Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Amir Taldaev"'
Autor:
Roman P. Terekhov, Anastasiya D. Savina, Denis I. Pankov, Maria D. Korochkina, Amir Taldaev, Liubov M. Yakubovich, Sergey P. Zavadskiy, Anastasiya K. Zhevlakova, Irina A. Selivanova
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Dihydroquercetin (DHQ) is a representative of flavonoids that is available on the market as a food supplement and registered as an active pharmaceutical ingredient. The structure of this compound is characterized by the presence of two chiral centers
Externí odkaz:
https://doaj.org/article/1018de7c81ce4c82bc36889ad00246ed
Autor:
Amir Taldaev, Roman Terekhov, Ilya Nikitin, Elizaveta Melnik, Vera Kuzina, Mikhail Klochko, Igor Reshetov, Artem Shiryaev, Victor Loschenov, Galina Ramenskaya
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Methylene blue has a long history of clinical application. Thanks to phenothiazine chromophore, it has potential in photodynamic anticancer therapy. In spite of the growing body of literature that has evaluated the action of this dye on d
Externí odkaz:
https://doaj.org/article/9fd0195c32324f6897b29fca8a2cd68e
Autor:
Maria O. Ershova, Amir Taldaev, Petr V. Konarev, Georgy S. Peters, Anastasia A. Valueva, Irina A. Ivanova, Sergey V. Kraevsky, Andrey F. Kozlov, Vadim S. Ziborov, Yuri D. Ivanov, Alexander I. Archakov, Tatyana O. Pleshakova
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1776 (2023)
Currently, there is great interest in the development of highly sensitive bioanalytical systems for diagnosing diseases at an early stage, when pathological biomarkers are present in biological fluids at low concentrations and there are no clinical m
Externí odkaz:
https://doaj.org/article/db7e3b81c4924f898331b5ad0410d92b
Autor:
Amir Taldaev, Denis I. Pankov, Roman P. Terekhov, Anastasia K. Zhevlakova, Irina A. Selivanova
Publikováno v:
Pharmaceutics, Vol 15, Iss 11, p 2607 (2023)
Bioavailability is an important biopharmaceutical characteristic of active pharmaceutical ingredients (APIs) that is often correlated with their solubility in water. One of the methods of increasing solubility is freeze drying (lyophilization). The a
Externí odkaz:
https://doaj.org/article/adffed92a5e84aba948e3d93221ebf1d
Autor:
Amir Taldaev, Roman P. Terekhov, Irina A. Selivanova, Denis I. Pankov, Maria N. Anurova, Irina Yu. Markovina, Zhaoqing Cong, Siqi Ma, Zhengqi Dong, Feifei Yang, Yonghong Liao
Publikováno v:
Scientia Pharmaceutica, Vol 90, Iss 4, p 67 (2022)
Taxifolin is known as an active pharmaceutical ingredient (API) and food supplement due to its high antioxidant activity, multiple pharmacological effects, and good safety profile. Previously, taxifolin spheres (TS) were obtained from industrially pr
Externí odkaz:
https://doaj.org/article/2b705f37769f4822b4d1c50e47d79454
Autor:
Amir Taldaev, Roman P. Terekhov, Elizaveta V. Melnik, Maria V. Belova, Sergey V. Kozin, Andrey A. Nedorubov, Tatyana Ya. Pomerantseva, Galina V. Ramenskaya
Publikováno v:
Toxins, Vol 14, Iss 7, p 490 (2022)
Jervine, protoveratrine A (proA), and protoveratrine B (proB) are Veratrum alkaloids that are presented in some remedies obtained from Veratrum lobelianum, such as Veratrum aqua. This paper reports on a single-center pilot cardiotoxic mechanism study
Externí odkaz:
https://doaj.org/article/dca528c13e894d4286778631c1080c01
Publikováno v:
Molecules, Vol 27, Iss 4, p 1386 (2022)
The three-dimensional structure of monomers and homodimers of CYP102A1/WT (wild-type) proteins and their A83F and A83I mutant forms was predicted using the AlphaFold2 (AF2) and AlphaFold Multimer (AFMultimer) programs, which were compared with the ra
Externí odkaz:
https://doaj.org/article/88eeace09fea4791a3dc953839aeaa1b
Autor:
Amir Taldaev, Vladimir Rudnev, Liudmila Kulikova, Kirill Nikolsky, Alexander Efimov, Kristina Malsagova, Anna Kaysheva
Publikováno v:
Proteomes, Vol 10, Iss 1, p 8 (2022)
Biological activity regulation by protein post-translational modification (PTM) is critical for cell function, development, differentiation, and survival. Dysregulation of PTM proteins is present in various pathological conditions, including rheumato
Externí odkaz:
https://doaj.org/article/434143afdd6a4d49bc332873e025eef8
Publikováno v:
Pharmaceuticals, Vol 15, Iss 1, p 30 (2021)
Rheumatoid arthritis (RA) is a chronic disease characterized by bone joint damage and incapacitation. The mechanism underlying RA pathogenesis is autoimmunity in the connective tissue. Cytokines play an important role in the human immune system for s
Externí odkaz:
https://doaj.org/article/30e64dd1c02341e5890ca61160d6d568
Autor:
Dmitry Tikhonov, Liudmila Kulikova, Vladimir Rudnev, Arthur T. Kopylov, Amir Taldaev, Alexander Stepanov, Kristina Malsagova, Alexander Izotov, Dmitry Enikeev, Natalia Potoldykova, Anna Kaysheva
Publikováno v:
Diagnostics, Vol 11, Iss 10, p 1836 (2021)
Post-translational modification (PTM) leads to conformational changes in protein structure, modulates the biological function of proteins, and, consequently, changes the signature of metabolic transformations and the immune response in the body. Comm
Externí odkaz:
https://doaj.org/article/8fd05e25aafc47ea8ec53d1e936f7867