Metabolic engineering combined with site-directed saturated mutations of α-keto acid decarboxylase for efficient production of 6-aminocaproic acid and 1,6-hexamethylenediamine.

Autor: Wang T; Innovation Center for Textile Science and Technology, College of Biological Science and Medical Engineering, Donghua University, Shanghai, People's Republic of China., Ye P; Innovation Center for Textile Science and Technology, College of Biological Science and Medical Engineering, Donghua University, Shanghai, People's Republic of China., Xu X; Innovation Center for Textile Science and Technology, College of Biological Science and Medical Engineering, Donghua University, Shanghai, People's Republic of China., Lu M; Innovation Center for Textile Science and Technology, College of Biological Science and Medical Engineering, Donghua University, Shanghai, People's Republic of China., Zhang X; Innovation Center for Textile Science and Technology, College of Biological Science and Medical Engineering, Donghua University, Shanghai, People's Republic of China., Li N; Innovation Center for Textile Science and Technology, College of Biological Science and Medical Engineering, Donghua University, Shanghai, People's Republic of China.

Publikováno v: Biotechnology and bioengineering [Biotechnol Bioeng] 2024 Oct; Vol. 121 (10), pp. 3329-3337. Date of Electronic Publication: 2024 Jul 02.

Antifibrinolytic and Adjunct Hemostatic Agents: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference.

Autor: Moynihan KM; Department of Cardiology, Boston Children's Hospital, Boston, MA.; Department of Pediatrics, Harvard Medical School, Boston, MA.; Faculty of Medicine and Health, Children's Hospital at Westmead Clinical School, University of Sydney, Sydney, NSW, Australia.; Department of Pediatric Cardiac Intensive Care, Stollery Children's Hospital, Edmonton, AB, Canada.; Department of Pediatrics, University of Alberta Hospital, Edmonton, AB, Canada.; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA.; Department of Pathology, Nationwide Children's Hospital, Columbus, OH.; Division of Clinical Pharmacology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT.; Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT.; Division of Pediatric Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI.; Division of Critical Care Medicine, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH.; Ohio State University College of Medicine, Columbus, OH.; Grant Morrow III MD Medical Library, Nationwide Children's Hospital Columbus, Columbus, OH.; Divisions of Hematology/Oncology and Critical Care, Department of Pediatrics, University of Minnesota, Minnesota, MN., Ryerson LM; Department of Pediatric Cardiac Intensive Care, Stollery Children's Hospital, Edmonton, AB, Canada.; Department of Pediatrics, University of Alberta Hospital, Edmonton, AB, Canada., Le J; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA., Nicol K; Department of Pathology, Nationwide Children's Hospital, Columbus, OH., Watt K; Division of Clinical Pharmacology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT.; Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT., Gadepalli SK; Division of Pediatric Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI., Alexander PMA; Department of Cardiology, Boston Children's Hospital, Boston, MA.; Department of Pediatrics, Harvard Medical School, Boston, MA., Muszynski JA; Division of Critical Care Medicine, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH.; Ohio State University College of Medicine, Columbus, OH., Gehred A; Grant Morrow III MD Medical Library, Nationwide Children's Hospital Columbus, Columbus, OH., Lyman E; Grant Morrow III MD Medical Library, Nationwide Children's Hospital Columbus, Columbus, OH., Steiner ME; Divisions of Hematology/Oncology and Critical Care, Department of Pediatrics, University of Minnesota, Minnesota, MN.

Publikováno v: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies [Pediatr Crit Care Med] 2024 Jul 01; Vol. 25 (7 Suppl 1), pp. e44-e52. Date of Electronic Publication: 2024 Jul 03.

An interlaboratory capillary zone electrophoresis-UV study of various monoclonal antibodies, instruments, and ε-aminocaproic acid lots.

Autor: Wiesner R; Institute of Medicinal and Pharmaceutical Chemistry, Technische Universität Braunschweig, Braunschweig, Germany., Zagst H; Institute of Medicinal and Pharmaceutical Chemistry, Technische Universität Braunschweig, Braunschweig, Germany., Lan W; Bristol Myers Squibb, New Brunswick, New Jersey, USA., Bigelow S; Health Canada, Ottawa, Ontario, Canada., Holper P; AB SCIEX LLC, Redwood City, California, USA., Hübner G; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riß, Germany., Josefsson L; Kantisto BV, Baarn, The Netherlands., Lancaster C; Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Lo L; Bristol Myers Squibb, New Brunswick, New Jersey, USA., Lößner C; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riß, Germany., Lu H; Health Canada, Ottawa, Ontario, Canada., Neusüß C; Faculty Chemistry, Hochschule Aalen, Aalen, Germany., Rüttiger C; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riß, Germany., Schlecht J; Faculty Chemistry, Hochschule Aalen, Aalen, Germany., Schürrle P; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riß, Germany., Selsam A; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riß, Germany., van der Burg D; Institute of Medicinal and Pharmaceutical Chemistry, Technische Universität Braunschweig, Braunschweig, Germany.; Kantisto BV, Baarn, The Netherlands.; Department of Chemistry, School of Engineering Sciences in Chemistry, KTH Royal Institute of Technology, Stockholm, Sweden., Wang SC; Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Zhu Y; Bristol Myers Squibb, New Brunswick, New Jersey, USA., Wätzig H; Institute of Medicinal and Pharmaceutical Chemistry, Technische Universität Braunschweig, Braunschweig, Germany., Sänger-van de Griend C; Institute of Medicinal and Pharmaceutical Chemistry, Technische Universität Braunschweig, Braunschweig, Germany.; Kantisto BV, Baarn, The Netherlands.; Department of Medicinal Chemistry, Faculty of Pharmacy, Uppsala University, Uppsala, Sweden.

Publikováno v: Electrophoresis [Electrophoresis] 2023 Aug; Vol. 44 (15-16), pp. 1247-1257. Date of Electronic Publication: 2023 May 11.

The Optimal Dose, Efficacy and Safety of Tranexamic Acid and Epsilon-Aminocaproic Acid to Reduce Bleeding in TKA: A Systematic Review and Bayesian Network Meta-analysis.

Autor: Zheng C; Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China., Ma J; Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China., Xu J; Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China., Li M; Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China., Wu L; Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China., Wu Y; Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China., Liu Y; Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China., Shen B; Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China.

Publikováno v: Orthopaedic surgery [Orthop Surg] 2023 Apr; Vol. 15 (4), pp. 930-946. Date of Electronic Publication: 2023 Mar 06.

Bleeding Reversal With Antifibrinolytics or Cryoprecipitate Following Thrombolysis for Acute Ischemic Stroke: A Case Series.

Autor: Bailey AM; Author Affiliations: University of Kentucky HealthCare Pharmacy Services, Lexington, KY (Drs Platt Baum, Nestor, and Bailey); and Department of Emergency Medicine, University of Kentucky College of Medicine, Lexington, KY (D. Baum)., Baum R, Nestor M, Platt T

Publikováno v: Advanced emergency nursing journal [Adv Emerg Nurs J] 2024 Apr-Jun 01; Vol. 46 (2), pp. 101-107. Date of Electronic Publication: 2024 May 09.