arthur E. Frankel, Ralph J. Abi-Habib
Publikováno v:
Translational Oncology, Vol 8, Iss 5, Pp 347-357 (2015)
In this study, we attempt to target both the urokinase plasminogen activator and the mitogen-activated protein kinase pathway in acute myeloid leukemia (AML) cell lines and primary AML blasts using PrAgU2/LF, a urokinase-activated anthrax lethal toxi
Externí odkaz:
https://doaj.org/article/e3a546f6ff5d4a54b4c56054715b8842
Autor:
Mirvat El-Sibai, Mirna Swayden, Amira Bekdash, Oula El-Atat, Isabelle Fakhoury, Ralph J. Abi-Habib, Jamila Borjac-Natour
Publikováno v:
Human Cell. 34:152-164
Deregulating cellular energetics by reprogramming metabolic pathways, including arginine metabolism, is critical for cancer cell onset and survival. Drugs that target the specific metabolic requirements of cancer cells have emerged as promising targe
Autor:
Nada J Habeichi, Hana A. Itani, Amira Bekdash, Cynthia Tannous, Fouad A. Zouein, Emna Abidi, Abdo Jurjus, Rima Farhat, George W. Booz, Rana Ghali, Abdullah Kaplan, Ziad Mallat
Publikováno v:
Clinical Science. 134:1191-1218
Myocardial infarction (MI) is the leading cause of mortality worldwide. Interleukin (IL)-33 (IL-33) is a cytokine present in most cardiac cells and is secreted on necrosis where it acts as a functional ligand for the ST2 receptor. Although IL-33/ST2
Autor:
Safaa Hammoud, Ibrahim AlZaim, Amira Bekdash, Nahed Mougharbil, Hana A Itani, Ahmed F El-Yazbi
Publikováno v:
Circulation. 144
Background: Early metabolic impairment is associated with significant cardiorenal risk. Specifically, subtle serum insulin and lipids changes in prediabetes trigger cardioautonomic and renovascular deterioration. Interestingly, data from our laborato
Publikováno v:
The FASEB Journal. 35
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257211 (2021)
PLoS ONE, Vol 16, Iss 9, p e0257211 (2021)
Traumatic brain injury (TBI) remains a major cause of morbidity and disability worldwide and a healthcare burden. TBI is an important risk factor for neurodegenerative diseases hallmarked by exacerbated neuroinflammation. Neuroinflammation in the cer
Publikováno v:
Journal of Biomedical Nanotechnology. 13:500-512
Autor:
Hiba El-Hajj, Elias Kassab, Zahra Timsah, Arthur E. Frankel, Selim M. Nasser, Hadi Ghanem, Amira Bekdash, Stephen H. Leppla, Shihui Liu, Vicky Najjar, Ralph J. Abi-Habib, Manal Darwish, Ali Bazerbachi, Marwan Ghosn
Publikováno v:
Translational Oncology, Vol 8, Iss 5, Pp 347-357 (2015)
In this study, we attempt to target both the urokinase plasminogen activator and the mitogen-activated protein kinase pathway in acute myeloid leukemia (AML) cell lines and primary AML blasts using PrAgU2/LF, a urokinase-activated anthrax lethal toxi
Publikováno v:
Asian Pacific Journal of Cancer Prevention. 16:761-767
Background: In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. Analysis of mechanism of cell d