Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Amir Rattner"'
Publikováno v:
eLife, Vol 12 (2023)
Bacterial meningitis is a major cause of morbidity and mortality, especially among infants and the elderly. Here, we study mice to assess the response of each of the major meningeal cell types to early postnatal E. coli infection using single nucleus
Externí odkaz:
https://doaj.org/article/da5b93be0e0a4dcd89458987359323ba
Publikováno v:
eLife, Vol 10 (2021)
The iris controls the level of retinal illumination by controlling pupil diameter. It is a site of diverse ophthalmologic diseases and it is a potential source of cells for ocular auto-transplantation. The present study provides foundational data on
Externí odkaz:
https://doaj.org/article/8fea2d0934074d4982e113780fd77067
Autor:
Amir Rattner, Chantelle E Terrillion, Claudia Jou, Tina Kleven, Shun Felix Hu, John Williams, Zhipeng Hou, Manisha Aggarwal, Susumu Mori, Gloria Shin, Loyal A Goff, Menno P Witter, Mikhail Pletnikov, André A Fenton, Jeremy Nathans
Publikováno v:
eLife, Vol 9 (2020)
In the hippocampus, a widely accepted model posits that the dentate gyrus improves learning and memory by enhancing discrimination between inputs. To test this model, we studied conditional knockout mice in which the vast majority of dentate granule
Externí odkaz:
https://doaj.org/article/efecf045371b47e199262306c5499373
Publikováno v:
eLife, Vol 8 (2019)
The brain, spinal cord, and retina are supplied by capillaries that do not permit free diffusion of molecules between serum and parenchyma, a property that defines the blood-brain and blood-retina barriers. Exceptions to this pattern are found in cir
Externí odkaz:
https://doaj.org/article/f6f0a4d1dfb04f2aaf593a9fdef03632
Autor:
Xi Peng, Francesco Emiliani, Philip M Smallwood, Amir Rattner, Hong Lei, Mark F Sabbagh, Jeremy Nathans
Publikováno v:
eLife, Vol 7 (2018)
Defining protein-protein interactions (PPIs) is central to the biological sciences. Here, we present a novel platform - Affinity Capture of Polyribosomes followed by RNA sequencing (ACAPseq) - for identifying PPIs. ACAPseq harnesses the power of mass
Externí odkaz:
https://doaj.org/article/eeee0facf6ee466ba8f06831b70840ff
Autor:
Mark F Sabbagh, Jacob S Heng, Chongyuan Luo, Rosa G Castanon, Joseph R Nery, Amir Rattner, Loyal A Goff, Joseph R Ecker, Jeremy Nathans
Publikováno v:
eLife, Vol 7 (2018)
Vascular endothelial cell (EC) function depends on appropriate organ-specific molecular and cellular specializations. To explore genomic mechanisms that control this specialization, we have analyzed and compared the transcriptome, accessible chromati
Externí odkaz:
https://doaj.org/article/561fe078565b4184bf69573280bb6c71
Publikováno v:
eLife, Vol 2 (2013)
The use of the least squares method to calculate the best-fitting line through a two-dimensional scatter plot typically requires the user to assume that one of the variables depends on the other. However, in many cases the relationship between the tw
Externí odkaz:
https://doaj.org/article/b3cb598889434a92ac52a04556dfcc7c
The iris controls the level of retinal illumination by controlling pupil diameter. It is a site of diverse ophthalmological diseases and it is a potential source of cells for ocular auto-transplantation. The present study provides foundational data o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04a46f4dced277d71ad5a449a249aa50
https://doi.org/10.1101/2021.09.10.459739
https://doi.org/10.1101/2021.09.10.459739
Autor:
Loyal A. Goff, Jacob S Heng, Jeremy Nathans, Briana L. Winer, Amir Rattner, Hilary J. Vernon, Bryan W. Jones, Genevieve Stein-O’Brien
Publikováno v:
Proceedings of the National Academy of Sciences. 116:9103-9114
The mammalian CNS is capable of tolerating chronic hypoxia, but cell type-specific responses to this stress have not been systematically characterized. In the Norrin KO ( Ndp KO ) mouse, a model of familial exudative vitreoretinopathy (FEVR), develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c954abc026711afe9e3990f60a3598e9
https://doi.org/10.1073/pnas.1821122116
https://doi.org/10.1073/pnas.1821122116