Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Amira Abood"'
Autor:
Conor J. R. Scott, Nicholas G. S. McGregor, Daniel R. Leadbeater, Nicola C. Oates, Janina Hoßbach, Amira Abood, Alexander Setchfield, Adam Dowle, Herman S. Overkleeft, Gideon J. Davies, Neil C. Bruce
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 7 (2024)
ABSTRACT Parascedosporium putredinis NO1 is a plant biomass-degrading ascomycete with a propensity to target the most recalcitrant components of lignocellulose. Here we applied proteomics and activity-based protein profiling (ABPP) to investigate the
Externí odkaz:
https://doaj.org/article/5af28a9d52c443db935cb81de8b8bc98
Autor:
Mai H. ElNaggar, Abdullah A. Elgazar, Ghada Gamal, Shimaa M. Hamed, Zainab M. Elsayed, Mohamed K. El-Ashrey, Amira Abood, Mahmoud A. El Hassab, Ahmed M. Soliman, Ramadan A. El-Domany, Farid A. Badria, Claudiu T. Supuran, Wagdy M. Eldehna
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
SARS-CoV-2 pandemic in the end of 2019 led to profound consequences on global health and economy. Till producing successful vaccination strategies, the healthcare sectors suffered from the lack of effective therapeutic agents that could control the s
Externí odkaz:
https://doaj.org/article/7c870975f5504f1bb20870f051e5910f
Publikováno v:
Saudi Pharmaceutical Journal, Vol 26, Iss 3, Pp 349-357 (2018)
Although, fluconazole is widely used in clinical treatment as an antifungal drug, it recorded potential problems as resistance and intracellular accumulation. Female albino mice were injected with single ip dose of Candida albicans (1.5 × 106 CFU).
Externí odkaz:
https://doaj.org/article/e7ae286dcede4d78a2b1b6fc750b01a4
Publikováno v:
RSC Advances. 13:8049-8089
This review article provides an intensive state-of-the-art over the period 2000–2022 centred around the discovery, classifications, biosynthetic pathways and therapeutic potentialities of 351 structurally diverse fungal containing-isocoumarins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e726e468c8e36cc5fb798f9c54d645ca
https://doi.org/10.1039/d2ra08245d
https://doi.org/10.1039/d2ra08245d
Microorganisms still remain as main hotspots in the global drug discovery avenue. In particular, fungi are highly prolific producers of a vast of structurally divers specialised secondary metabolites, which have displayed a myriad of biomedical poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::686da255f905b0d08d2db5afaf55acee
https://doi.org/10.26434/chemrxiv-2023-slfmk
https://doi.org/10.26434/chemrxiv-2023-slfmk
Autor:
Marwa A. Sh. Shehab, Mardia T. El Sayed, Shaymaa A. Ismail, Hala M. El Kafrawy, Nermien M. Sabry, Rabab A. Ismail, Mohamed El-Naggar, Amira Abood
Publikováno v:
Current Bioactive Compounds. 16:514-520
Background: Amongst the quinolone core structures, 8-hydroxyquinoline (8-HQ or quinolinol) stands out as the greatest frequently used therapeutic moietiy. This includes the most critical molecules in medicinal chemistry. Quinolinol remains a broad-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8005bfff7538d28acfddc6e2c31526d5
https://doi.org/10.2174/1573407215666190131112730
https://doi.org/10.2174/1573407215666190131112730
Publikováno v:
Drug Development Research. 81:374-388
The main goal of this study was to prepare and evaluate nanosponges containing ciprofloxacin (CIP) or its binary mixture with N-acetyl carnosine (NAC). Nanosponges were prepared by ultrasound-assisted synthesis technique using hydroxypropyl βeta-cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78585610e8c06b443e289f8e8d174d61
https://doi.org/10.1002/ddr.21632
https://doi.org/10.1002/ddr.21632
Autor:
Nicola C. Oates, Yi Li, Susannah Bird, Alexandra M. Schirmacher, Sarah Liu, Daniel R. Leadbeater, Vitaliy I. Tymokhin, Neil C. Bruce, Anna M. Alessi, Amira Abood, Simon J. McQueen-Mason, John Ralph, Joseph P. Bennett, Adam Dowle
Publikováno v:
Proc Natl Acad Sci U S A
Lignocellulose, the structural component of plant cells, is a major agricultural byproduct and the most abundant terrestrial source of biopolymers on Earth. The complex and insoluble nature of lignocellulose limits its conversion into value-added com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6210631c32ae2d2e6f4f630606cbdab2
https://doi.org/10.1073/pnas.2008888118
https://doi.org/10.1073/pnas.2008888118
Autor:
Amr E. El-Hakim, Asmaa M.M. Salman, Amira Abood, Azza M. Abdel-Aty, Azza M. Abdel-Fattah, Amal M. Hashem
Publikováno v:
International Journal of Biological Macromolecules. 116:801-810
A thermostable metallo-collagenase enzyme (150 kDa), recently identified in a newly isolated actinomycestes strain (Nocardiopsis dassonvillei NRC2aza), has been purified from natural source, characterized to have application in wound healing. A simpl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f014921f3ae0aa21bacfec0370adcb
https://doi.org/10.1016/j.ijbiomac.2018.05.030
https://doi.org/10.1016/j.ijbiomac.2018.05.030
Autor:
Keith J. Flanagan, Mathias O. Senge, Alina Meindl, Hoda I. El Diwani, Amira Abood, Heba T. Abdel-Mohsen
Publikováno v:
Archiv der Pharmazie. 353:1900271
In the present study, a novel series of polyfunctionalized imidazopyrimidines 6a-u and 9a-d were efficiently constructed by a domino reaction between 2-imino-6-substituted-2,3-dihydropyrimidin-4(1H)-ones 4a-d or 8a-c and 2-bromoacetophenones 5a-i und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a9832b07bbe2f94e1eb4875474ea56
https://doi.org/10.1002/ardp.201900271
https://doi.org/10.1002/ardp.201900271