Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Amir R Afshari"'
Autor:
Seyed Hadi Mousavi, Mohammad Jalili-Nik, Mohammad Soukhtanloo, Arash Soltani, Farzaneh Abbasinezhad-Moud, Hamid Mollazadeh, Farzaneh Shakeri, Bahram Bibak, Amirhossein Sahebkar, Amir R. Afshari
Publikováno v:
Avicenna Journal of Phytomedicine, Vol 14, Iss 3, Pp 349-364 (2024)
Objective: The present work examined the anti-metastatic effects of auraptene and their underlying mechanisms of action in U87 Glioblastoma multiforme (GBM) cells.Materials and Methods: To test the hypothesis, cell culture, Matrigel invasion assay, s
Externí odkaz:
https://doaj.org/article/e46d9982bce34feb9b4d4c1b7943f4f6
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 8, p 408 (2023)
Standard cancer chemotherapeutics often produce significant adverse effects and eventually lose their effectiveness due to the emergence of resistance mechanisms. As a result, patients with malignant tumors experience a poor quality of life and a sho
Externí odkaz:
https://doaj.org/article/6d6ec8dc9d244499a1b595a23b2d740c
Autor:
Mehdi Sanati, Maryam Moradi Binabaj, Seyed Sajad Ahmadi, Samaneh Aminyavari, Hossein Javid, Hamid Mollazadeh, Bahram Bibak, Elmira Mohtashami, Tannaz Jamialahmadi, Amir R. Afshari, Amirhossein Sahebkar
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 155, Iss , Pp 113740- (2022)
Despite conventional treatment options including chemoradiation, patients with the most aggressive primary brain tumor, glioblastoma multiforme (GBM), experience an average survival time of less than 15 months. Regarding the malignant nature of GBM,
Externí odkaz:
https://doaj.org/article/a5c429610f3e41c9ac087c895f06cf49
Ferula gummosa gum exerts cytotoxic effects against human malignant glioblastoma multiforme in vitro
Autor:
Amir R. Afshari, Seyed Hadi Mousavi, Golrokh Mousavi, Sanam Daneshpour Moghadam, Abolfazl Maghrouni, Hossein Javid, Zahra Tayarani-Najaran, Bahram Bibak, Hamid Mollazadeh, Azar Hosseini
Publikováno v:
Research in Pharmaceutical Sciences, Vol 17, Iss 5, Pp 585-593 (2022)
Background and purpose: Ferula gummosa (F. gummosa), a potent medicinal herb, has been shown to possess anticancer activities in vitro. The present examination evaluated the cytotoxic and apoptogenic impacts of F. gummosa gum on the U87 glioblastoma
Externí odkaz:
https://doaj.org/article/7ac325457a3b4af7ae1829852e89a726
Autor:
Mehdi Sanati, Amir R. Afshari, Javad Amini, Hamid Mollazadeh, Tannaz Jamialahmadi, Amirhossein Sahebkar
Publikováno v:
Journal of Functional Foods, Vol 96, Iss , Pp 105192- (2022)
Solid tumors rely on pathological angiogenesis to meet their metabolic needs and facilitate their spread. Glioblastoma multiforme (GBM), an aggressive and deadliest brain malignancy, is represented by multi-mechanistic and exuberant angiogenic proper
Externí odkaz:
https://doaj.org/article/bab60306906d41898c5bd50a25063126
Autor:
Amir R. Afshari, Sahar Fanoudi, Arezoo Rajabian, Hamid Reza Sadeghnia, Hamid Mollazadeh, Azar Hosseini
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 23, Iss 9, Pp 1113-1123 (2020)
Glutamate, as an essential neurotransmitter, has been thought to have different roles in the central nervous system (CNS), including nerve regeneration, synaptogenesis, and neurogenesis. Excessive glutamate causes an up-regulation of the multiple sig
Externí odkaz:
https://doaj.org/article/67716177ed7a4baebadc2d91b09c7b65
Harmaline exerts potentially anti-cancer effects on U-87 human malignant glioblastoma cells in vitro
Autor:
Mohammad Mahdi Vahedi, Ali Shahini, Mehran Mottahedi, Setareh Garousi, Seyed Ali Shariat Razavi, Ghazaleh pouyamanesh, Amir R. Afshari, Gordon A. Ferns, Afsane Bahrami
Publikováno v:
Molecular Biology Reports. 50:4357-4366
Autor:
Seyed Hadi Mousavi, Roghayeh Rashidi, Amir R. Afshari, Shirin Ghasemian, Mohammad Soukhtanloo, Mohammad Sadegh Amiri
Publikováno v:
Letters in Drug Design & Discovery. 20:279-290
Objective: Thymus transcaspicus (Lamiaceae) is an Iranian species of Thymus, and Ungernia trisphaera Bunge belongs to the family Amaryllidaceae. Cytotoxic properties of total ethanolic extract of T. transcaspicus and U. trisphaera were investigated a
Autor:
Amir R. Afshari, Mostafa Karimi Roshan, Mohammad Soukhtanloo, Ahmad Ghorbani, Farzad Rahmani, Mohammad Jalili-nik, Mohammad Mahdi Vahedi, Azar Hoseini, Hamid R. Sadeghnia, Hamid Mollazadeh, Seyed Hadi Mousavi
Publikováno v:
Avicenna Journal of Phytomedicine, Vol 9, Iss 4, Pp 334-346 (2019)
Objective: Glioblastoma multiforme (GBM) is the deadliest type of primary brain tumors, and the survival of patients is estimated to be only about one year. This study, for the first time, investigated the cytotoxic effects of auraptene on U87 GBM ce
Externí odkaz:
https://doaj.org/article/b9ded1982e534fb5b52e4dd388e1f858
Autor:
Farzaneh Abbasinezhad-Moud, Farshad Mirzavi, Hassan Rakhshandeh, Reza Mohebbati, Fatemeh Forouzanfar, Mohammad Jalili-Nik, Nadia Azadi, Mehdi Sanati, Amir R. Afshari, Mohammad Soukhtanloo
Publikováno v:
Alternatives to Laboratory Animals. 51:30-38
The pathological accumulation of quinolinic acid (QA) is often associated with neuritis and neuronal cell death in several neurodegenerative diseases, through the overproduction of free radicals. Urolithin B and auraptene have been reported to exert