Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Amir, Vahabikashi"'
Autor:
Suganya Sivagurunathan, Amir Vahabikashi, Haiqian Yang, Jun Zhang, Kelly Vazquez, Dhivyaa Rajasundaram, Yuliya Politanska, Hiam Abdala-Valencia, Jacob Notbohm, Ming Guo, Stephen A. Adam, Robert D. Goldman
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Vimentin is a Type III intermediate filament (VIF) cytoskeletal protein that regulates the mechanical and migratory behavior of cells. Its expression is considered to be a marker for the epithelial to mesenchymal transition (EMT) that takes place in
Externí odkaz:
https://doaj.org/article/77d566af8a374e9e9a874adf3df64d39
Publikováno v:
APL Bioengineering, Vol 6, Iss 1, Pp 011503-011503-11 (2022)
Nuclear lamins are type V intermediate filament proteins that polymerize into complex filamentous meshworks at the nuclear periphery and in less structured forms throughout the nucleoplasm. Lamins interact with a wide range of nuclear proteins and ar
Externí odkaz:
https://doaj.org/article/11845f71dba34e3d8071d5a8b75a421e
Autor:
Amir Vahabikashi, Suganya Sivagurunathan, Fiona Ann Sadsad Nicdao, Yu Long Han, Chan Young Park, Mark Kittisopikul, Xianrong Wong, Joseph R. Tran, Gregg G. Gundersen, Karen L. Reddy, G. W. Gant Luxton, Ming Guo, Jeffrey J. Fredberg, Yixian Zheng, Stephen A. Adam, Robert D. Goldman
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The ability of a cell to regulate its mechanical properties is central to its function. Emerging evidence suggests that interactions between the cell nucleus and cytoskeleton influence cell mechanics through poorly understood mechanisms. Here we cond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30db962e59a0d9fa90a517242523184b
https://doi.org/10.1073/pnas.2121816119
https://doi.org/10.1073/pnas.2121816119
Publikováno v:
Bioinformatics
Motivation Microscopy images of cytoskeletal, nucleoskeletal and other structures contain complex junctions of overlapping filaments with arbitrary geometry. Yet, state-of-the-art algorithms generally perform single orientation analysis to segment th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b65f116636c0b260f640beaacf96ae
https://doi.org/10.1093/bioinformatics/btaa627
https://doi.org/10.1093/bioinformatics/btaa627
Autor:
Robert D. Goldman, Anne E. Goldman, Rong Qiu, Hawa Racine Thiam, Denisa D. Wagner, Amir Vahabikashi, Clare M. Waterman, Mark Kittisopikul, Siu Ling Wong
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Neutrophils are white blood cells specialized as the first line of host defense in the immune system. One way they protect organisms is through NETosis, in which they expel their DNA to form a web-like trap that ensnares pathogens and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b608e012fb7e26a9d6b5f5f49fe0e3e
http://europepmc.org/articles/PMC7132277
http://europepmc.org/articles/PMC7132277
Autor:
Ariel Gelman, Biqin Dong, Haiyan Gong, Elliott D. K. Cha, Cheng Sun, Lihua Gong, Kristin Perkumas, Hao Zhang, W. Daniel Stamer, Ernst R. Tamm, Amir Vahabikashi, Mark Johnson, Margit Schimmel
Publikováno v:
Proc Natl Acad Sci U S A
The cause of the elevated outflow resistance and consequent ocular hypertension characteristic of glaucoma is unknown. To investigate possible causes for this flow resistance, we used atomic force microscopy (AFM) with 10-µm spherical tips to probe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc562458fc79bade92a1722f29e3bc50
https://doi.org/10.1073/pnas.1911837116
https://doi.org/10.1073/pnas.1911837116
Autor:
