Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Amir Al Khami"'
Autor:
Paramita Chakraborty, Silvia G. Vaena, Krishnamurthy Thyagarajan, Shilpak Chatterjee, Amir Al-Khami, Shanmugam Panneer Selvam, Hung Nguyen, Inhong Kang, Megan W. Wyatt, Uday Baliga, Zachariah Hedley, Rose N. Ngang, Beichu Guo, Gyda C. Beeson, Shahid Husain, Chrystal M. Paulos, Craig C. Beeson, Michael J. Zilliox, Elizabeth G. Hill, Meenal Mehrotra, Xue-Zhong Yu, Besim Ogretmen, Shikhar Mehrotra
Publikováno v:
Cell Reports, Vol 28, Iss 7, Pp 1879-1893.e7 (2019)
Summary: Sphingosine 1-phosphate (S1P), a bioactive lysophospholipid generated by sphingosine kinase 1 (SphK1), regulates lymphocyte egress into circulation via S1P receptor 1 (S1PR1) signaling, and it controls the differentiation of regulatory T cel
Externí odkaz:
https://doaj.org/article/7f8c2775b7694880b2a02c17a884d38d
Autor:
Youssef Errami, Hassan Ashktorab, Augusto C. Ochoa, Abdelmetalab Tarhuni, Ali H. El-Bahrawy, Amir Al Khami, Hamid Boulares, Paulo C. Rodriguez, Amarjit S. Naura, Hassan Brim
Publikováno v:
The FASEB Journal. 29
Important causes of colon cancer in humans are chronic colon inflammation and the accumulation of mutations. PARP-1 is involved in genomic stability and inflammatory processes, which are anti- and ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9ecb1bff3fff6d4de7f1b64724843c1
https://doi.org/10.1096/fasebj.29.1_supplement.629.11
https://doi.org/10.1096/fasebj.29.1_supplement.629.11
Autor:
Moselhy S Mansy, Paulo C. Rodriguez, Claudia Hernandez, Hamid Boulares, Augusto C. Ochoa, Amir Al Khami, Mohamed A. Ghonim, Amarjit S. Naura
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1861870581d948c9e19b6355b3560069
https://doi.org/10.1096/fasebj.27.1_supplement.1107.1
https://doi.org/10.1096/fasebj.27.1_supplement.1107.1
Autor:
David J. Cole, Amir Al Khami, C. Marcela Diaz-Montero, Alberto J. Montero, Mohamed L. Salem, Sabry A. El Naggar, Randa E. El Naggar
Publikováno v:
Cancer immunology, immunotherapy : CII. 57(4)
During the antigen-dependant activation process several subsets CD8+ T cells appear with different phenotypic and functional characteristics. Recent studies indicate that the state of T cell differentiation radically affects their ability to effectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ea66438469502e8f562c79336bf525
https://pubmed.ncbi.nlm.nih.gov/17726606
https://pubmed.ncbi.nlm.nih.gov/17726606
Publikováno v:
The Journal of Immunology. 194:141.30-141.30
Myeloid-derived suppressor cell (MDSC) suppression of anti-tumor T cell responses is a significant barrier in cancer immunotherapy. Although pathways controlling MDSC regulatory activity have been characterized, therapies to globally and specifically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6454a0d959587496630193aad632efa4
https://doi.org/10.4049/jimmunol.194.supp.141.30
https://doi.org/10.4049/jimmunol.194.supp.141.30
Autor:
Amir Al-Khami, Mohamed Ghonim, Kusma Pyakurel, Salome Ibba, Jimena Trillo-Tinoco, Fokhrul Hossain, Luis Del Valle, Paulo Rodriguez, Hamid Boulares, Augusto Ochoa
Publikováno v:
The Journal of Immunology. 194:53.21-53.21
Background: There has been a growing appreciation for the role of energy metabolic pathways in the differentiation and function of immune cells. Unpublished findings from our laboratory suggest that inhibiting fatty acid oxidation (FAO) modulates the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf6733dfb10ac4aece5fc28a6f1693e9
https://doi.org/10.4049/jimmunol.194.supp.53.21
https://doi.org/10.4049/jimmunol.194.supp.53.21
Autor:
Mohamed Ghonim, Kusma Pyakurel, Salomi Ibba, Amir Al-Khami, Jeffery Wang, Paulo Rodriguez, Hamada Rady, Ali El-Bahrawy, Matthew Lammi, Alistair Ramsay, Moselhy Mansy, Augusto Ochoa, Amarjit Naura, Hamid Boulares
Publikováno v:
The Journal of Immunology. 194:53.5-53.5
An important portion of asthmatics do not respond to current therapies. Thus, the need for new therapeutic drugs becomes urgent. We have demonstrated a critical role for PARP in experimental asthma. In the current study, we test the efficacy of Olapa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46a3d5ca36eda0ebb34960b0aff78e60
https://doi.org/10.4049/jimmunol.194.supp.53.5
https://doi.org/10.4049/jimmunol.194.supp.53.5
Autor:
Fokhrul Hossain, Amir Al-Khami, Dorota Wyczechowska, Claudia Hernandez, Liqin Zheng, Krzystoff Reiss, Luis Del Valle, Jimena Trillo-Tinoco, Paulo Rodriguez, Augusto Ochoa
Publikováno v:
The Journal of Immunology. 194:141.8-141.8
Myeloid-derived suppressor cells (MDSC) promote tumor growth by inhibiting T cell immunity through various mechanisms including the depletion of arginine and the production of nitric oxide and peroxinitrites. Blocking of any single mechanism has only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fb86684ca7aa96edaa9cd35287989ac
https://doi.org/10.4049/jimmunol.194.supp.141.8
https://doi.org/10.4049/jimmunol.194.supp.141.8
Autor:
Krishnamurthy Thyagarajan, Amir Al-Khami, Suriyan Ponnusamy, Beichu Guo, Besim Ogretmen, Shikhar Mehrotra
Publikováno v:
The Journal of Immunology. 192:73.13-73.13
Sphingosine kinase 1(Sphk1) is a key enzyme in sphingolipid metabolism that is involved in the production of sphingosine-1-phosphate (S1P). S1P controls many cellular processes such as cell proliferation, migration and cytokine production. We sought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d529a379d5fcb73c700ecbe4ce0b1c31
https://doi.org/10.4049/jimmunol.192.supp.73.13
https://doi.org/10.4049/jimmunol.192.supp.73.13
Autor:
Pravin Kesarwani, Amir Al-Khami, Navtej Kaur, Quan Fang, Osama Naga, Gyda Beeson, Christina Johnson, Elizabeth Mayer, Craig Beeson, Michael Nishimura, Shikhar Mehrotra
Publikováno v:
The Journal of Immunology. 190:65.18-65.18
Ex vivo-expanded CD8+ T cells used for adoptive immunotherapy generally acquire an effector memory-like phenotype (TEM cells) and exhibit impaired in vivo persistence and anti-tumor efficacy, compared to T cells with central memory-like phenotype (TC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e8c377176aea9ac92da0d8047f25d52
https://doi.org/10.4049/jimmunol.190.supp.65.18
https://doi.org/10.4049/jimmunol.190.supp.65.18