Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Amir F. Ayyobi"'
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 7, Pp 1279-1286 (2003)
Hepatic lipase (HL) plays a central role in LDL and HDL remodeling. High HL activity is associated with small, dense LDL particles and with reduced HDL2 cholesterol levels. HL activity is determined by an HL gene promoter polymorphism, by gender (low
Externí odkaz:
https://doaj.org/article/dd3ec4df31474ce393ad09c2945ba497
Autor:
Jonas Peterson, Amir F. Ayyobi, Yuanhong Ma, Howard Henderson, Manuel Reina, Samir S. Deeb, Silvia Santamarina-Fojo, Michael R. Hayden, John D. Brunzell
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 3, Pp 398-406 (2002)
Missense mutations in exon 5 of the LPL gene are the most common reported cause of LPL deficiency. Exon 5 is also the region with the strongest homology to pancreatic and hepatic lipase, and is conserved in LPL from different species. Mutant LPL prot
Externí odkaz:
https://doaj.org/article/49bbb49ebbb347dbbfe6cd26c5657e44
Publikováno v:
International Congress Series. 1303:85-94
Premature coronary artery disease classic risk factors primarily include increased low-density lipoprotein cholesterol (LDL-C) and decreased high-density lipoprotein cholesterol (HDL-C), as more recently shown elevated apolipoprotein B or reduced apo
Publikováno v:
Atherosclerosis. 181:363-369
Cardiac rehabilitation programs (CR) are standard treatment for patients with coronary artery disease (CAD), yet a large variation in risk factor and lipoprotein changes exists. We investigated the role of three common genetic polymorphisms (CETP Taq
Autor:
G.B. John Mancini, Jiri Frohlich, Sammy Chan, John S. Hill, Amir F. Ayyobi, Sandra H. McGladdery
Publikováno v:
Atherosclerosis. 177:361-366
We have reassessed the clinical and biochemical status of a large Canadian kindred with LCAT deficiency 25 years after the initial investigations. There have been no vascular events or death in this family over the 25 years. Both the homozygous (N =
Autor:
Christelle Foucher, Stephanie Rattier, David M. Flavell, John J.P. Kastelein, Jean-Claude Ansquer, Philippa J. Talmud, Steve E. Humphries, Simon N. Pimstone, George Steiner, Amir F. Ayyobi, Jiri Frohlich
Publikováno v:
Pharmacogenetics, 14(12), 823-829. Lippincott Williams and Wilkins
Objective The association between polymorphisms in candidate genes related to lipoprotein metabolism and the reduction in plasma triglyceride (TG) in response to fenofibrate treatment was evaluated in subjects with type 2 diabetes treated with micron
Autor:
John D. Brunzell, Amir F Ayyobi
Publikováno v:
The American Journal of Cardiology. 92:27-33
Metabolic abnormalities associated with the metabolic syndrome are also present in patients with type 2 diabetes mellitus and in those with familial combined hyperlipidemia (FCHL). These abnormalities include central obesity, insulin resistance with
Autor:
Melissa A. Austin, Arno G. Motulsky, Amir F Ayyobi, Marguerite J. McNeely, John D. Brunzell, Sandra H. McGladdery
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 23:1289-1294
Objective— Familial combined hyperlipidemia (FCHL) is associated with variable lipid and lipoprotein phenotypes arbitrarily defined as type IIa, IIb, and IV based on plasma total cholesterol and triglyceride levels. This study sought to characteriz
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 22:667-673
Hepatic lipase (HL) and cholesteryl ester transfer protein (CETP) have been independently associated with low density lipoprotein (LDL) and high density lipoprotein (HDL) size in different cohorts. These studies have been conducted mainly in men and
Autor:
Yuanhong Ma, Silvia Santamarina-Fojo, Jonas Peterson, Michael R. Hayden, Howard E. Henderson, John D. Brunzell, Manuel Reina, Samir S. Deeb, Amir F. Ayyobi
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 3, Pp 398-406 (2002)
Missense mutations in exon 5 of the LPL gene are the most common reported cause of LPL deficiency. Exon 5 is also the region with the strongest homology to pancreatic and hepatic lipase, and is conserved in LPL from different species. Mutant LPL prot