Stephen A. Adam, Karen L. Reddy, Suganya Sivagurunathan, Chan Young Park, Robert D. Goldman, Yixian Zheng, Tran, Wong X, Jeffrey J. Fredberg, Gregg G. Gundersen, Amir Vahabikashi, Nicdao Fas, Ming Guo, Yu Long Han, Luxton Gg
The ability of a cell to regulate its mechanical properties is central to its function. Emerging evidence suggests that interactions between the cell nucleus and cytoskeleton influence cell mechanics through poorly understood mechanisms. Here we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59d2872e5ecc95c3d1aa2059959c0ddd
https://doi.org/10.1101/2021.05.12.443683
https://doi.org/10.1101/2021.05.12.443683
Autor:
Anne E. Goldman, Clare M. Waterman, Denisa D. Wagner, Robert D. Goldman, Amir Vahabikashi, Hawa Racine Thiam, Mark Kittisopikul, Rong Qiu, Siu Ling Wong
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
We used quantitative, high-resolution live-cell imaging of neutrophil-like human cells (dHL60) and mouse and human blood-derived polymorphonuclear neutrophils (PMNs) stimulated with ionomycin, lipopolysaccharide (LPS), or Candida albicans to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d8f83cee796c053041b55e635f0439
https://pubmed.ncbi.nlm.nih.gov/32943582
https://pubmed.ncbi.nlm.nih.gov/32943582
Autor:
Colleen M. McDowell, Krishnakumar Kizhatil, Michael H. Elliott, Darryl R. Overby, Joseph van Batenburg-Sherwood, J. Cameron Millar, Markus H. Kuehn, Gulab Zode, Ted S. Acott, Michael G. Anderson, Sanjoy K. Bhattacharya, Jacques A. Bertrand, Terete Borras, Diane E. Bovenkamp, Lin Cheng, John Danias, Michael Lucio De Ieso, Yiqin Du, Jennifer A. Faralli, Rudolf Fuchshofer, Preethi S. Ganapathy, Haiyan Gong, Samuel Herberg, Humberto Hernandez, Peter Humphries, Simon W. M. John, Paul L. Kaufman, Kate E. Keller, Mary J. Kelley, Ruth A. Kelly, David Krizaj, Ajay Kumar, Brian C. Leonard, Raquel L. Lieberman, Paloma Liton, Yutao Liu, Katy C. Liu, Navita N. Lopez, Weiming Mao, Timur Mavlyutov, Fiona McDonnell, Gillian J. McLellan, Philip Mzyk, Andrews Nartey, Louis R. Pasquale, Gaurang C. Patel, Padmanabhan P. Pattabiraman, Donna M. Peters, Vijaykrishna Raghunathan, Ponugoti Vasantha Rao, Naga Rayana, Urmimala Raychaudhuri, Ester Reina-Torres, Ruiyi Ren, Douglas Rhee, Uttio Roy Chowdhury, John R. Samples, E. Griffen Samples, Najam Sharif, Joel S. Schuman, Val C. Sheffield, Cooper H. Stevenson, Avinash Soundararajan, Preeti Subramanian, Chenna Kesavulu Sugali, Yang Sun, Carol B. Toris, Karen Y. Torrejon, Amir Vahabikashi, Janice A. Vranka, Ting Wang, Colin E. Willoughby, Chen Xin, Hongmin Yun, Hao F. Zhang, Michael P. Fautsch, Ernst R. Tamm, Abbot F. Clark, C. Ross Ethier, W. Daniel Stamer
Publikováno v:
Investigative ophthalmology & visual science, vol 63, iss 2
Due to their similarities in anatomy, physiology, and pharmacology to humans, mice are a valuable model system to study the generation and mechanisms modulating conventional outflow resistance and thus intraocular pressure. In addition, mouse models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2366dca55a396f9cef10de74cc76d5
https://doi.org/10.1167/iovs.63.2.12
https://doi.org/10.1167/iovs.63.2.12
Microscopy images of cytoskeletal, nucleoskeletal, and other filamentous structures contain complex junctions where multiple filaments with distinct orientations overlap, yet state-of-the-art software generally uses single orientation analysis to seg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e709a370523a1d17561e9071f7d5288
https://doi.org/10.1101/757005
https://doi.org/10.1101/757005