Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Amir, Behdad"'
Autor:
Lorenzo Gerratana, Andrew A. Davis, Marko Velimirovic, Katherine Clifton, Whitney L. Hensing, Ami N. Shah, Charles S. Dai, Carolina Reduzzi, Paolo D’Amico, Firas Wehbe, Arielle Medford, Seth A. Wander, William J. Gradishar, Amir Behdad, Fabio Puglisi, Cynthia X. Ma, Aditya Bardia, Massimo Cristofanilli
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-12 (2023)
Abstract Background although being central for the biology and druggability of hormone-receptor positive, HER2 negative metastatic breast cancer (MBC), ESR1 and PIK3CA mutations are simplistically dichotomized as mutated or wild type in current clini
Externí odkaz:
https://doaj.org/article/e709c732d873422f9a1a421cdc570023
Autor:
Andrew A. Davis, Lorenzo Gerratana, Katherine Clifton, Arielle J. Medford, Marko Velimirovic, Whitney L. Hensing, Leslie Bucheit, Ami N. Shah, Paolo D'Amico, Carolina Reduzzi, Qiang Zhang, Charles S. Dai, Elyssa N. Denault, Nusayba A. Bagegni, Mateusz Opyrchal, Foluso O. Ademuyiwa, Ron Bose, William J. Gradishar, Amir Behdad, Cynthia X. Ma, Aditya Bardia, Massimo Cristofanilli
Publikováno v:
EBioMedicine, Vol 86, Iss , Pp 104316- (2022)
Summary: Background: Limited data exist to characterise molecular differences in circulating tumour DNA (ctDNA) for patients with invasive lobular carcinoma (ILC). We analysed metastatic breast cancer patients with ctDNA testing to assess genomic dif
Externí odkaz:
https://doaj.org/article/07b125b3c92b42acba72a92a3f8e5d48
Publikováno v:
Case Reports in Hematology, Vol 2022 (2022)
Mantle cell lymphoma (MCL) is an aggressive, difficult to treat subtype of lymphoma, resulting in relapses and poor outcomes. Novel agents such as Bruton tyrosine kinase (BTK) inhibitors have been studied in the treatment of relapsed/refractory (R/R)
Externí odkaz:
https://doaj.org/article/6ee13fbbe6674fbd952bc7f410ec2ccc
Autor:
Andrew A. Davis, Qiang Zhang, Lorenzo Gerratana, Ami N. Shah, Youbin Zhan, Wenan Qiang, Brian S. Finkelman, Lisa Flaum, Amir Behdad, William J. Gradishar, Leonidas C. Platanias, Massimo Cristofanilli
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-8 (2019)
Abstract Purpose Liquid biopsies, including circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs), can be used to understand disease prognosis, tumor heterogeneity, and dynamic response to treatment in metastatic breast cancer (MBC). We ex
Externí odkaz:
https://doaj.org/article/40cd0501b4a249ad80a0c2b4426a8492
Autor:
Luigi Formisano, Yao Lu, Alberto Servetto, Ariella B. Hanker, Valerie M. Jansen, Joshua A. Bauer, Dhivya R. Sudhan, Angel L. Guerrero-Zotano, Sarah Croessmann, Yan Guo, Paula Gonzalez Ericsson, Kyung-min Lee, Mellissa J. Nixon, Luis J. Schwarz, Melinda E. Sanders, Teresa C. Dugger, Marcelo Rocha Cruz, Amir Behdad, Massimo Cristofanilli, Aditya Bardia, Joyce O’Shaughnessy, Rebecca J. Nagy, Richard B. Lanman, Nadia Solovieff, Wei He, Michelle Miller, Fei Su, Yu Shyr, Ingrid A. Mayer, Justin M. Balko, Carlos L. Arteaga
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Era+ breast cancer patients often develop resistance to endocrine therapy. Here, the authors show that FGFR1 amplification is a resistance mechanism to CDK4/6 inhibitor and endocrine therapy and that combined treatment with FGFR, CDK4/6, and anti-est
Externí odkaz:
https://doaj.org/article/c9a8bb9c2aac44dba476758c76c4a8d4
Autor:
Hakan Demirci, Rajesh C. Rao, Victor M. Elner, F. Yesim Demirci, Lev Axenov, Bryan Betz, Amir Behdad, Noah Brown
Publikováno v:
Ophthalmology Retina. 7:189-195
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0989b5a86313a843e29415c3f4f18888
https://doi.org/10.1016/j.oret.2022.08.005
https://doi.org/10.1016/j.oret.2022.08.005
Publikováno v:
EClinicalMedicine, Vol 26, Iss , Pp 100475- (2020)
Background: The outbreak of coronavirus disease 2019 (COVID-19) in December 2019 overlaps with the flu season. Methods: We compared clinical and laboratory results from 719 influenza and 973 COVID-19 patients from January to April 2020. We compiled l
Externí odkaz:
https://doaj.org/article/4df831bb916049f4af1140faf8a9f20a
Autor:
Andrew A. Davis, Saya Jacob, Lorenzo Gerratana, Ami N. Shah, Firas Wehbe, Neelima Katam, Qiang Zhang, Lisa Flaum, Kalliopi P. Siziopikou, Leonidas C. Platanias, William J. Gradishar, Amir Behdad, Massimo Cristofanilli
Publikováno v:
EBioMedicine, Vol 58, Iss , Pp 102914- (2020)
Background: We describe the genomic landscape of circulating tumour DNA (ctDNA) across pathological subtypes of metastatic breast cancer. Methods: 255 clinically annotated patients with ctDNA testing by Guardant360 were stratified into HR+, HER2+, an
Externí odkaz:
https://doaj.org/article/7c72c58ca777465db403e0194fc0c7e0
Autor:
Sarah M. Choi, Aleodor A. Andea, Min Wang, Amir Behdad, Lina Shao, Yanming Zhang, Xinyan Lu, David Dittmann, Juan Castro, Yi-Hua Chen, Juehua Gao
Publikováno v:
Diagnostic Pathology, Vol 13, Iss 1, Pp 1-13 (2018)
Abstract Background Transformation of follicular lymphoma most typically occurs as diffuse large B-cell lymphoma, however other forms of transformation such as classic Hodgkin lymphoma and lymphoblastic transformation can occur. Secondary malignant h
Externí odkaz:
https://doaj.org/article/1a19af6c826943608eab7a34b5cecfca
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Our understanding of the genetics and treatment options for primary effusion lymphoma (PEL) is lacking. Here the authors performed in vitro CRISPR/Cas9 knock-out screens to identify 210 PEL-specific oncogenic genes and report strategies for therapeut
Externí odkaz:
https://doaj.org/article/4753b6af0a0c4636a623f9ba180cea46