Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Amir Ali Abbasi"'
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Over the course of the COVID-19 pandemic, several SARS-CoV-2 variants have emerged that may exhibit different etiological effects such as enhanced transmissibility and infectivity. However, genetic variations that reduce virulence and deteri
Externí odkaz:
https://doaj.org/article/cbbb80dbd22b4143861a3b5ea6e51099
Autor:
Hizran Khatoon, Rabail Zehra Raza, Shoaib Saleem, Fatima Batool, Saba Arshad, Muhammad Abrar, Shahid Ali, Irfan Hussain, Neil H. Shubin, Amir Ali Abbasi
Publikováno v:
BMC Molecular and Cell Biology, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Background Human accelerated regions (HARs) are short conserved genomic sequences that have acquired significantly more nucleotide substitutions than expected in the human lineage after divergence from chimpanzees. The fast evolution of HARs
Externí odkaz:
https://doaj.org/article/d505f9f7b2bd4954a5240f23461ba72f
Autor:
Muhammad Saqib Nawaz, Razia Asghar, Nashaiman Pervaiz, Shahid Ali, Irfan Hussain, Peiqi Xing, Yiming Bao, Amir Ali Abbasi
Publikováno v:
BMC Evolutionary Biology, Vol 20, Iss 1, Pp 1-15 (2020)
Abstract Background Parkinson’s disease (PD) is the second most common neurodegenerative disorder. PD associated human UCHL1 (Ubiquitin C-terminal hydrolase L1) gene belongs to the family of deubiquitinases and is known to be highly expressed in ne
Externí odkaz:
https://doaj.org/article/f6b08083005a4beb9e55638785c528db
Autor:
Nashaiman Pervaiz, Nazia Shakeel, Ayesha Qasim, Rabail Zehra, Saneela Anwar, Neenish Rana, Yongbiao Xue, Zhang Zhang, Yiming Bao, Amir Ali Abbasi
Publikováno v:
BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background The hypothesis that vertebrates have experienced two ancient, whole genome duplications (WGDs) is of central interest to evolutionary biology and has been implicated in evolution of developmental complexity. Three-way and Four-way
Externí odkaz:
https://doaj.org/article/27059cd805af419db832ec93fc746898
Publikováno v:
BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Frizzled family members belong to G-protein coupled receptors and encode proteins accountable for cell signal transduction, cell proliferation and cell death. Members of Frizzled receptor family are considered to have critical rol
Externí odkaz:
https://doaj.org/article/02c94dbd1fbd4785bc77abbeed166d3c
Publikováno v:
Evolutionary Bioinformatics, Vol 2009, Iss 5, Pp 5-13 (2009)
Background: In vertebrates the “SONIC HEDGEHOG” signalling pathway has been implicated in cell-fate determination, proliferation and the patterning of many different cell types and organs. As the GLI family members (GLI1, GLI2 and GLI3) are key m
Externí odkaz:
https://doaj.org/article/61d79f1a395f412186209d427b2d7615
Autor:
Amir Ali Abbasi, Zissis Paparidis, Sajid Malik, Debbie K Goode, Heather Callaway, Greg Elgar, Karl-Heinz Grzeschik
Publikováno v:
PLoS ONE, Vol 2, Iss 4, p e366 (2007)
The zinc-finger transcription factor GLI3 is a key regulator of development, acting as a primary transducer of Sonic hedgehog (SHH) signaling in a combinatorial context dependent fashion controlling multiple patterning steps in different tissues/orga
Externí odkaz:
https://doaj.org/article/d88ba954cf0949eba4fb7bd8a081542d
Publikováno v:
eLS. :1-8
Publikováno v:
BMC Ecology and Evolution, Vol 21, Iss 1, Pp 1-9 (2021)
BMC Ecology and Evolution
BMC Ecology and Evolution
Background There has been a rapid increase in the brain size relative to body size during mammalian evolutionary history. In particular, the enlarged and globular brain is the most distinctive anatomical feature of modern humans that set us apart fro
Publikováno v:
Development Genes and Evolution. 231:21-32
The zinc finger-containing transcription factor Gli3 is a key mediator of Hedgehog (Hh) signaling pathway. In vertebrates, Gli3 has widespread expression pattern during early embryonic development. Along the anteroposterior axes of the central nervou