Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Amir, Onn"'
Autor:
Vladimir Lazar, Eric Raymond, Shai Magidi, Catherine Bresson, Fanny Wunder, Ioana Berindan-Neagoe, Annemilaï Tijeras-Rabaland, Jacques Raynaud, Amir Onn, Michel Ducreux, Gerald Batist, Ulrik Lassen, Fin Cilius Nielsen, Richard L. Schilsky, Eitan Rubin, Razelle Kurzrock
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Dysregulated pathways in cancer may be hub addicted. Identifying these dysregulated networks for targeting might lead to novel therapeutic options. Objective: Considering the hypothesis that central hubs are associated with increased leth
Externí odkaz:
https://doaj.org/article/da12cb09d31d4454bd2113b0c027167a
Autor:
Ofir Deri, David Ovadia, Ella Huszti, Michael Peled, Milton Saute, Tammy Hod, Amir Onn, Lior Seluk, Nadav Furie, Inbal Shafran, Ronen Mass, Sumit Chatterji, Liran Levy
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 18 (2024)
Background: Interstitial lung diseases (ILD) unresponsive to medical therapy often require lung transplantation (LTx), which prolongs quality of life and survival. Ideal timing for referral for LTx remains challenging, with late referral associated w
Externí odkaz:
https://doaj.org/article/4ddb303d164943ceb62bcce779d54e71
Autor:
Benjamin Solomon, Ana Callejo, Jair Bar, Guy Berchem, Lyudmila Bazhenova, Pierre Saintigny, Fanny Wunder, Jacques Raynaud, Nicolas Girard, J. Jack Lee, Raed Sulaiman, Bruce Prouse, Catherine Bresson, Hila Ventura, Shai Magidi, Eitan Rubin, Brandon Young, Amir Onn, Brian Leyland‐Jones, Richard L. Schilsky, Vladimir Lazar, Enriqueta Felip, Razelle Kurzrock
Publikováno v:
Cancer Medicine, Vol 11, Iss 14, Pp 2790-2800 (2022)
Abstract Background The Worldwide Innovative Network (WIN) Consortium has developed the Simplified Interventional Mapping System (SIMS) to better define the cancer molecular milieu based on genomics/transcriptomics from tumor and analogous normal tis
Externí odkaz:
https://doaj.org/article/9a1795592c8e42cab3df58cfe6f8ac80
Autor:
Akram Saad, Jeffrey Goldstein, Sarit Appel, Sameh Daher, Damien Urban, Amir Onn, Hadas Gantz‐Sorotsky, Anastasiya Lobachov, Teodor Gottfried, Benjamin Spieler, Jair Bar
Publikováno v:
Thoracic Cancer, Vol 13, Iss 12, Pp 1763-1771 (2022)
Abstract Objective Compare outcomes in patients with stage III non–small cell lung cancer (NSCLC) treated with chemoradiation and adjuvant durvalumab to historical controls treated with chemoradiation alone. Methods The records of patients with sta
Externí odkaz:
https://doaj.org/article/97943ea374354c0d97eaffe2590b20ae
Autor:
Vladimir Lazar, Baolin Zhang, Shai Magidi, Christophe Le Tourneau, Eric Raymond, Michel Ducreux, Catherine Bresson, Jacques Raynaud, Fanny Wunder, Amir Onn, Enriqueta Felip, Josep Tabernero, Gerald Batist, Razelle Kurzrock, Eitan Rubin, Richard L. Schilsky
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Background: The current model of clinical drug development in oncology displays major limitations due to a high attrition rate in patient enrollment in early phase trials and a high failure rate of drugs in phase III studies. Objective: Integrating t
Externí odkaz:
https://doaj.org/article/59159a57b2d143e3be0bcdbaf9afc021
Autor:
Vladimir Lazar, Jacques Raynaud, Shai Magidi, Catherine Bresson, Jean-François Martini, Susan Galbraith, Fanny Wunder, Amir Onn, Gerald Batist, Nicolas Girard, Ulrik Lassen, C. S. Pramesh, Amal Al-Omari, Sadakatsu Ikeda, Guy Berchem, Jean-Yves Blay, Benjamin Solomon, Enriqueta Felip, Josep Tabernero, Eitan Rubin, Thierry Philip, Angel Porgador, Ioana Berindan-Neagoe, Richard L. Schilsky, Razelle Kurzrock
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Background: SARS-CoV-2 (COVID-19) elicits a T-cell antigen-mediated immune response of variable efficacy. To understand this variability, we explored transcriptomic expression of angiotensin-converting enzyme 2 ( ACE2 , the SARS-CoV-2 receptor) and o
Externí odkaz:
https://doaj.org/article/cacbf20affbf406896e87fc22d539ae7
Autor:
Michael Peled, David Ovadya, Jennifer Cohn, Lior Seluk, Teet Pullerits, Michael J. Segel, Amir Onn
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background Methacholine challenge tests (MCTs) are used to diagnose airway hyperresponsiveness (AHR) in patients with suspected asthma where previous diagnostic testing has been inconclusive. The test is time consuming and usually requires r
Externí odkaz:
https://doaj.org/article/56ae3f352b0b47068239c97b35429156
Autor:
Vladimir Lazar, Shai Magidi, Nicolas Girard, Alexia Savignoni, Jean-François Martini, Giorgio Massimini, Catherine Bresson, Raanan Berger, Amir Onn, Jacques Raynaud, Fanny Wunder, Ioana Berindan-Neagoe, Marina Sekacheva, Irene Braña, Josep Tabernero, Enriqueta Felip, Angel Porgador, Claudia Kleinman, Gerald Batist, Benjamin Solomon, Apostolia Maria Tsimberidou, Jean-Charles Soria, Eitan Rubin, Razelle Kurzrock, Richard L. Schilsky
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-12 (2021)
Abstract The expanding targeted therapy landscape requires combinatorial biomarkers for patient stratification and treatment selection. This requires simultaneous exploration of multiple genes of relevant networks to account for the complexity of mec
Externí odkaz:
https://doaj.org/article/03d1a19c53bf406b8f14275e04c89c95
Autor:
Or Sehayek, Waleed Kian, Amir Onn, Ronen Stoff, Hadas Gantz Sorotsky, Melanie Zemel, Jair Bar, Yulia Dudnik, Hovav Nechushtan, Yakir Rottenberg, Lior Soussan-Gutman, Addie Dvir, Laila C. Roisman, Nir Peled
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
PurposeMolecular profiling is crucial in naïve non-small cell lung cancer (NSCLC). While tissue-based analysis is challenged by turnaround time and scarcity of tissue, there is increasing demand for liquid biopsy. We aimed to analyze the use of upfr
Externí odkaz:
https://doaj.org/article/85362ec588224779aae89838b8d19a1d
Autor:
Ari Raphael, Amir Onn, Liran Holtzman, Julia Dudnik, Damien Urban, Waleed Kian, Aharon Y. Cohen, Mor Moskovitz, Alona Zer, Jair Bar, Natalie Maimon Rabinovich, Shirly Grynberg, Cecilie Oedegaard, Abed Agbarya, Nir Peled, Tzippy Shochat, Elizabeth Dudnik
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundThe use of CGP in guiding treatment decisions in aNSCLC with acquired resistance to ALK TKIs is questionable.MethodsWe prospectively assessed the impact of CGP on the decision-making process in ALK-rearranged aNSCLC patients following progr
Externí odkaz:
https://doaj.org/article/f85c5c5f27684af1b3b0753d584f245f