Zobrazeno 1 - 10
of 540
pro vyhledávání: '"Aminoglycoside modifying enzymes"'
Publikováno v:
Medical Journal of Babylon, Vol 21, Iss 3, Pp 590-598 (2024)
Background:Pseudomonas aeruginosa is one of the most prevalent Gram-negative microbes associated with serious and fatal nosocomial infections. It is routine to use aminoglycosides as a treatment for P. aeruginosa infections. Objectives:The disseminat
Externí odkaz:
https://doaj.org/article/62c5d7fe55e342978caf273a839eee83
Autor:
Sara Al-janaby, Mayada Shehan
Publikováno v:
مجلة جامعة الانبار للعلوم الصرفة, Vol 17, Iss 2, Pp 5-11 (2023)
Pseudomonas aeruginosa is an opportunistic pathogen that causes a variety of infections throughout the world, including bacteremia in immunocompromised patients, wound and soft tissue infections, hospital-acquired pneumonia, respiratory infections, a
Externí odkaz:
https://doaj.org/article/44f113b565664967b3bc3938ced3b7af
Publikováno v:
Iranian Journal of Microbiology, Vol 16, Iss 2 (2024)
Background and Objectives: Escherichia coli is a significant causative agent of bloodstream infections (BSIs). Aminoglycoside antibiotics play a crucial role in treating severe infections such as sepsis and pneumonia. However, resistance to these ant
Externí odkaz:
https://doaj.org/article/3b6c9473214d4477bc2e2c13b3ab6b99
Autor:
Jan Sklenicka, Tung Tran, Maria S. Ramirez, Haley M. Donow, Angel J. Magaña, Travis LaVoi, Yasir Mamun, Verónica Jimenez, Prem Chapagain, Radleigh Santos, Clemencia Pinilla, Marc A. Giulianotti, Marcelo E. Tolmasky
Publikováno v:
Antibiotics, Vol 13, Iss 7, p 672 (2024)
Resistance to amikacin and other major aminoglycosides is commonly due to enzymatic acetylation by the aminoglycoside 6′-N-acetyltransferase type I enzyme, of which type Ib [AAC(6′)-Ib] is the most widespread among Gram-negative pathogens. Findin
Externí odkaz:
https://doaj.org/article/c197c7880abf460db84e42d2d2218354
Autor:
Giancarlo Atassi, Rachel Medernach, Marc Scheetz, Sophia Nozick, Nathaniel J. Rhodes, Megan Murphy-Belcaster, Katherine R. Murphy, Arghavan Alisoltani, Egon A. Ozer, Alan R. Hauser
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Pseudomonas aeruginosa frequently becomes resistant to aminoglycosides by the acquisition of aminoglycoside modifying enzyme (AME) genes and the occurrence of mutations in the mexZ, fusA1, parRS, and armZ genes. We examined resistance to ami
Externí odkaz:
https://doaj.org/article/106b4f8e66be4fb681ebc4a84ed2e1a1
Autor:
Saeed Khoshnood, Sousan Akrami, Morteza Saki, Moloudsadat Motahar, Sara Masihzadeh, Sara Daneshfar, Hossein Meghdadi, Effat Abbasi Montazeri, Marjan Abdi, Zahra Farshadzadeh
Publikováno v:
Health Science Reports, Vol 6, Iss 5, Pp n/a-n/a (2023)
Abstract Background and Aims Resistance to antibiotics and the capability to develop biofilm as two main virulent determinants of Klebsiella pneumoniae have important role in infection persistence. The aim of the study was to evaluate the association
Externí odkaz:
https://doaj.org/article/268483f702e6422d9da710687b9871a6
Publikováno v:
Journal of Pure and Applied Microbiology, Vol 15, Iss 4, Pp 2420-2430 (2021)
Antimicrobial resistance gene profile characterization and dissemination offer useful detail on the possible challenge in treating bacteria. The development of aminoglycoside modifying enzymes (AMEs) is considered as the primary mechanism of resistan
Externí odkaz:
https://doaj.org/article/329de0f0eb704bfd99acb8c3cb276d82
Publikováno v:
Microorganisms, Vol 11, Iss 9, p 2351 (2023)
The spread of nosocomial infections caused by antibiotic-resistant Enterococcus faecalis is one of the major threats to global health at present. While aminoglycosides are often used to combat these infections, their effectiveness is reduced by vario
Externí odkaz:
https://doaj.org/article/2dbbe718ca334f6baa1b35fc2ec1be18
Autor:
Nuoyan Wang, Xuemin Chen, Jing Luo, Fei Deng, Fuguo Shi, Qin Wu, Yasi Huang, Qin Ouyang, Rongxin Qin, Hong Zhou
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Bacterial resistance is becoming increasingly serious, the present study aimed to investigate the mechanism of antibacterial sensitization effect of DHA27 combined with tobramycin in tobramycin-resistant Pseudomonas aeruginosa (PA). We found that DHA
Externí odkaz:
https://doaj.org/article/de75250ed0b14bfb877ac50c676a5390
Publikováno v:
Iranian Journal of Microbiology, Vol 14, Iss 3 (2022)
Background and Objectives: Aminoglycosides have been widely used for treating severe staphylococcal infections. Production aminoglycoside modifying enzymes (AMEs) is the main mechanism of resistance to this antibiotic. The aim of this study was to de
Externí odkaz:
https://doaj.org/article/7e1d2b6bc27445fc8ce300eeddec323b